Joining Dr. Stephanie is the incredible Annette Verpillot for a journey through light roast discussions, where they explore the broad strokes of posture's influence, followed by medium roast insights, delving deeper into the mechanics and intricacies. In the dark roast segment, they dive headfirst into the nerdy details, exploring everything from the vestibular system to semicircular canals.

Throughout the conversation, they cover it all – from head to feet, and even the surprising importance of jaw and tongue alignment. Plus, brace yourself for a fascinating discussion on dentistry and pediatric neurology. It's a holistic approach to wellness that will leave you feeling informed and inspired. And as a special treat, Annette has a gift in store for you at the end of the show – so be sure to stick around!

Episode Overview:
0:00 Intro/Teaser
4:01 Exploring the Impact of Posture on Muscle Development
10:45 Analyzing Gait and Foot Mechanics
37:35 The Role of Therapeutic Insoles in Posture Correction
44:33 Neuroanatomical Examination of the Eyes
47:54 Indirect Effects of Eye Movements on the Brain
54:32 Eye Movements and Dopamine Levels
59:55 Tongue Posture and Oral Development
1:01:53 Eye Muscles and Sympathetic Response
1:04:59 Jaw Imbalance and Head Position
1:10:29 Impact of Wisdom Teeth Removal
1:14:37 Mouth Breathing and Learning Disabilities
1:16:50 Hope in Correcting Tongue Posture
1:20:05 Use of Functional Activators for Children
1:23:20 Importance of Posture for Longevity
1:25:25 Discount Offer and Course Information

Resources mentioned:
Sleep Difficulties and Symptoms of Attention-deficit Hyperactivity Disorder in Children with Mouth Breathing - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645617/
Visit https://shop.posturepro.co and use the discount code BETTER15 to get a 15% discount on all products and courses.

Bio:

Annette Verpillot, the founder of Posturepro, is a Canadian entrepreneur, therapist, and internationally recognized Posture Specialist know for her expertise in restoring the brain-body connection. Her groundbreaking Posturepro Method, taught to professionals worldwide, incorporates advanced rehabilitation and injury prevention techniques. Annette's renowned postural evaluation system has a proven track record of eliminating chronic pain, enhancing strength, and improving sports performance. Through industry events and media appearances, Annette advocates for good posture, leaving a lasting impact on global health. Find out more at https://shop.posturepro.co

We are grateful to our sponsors:

BON CHARGE
I am doubling down on this year for my best skin ever. The Bon Charge Red Light Face Mask helps with glowing, younger, firmer-looking skin with minimal effort or time AND without really changing your usual day or night routine. Head over to https://boncharge.com/better and use the discount code BETTER at checkout to get 15% off your entire cart.

BODYBIO
Fish Oil Plus, alongside the balance oil, are the two oils that I use for myself and my family on a daily basis. We take it straight up with a tablespoon, but it also mixes really well into smoothies and you can also drizzle it over your salad. Head over to https://bodybio.com/better and use code BETTER at checkout to get 15% off your first order.

ONESKIN
It’s time for a radical shift in skin care. This year I am doubling down on skin health and OneSkin is one of the ways I am getting my 40-year-old skin to behave like 20-year-old skin. Visit https://www.oneskin.co/?utm_source=partner&utm_medium=podcast&utm_campaign=BETTER and use the code BETTER at checkout to save 15%.

Dr. Casey Means uncovers the ancestral roots of mitochondrial health and discusses the modern-day factors contributing to illness and fatigue. Both Dr. Means and Dr. Stephanie provide invaluable insights and actionable tips for optimizing health.

Covering topics such as nutrition, sleep, stress, and lifestyle factors, this conversation offers a wealth of knowledge for listeners at any stage of their health journey. Tune in to discover the secrets to unlocking your full health potential and embarking on a journey to self-optimization.

Episode Overview:
0:00 Intro/teaser
3:45 Unveiling Mitochondrial Health
11:58 Healthcare System and Root Cause Issues
20:35 Empowering Patients to Take Control
25:33 Modern Food, Health, and Technology
41:12 Building Meals: Components for Cellular Health
38:59 Optimizing Health Through Nutrition and Thermoneutrality
43:40 The Impact of Indoor Living on our Biology
45:03 Harnessing Cosmic Energy Through Mitochondrial Health
46:38 Incorporating Temperature Play into Daily Life
50:47 The Importance of Movement and Walking
55:33 The Influence of Artificial Light on Circadian Rhythms58:57 Utilizing Wearables to Track Movement
1:01:50 Embracing Sunlight and Overcoming Fear
1:14:02 Fearlessness as the Ultimate Good Energy
1:19:30 Connecting with the Eternal Source of Life

Resources mentioned:

Good Energy by Dr. Casey Means is a paradigm-shifting book that offers a radical new understanding of the roots of disease and highlights the importance of optimizing our metabolic health. - https://www.caseymeans.com/goodenergy

Trends and Disparities in Cardiometabolic Health Among U.S. Adults, 1999-2018 - https://www.sciencedirect.com/science/article/pii/S0735109722049944?via%3Dihub

Steps per Day and All-Cause Mortality in Middle-aged Adults in the Coronary Artery Risk Development in Young Adults Study - https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2783711

The Mini Pause newsletter - https://drstephanieestima.com/newsletter/

Bio:
Casey Means, MD is a Stanford-trained physician and co-founder of Levels, a health technology company with the mission of reversing the world’s metabolic health crisis. Her book on metabolic health, Good Energy, comes out in May 2024 with Penguin Random House. She received her BA with honors and MD from Stanford, was President of her Stanford class, and has served on Stanford faculty. She trained in Head & Neck Surgery before leaving traditional medicine to devote her life to tackling the root cause of why Americans are sick. She has been featured in The New York Times, The New Yorker, The Wall Street Journal, Forbes, Women’s Health, and more. Find out more at https://www.caseymeans.com/

We are grateful to our sponsors:

EQUIP PRIME PROTEIN

Equip Foods Prime Protein is a complete bovine protein with the nutritional equivalent of 4-ounces of grass-fed beef. The best part is, it tastes like dessert, not beef. I use it all the time in my baking efforts when I'm trying to sneak in more protein. Head over to https://equipfoods.com/better and use code BETTER at checkout to get 20% off of your order.

PRIMEADINE

Primeadine has been shown to support memory, cognition, heart health, balanced hormones, and improved hair growth and fullness. If you are interested in trying it out, go to https://OxfordHealthspan.com/DrStephanie and use code DrStephanie15 to get 15% off of your order.

BIOPTIMIZERS MAGNESIUM BREAKTHROUGH

If you want to get all your magnesium in one supplement, you will love Magnesium Breakthrough. Each supplement itself is 500 milligrams of magnesium, which I feel is such a great dosage as a great baseline for most women. So head on over to https://bioptimizers.com/better and use code BETTER for 10% off of any order, but make sure that the magnesium breakthrough is in your cart.

Ashleigh VanHouten gives us a deep dive into the world of muscle science and nutrition for women. Along with Dr. Stephanie, she explores the intricacies of muscle hypertrophy, shedding light on topics such as simultaneous muscle building and fat loss, bulking and cutting strategies, and the importance of progressive overload. Whether you're a seasoned weight trainer or just starting your fitness journey, this conversation promises to dismantle myths and provide invaluable insights for maximizing strength and vitality.

Episode Overview:
0:00 Intro/Teaser
1:20 Exploring Muscle Science for Women
2:12 Focus on Muscle Building and Nutrition
3:43 Prioritizing Muscle Contraction and Effort
6:56 The Importance of Time Under Tension
13:09 Manipulating Time Under Tension
16:11 The Benefits of Filming Workouts
22:05 Balancing Full Range of Motion and Partial Reps
24:50 Understanding Body Mechanics in Training
30:59 Coaching and Foundation
32:49 Consistency and Foundations
34:24 Foundational Movement Patterns
36:06 Initial Assessment and Movements
36:39 Impact of Injury in Fitness
37:39 Injury Prevention and Importance
41:35 Long-Term Impact of Injury
44:33 Modifying Workouts When Injured
50:28 Consequences of Undernourishing
55:05 Nutrition and Safety Signal
58:57 Misconceptions in the Fitness Industry

Resources Mentioned:
Effects of Unilateral Eccentric versus Concentric Training of Nonimmobilized Arm during Immobilization - https://journals.lww.com/acsm-msse/fulltext/2023/07000/effects_of_unilateral_eccentric_versus_concentric.8.aspx
Build Muscle Faster with Kaatsu Training - https://youtu.be/r2lC6a648F8?si=gE3_0Ccnhbz92xzd
Ashley’s books - https://ashleighvanhouten.com/collections/my-book
Chicken LIver Mousse - https://ashleighvanhouten.com/blogs/news/chicken-liver-mousse-recipe
Muscle Science for Women (featuring Dr. Stephanie) - https://podcasts.apple.com/podcast/ep-45-fitness-in-your-40s-and-beyond-dr-stephanie-estima/id592596408?i=1000633181161

Bio:
Ashleigh is a health coach, speaker, podcast host, and author of one of the only nose-to-tail, organ-meat-centric cookbooks in existence, called It Takes Guts. Her new book is called Carnivore-ish. She created and co-hosts the Muscle Science for Women podcast, downloaded more than two million times, where she interviews some of the leading minds in exercise and nutrition methodology and overall wellness and discusses topics relevant to health and muscle building.

We are grateful to our sponsors:

BODYBIO

Fish Oil Plus, alongside the balance oil, are the two oils that I use for myself and my family on a daily basis. We take it straight up with a tablespoon, but it also mixes really well into smoothies and you can also drizzle it over your salad. Head over to https://bodybio.com/better and use code better at checkout to get 15% off your first order.

FATTY15

Essential fatty acids create better skin, hair, nails, repair age-related damage to cells, and activate pathways that regulate sleep and mood. You can get an additional 15% off of their 90-day subscription starter kit if you go to https://fatty15.com/better and use code BETTER at checkout.

BON CHARGE (face mask)

I am doubling down on this year for my best skin ever. The Bon Charge Red Light Face Mask helps with glowing, younger, firmer-looking skin with minimal effort or time AND without really changing your usual day or night routine. Head over to https://boncharge.com/better and use the discount code BETTER at checkout to get 15% off your entire cart.

Menopause expert, Dr. Mary Claire Haver, a board-certified OB/GYN and certified menopause specialist joins Dr. Stephanie in this episode. From debunking fallacies from the Women's Health Initiative to discussing various hormone therapy options, including estrogen, progesterone, and different delivery methods, this episode equips listeners with essential knowledge. Whether you're experiencing perimenopausal symptoms or contemplating hormone therapy as a preventative measure, Dr. Haver provides valuable insights and actionable tips.

This episode will give you a comprehensive understanding of menopause hormone therapy and empower yourself or the women you love with the information needed to make informed decisions about their health.

Episode Overview:

0:00 Teaser/Intro
1:22 Signs of Perimenopause
3:00 In-Depth Symptom Analysis
11:08 Evolutionary Advantages of Menopause
18:45 Menopause Hormone Therapy
30:01 Hormone Therapy Benefits in Menopause
36:34 Hormone Therapy Considerations for Menopausal Women
40:11 CIRM as an Option
44:07 Missed the Menopause Boat
47:40 Magnesium: The Forgotten Nutrient
51:17 Prioritize Good Nutrition
55:36 Protein-Centric Approach
1:01:37 Family History: No Disqualifications
1:04:22 Avoid Injury with Weight Training
1:06:52 Hormone Therapy Side Effects
1:09:00 Future of Menopause Therapy

Resources mentioned in the episode:

Dr. Haver’s new book - https://thepauselife.com/en-ca/pages/the-new-menopause-book

Episode on Women’s Health Initiative - https://drstephanieestima.com/podcasts/hrt-bioidenticals-menopause-benefits-risks/

How Does Menopause Change Your Brain? A Deep Dive with Dr. Lisa Mosconi - https://drstephanieestima.com/podcasts/how-does-menopause-change-your-brain-a-deep-dive/

https://www.menopause.org

https://www.felixforyou.ca/ailment/menopause

Bio:

Dr. Mary Claire Haver is board certified in Obstetrics and Gynecology and is a Certified Culinary Medicine Specialist from Tulane University. She is a Louisiana State University Medical Center graduate and completed her Obstetrics and Gynecology residency at the University of Texas Medical Branch (UTMB). She is also a Certified Menopause Specialist through The Menopause Society. Find out more at https://thepauselife.com/ and Instagram - https://www.instagram.com/drmaryclaire/

We are grateful to our sponsors:

SUNLIGHTEN

I am incredibly bullish on sauna as a therapy for recovery, heart health, and overall aging well. It's crucial for hormonal balance and achieving a state of well-being necessary for a strong physique and a strong mind. Visit https://www.sunlighten.com/BETTER/?utm_source=DrStephanieEstima&utm_medium=Partner&leadsource=DrStephanieEstima&utm_campaign=DrStephanieEstima and use code BETTER to get a discount.

EQUIP FOODS

You can use this grass-fed collagen daily, to take care of your hair, skin, nails, joints, and gut after resistance training workouts, or you can even bake with it because it tastes like dessert, not beef. Go to https://equipfoods.com/better and use the code BETTER for 20% off.

ONESKIN

It’s time for a radical shift in skin care. This year I am doubling down on skin health and OneSkin is one of the ways I am getting my 40-year-old skin to behave like 20-year-old skin. Visit https://www.oneskin.co/?utm_source=partner&utm_medium=podcast&utm_campaign=BETTER and use the code BETTER at checkout to save 15%.

Dr. Donald Layman is the OG in the field of protein and amino acids. Dr. Layman's expertise spans decades, and his insights have revolutionized our understanding of protein's role in health, from athletic performance to combating obesity, diabetes, and cardiovascular issues.

In this episode, Dr. Layman teaches you about the nuances between protein intake and amino acids, shedding light on the essential nine and synthesizable eleven amino acids crucial for our diets. Delving further, he and Dr. Stephanie explore the intricacies of protein quality, comparing animal and plant-based sources, and deciphering the optimal dosing for muscle growth and repair.

Don also unravels the mysteries surrounding carbohydrate load tolerance, navigating the fine balance between minimum and maximum carbohydrate intake for various training regimens. Additionally, they debunk myths surrounding aging, particularly in women, and the imperative role of protein consumption in perimenopause and menopause.

Episode Overview:
0:00 Intro/Teaser
3:36 Welcome Dr. Donald Layman
4:13 Exploring the Function of Muscle in the Body
11:43 Delving into Protein, Amino Acids, and Synthesis
15:07 Protein Needs and Aging Process
26:58 Protein Quality: Animal vs. Plant Proteins
34:01 Supporting Vegetarians and Vegans with Protein Intake
36:16 Child Neglect and Malnutrition
41:00 Regulation of mTOR and Carbohydrate Consumption
44:22 Muscle Potential and DNA Limits
54:07 Leucine, mTOR, and MPS
57:44 Protein Timing for Exercise
1:00:30 Carbohydrates and Protein Choices
1:03:58 Protein Target for Weight Loss
1:07:54 Protein Dosing Throughout the Day

Resources Mentioned:
Essential amino acids and muscle protein recovery from resistance exercise - https://journals.physiology.org/doi/pdf/10.1152/ajpendo.00466.2001
Metabolic Flux - https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/metabolic-flux
Exercise, protein metabolism, and muscle growth - https://pubmed.ncbi.nlm.nih.gov/11255140/
Stimulation of net muscle protein synthesis by whey protein ingestion before and after exercise - https://pubmed.ncbi.nlm.nih.gov/16896166/
Dietary protein distribution positively influences 24-h muscle protein synthesis in healthy adults - https://pubmed.ncbi.nlm.nih.gov/24477298/
Website: MetabolicTransformation.com
Forever Strong book - https://drgabriellelyon.com/forever-strong/

Bio:
Dr. Donald Layman is Professor Emeritus in the Department of Food Science & Human Nutrition at the University of Illinois at Urbana-Champaign. Dr. Layman served on the faculty at the University of Illinois from 1977 – 2012. Dr. Layman has been a leader in research about protein, nutrition for athletic performance, obesity, diabetes and cardiovascular health. Dr. Layman has over 120 peer-reviewed publications. He has received numerous awards for his research from the American Society for Nutrition and the National Institutes for Health and for his nutrition teaching. Dr. Layman served as Associate Editor of The Journal of Nutrition and the Journal of Nutrition Education and Behavior and on the editorial boards of Nutrition & Metabolism and Nutrition Research and Practice. Dr. Layman has an extensive consulting background including work with NASA, the Shriners Children’s Hospital, the US Air Force plus numerous food companies and organizations including Kraft Foods, Nestlé, Danone, Agropur, the American Egg Board, and the National Dairy Council. Dr. Layman earned his B.S. and M.S. degrees in chemistry and biochemistry at Illinois State University and his doctorate in human nutrition and biochemistry at the University of Minnesota.

We are grateful to our sponsors:

BODYBIO
BodyBio PC is a liposomal phospholipid complex designed to nourish your cells for healthy aging, optimal brain function, gut health, a better metabolism, and more. Prioritizing your cellular health is absolutely foundational for your well-being as you age. You can get started and save 15% off your first order with code BETTER at checkout at https://bodybio.com/BETTER

TIMELINE
Feeling tired and having no energy does not have to be your fate. Mitopure is a supplement and skin health line that helps improve energy at the level of the mitochondria so that you can continue to engage in the activities you love. Go to https://timelinenutrition.com/better and use code BETTER to get 10% off your order.

BIOPTIMIZERS
If you want to get all your magnesium in one supplement, you will love Magnesium Breakthrough. Each supplement itself is 500 milligrams of magnesium, which I feel is such a great dosage as a great baseline for most women. So head on over to https://bioptimizers.com/better and use code BETTER for 10% off of any order, but make sure that the magnesium breakthrough is in your cart.

Biohacking expert Aggie Lal joins this episode for a dynamic conversation about cycle syncing for women's health. With Dr. Stephanie's expertise in nutrition and Aggie's comprehensive approach to biohacking, they delve into topics ranging from menstrual cycle variations to stress management techniques.

Explore how nutrition, fasting, and training can be tailored to different phases of the menstrual cycle, and gain insights into emotional fluctuations and stress mitigation strategies. Whether you're a seasoned health enthusiast or new to the concept, this episode offers invaluable tips for optimizing wellness through cycle syncing.
Episode Overview
1:17 - Introducing Biohacking Bestie, Aggie Lal
2:43 - The Role of Women in Biohacking
6:59 - Embracing Feminine Energy
8:27 - Feminine Energy in Strength Training
14:11 - Shifting from Skinny to Strong1
4:14 - Lifting Weights and Cycle Training
19:02 - Training According to Menstrual Cycle
27:16 - Fasting Framework for Women
31:13 - Importance of Auto-Regulation in Health and Fitness
35:30 - Breaking Free from Masculine Ideals
36:51 - Embracing Femininity and Lifestyle Balance
37:20 - Period Power Beyond Reproduction
44:06 - Microfasts and Eating Patterns
44:37 - Nutrition, Metabolism, and Stress Management
51:43 - The Healing Power of Forgiveness
56:48 - Embracing Play and Pleasure
1:02:20 - The Teacher-Student Energetic Shift

Bio:
Aggie Lal is a renowned public figure, best-selling author, certified nutrition and health coach, podcast host, TV personality, and TEDx speaker. With more than 1.5 million social media followers and a vast audience across multiple channels, Aggie has become highly influential in the areas of health, biohacking, personal development, entrepreneurship, and travel & lifestyle. Find out more at https://biohackingbestie.com/

Resources Mentioned:

https://biohackingbestie.com/products/biohack-like-a-woman

https://higherselfacademy.co/

Insights into Dr. D’Agostino’s 72-hour fasting experience - https://ketonutrition.org/insights-into-dr-dagostinos-72-hour-fasting-experience/

40 Years of Zen - https://40yearsofzen.com/

We are grateful to our sponsors:

TIMELINE

Feeling tired and having no energy does not have to be your fate. Mitopure is a supplement and skin health line that helps improve energy at the level of the mitochondria so that you can continue to engage in the activities you love. Go to https://timelinenutrition.com/better and use code BETTER to get 10% off your order.

NEUROHACKER

High NAD levels help our bodies by creating energy, maintaining healthy DNA, and protecting our cellular health. You can try Qualia NAD risk-free for 100 days by going to https://neurohacker.com/better and use the code BETTER at checkout to get 15% off of your order.

BEAM MINERALS

Cold plunges are so useful for muscle healing and recovery, which is why they're so good when they're done on the same day as a workout. But if your mineral stores are low, you're not going to get the full recovery benefits that a cold plunge might offer. So next time you're doing your cold plunge take a Beam Mineral shot for an extra boost. Head over to https://beamminerals.com and use the code BETTER at checkout to save 20% off of your first order.

Jessica Berman, the Chief Marketing Officer of BodyBio, delves into the fascinating world of seed oils, omega-6s, omega-3s, and their impact on our bodies' composition and overall health.

In this episode, Jessica and Dr. Stephanie journey through the scientific landscape, dissecting terms like linoleic acid and ALA, and debunking myths surrounding the vilification of seed oils.

Moving beyond the surface, they also explore the role of butyrate, its activation of GLP-1 agonists, and its profound implications for weight loss and body composition. Jessica sheds light on how the fatty acid needs of women evolve during pivotal life stages like perimenopause, pregnancy, childbirth, and breastfeeding.

Episode Overview:
0:00 Intro/Teaser
2:28 Butyrate and GLP-1 Agonists
3:21 Brain Health and Perimenopause
10:03 Essential Fatty Acids Pathway
10:51 Nuanced Conversation on Seed Oils
13:05 Scientific Illiteracy on Social Media
15:21 Evening Primrose Oil Benefits
17:04 Omega-3 Precursor ALA
17:48 Importance of EPA and DHA
19:03 The Balance of Essential Fatty Acids
20:01 Caviar as a Source of EPA and DHA
21:04 Phospholipid Form of Fish Oil
23:01 Liposomal Delivery and Absorption
24:31 Omega Fatty Acids and Health
27:55 Women's Health in Perimenopause
31:07 Changes in Linoleic Acid Concentration
32:38 Importance of Phosphatidylcholine in Detoxification
34:21 Detoxing from Mold Exposure
36:53 Clearing Mold Toxins with Essential Fatty Acids
37:56 Impact of Essential Fatty Acids on Behavior
39:34 Benefits of Essential Fatty Acids for Kids
42:02 Therapeutic Dosing of Essential Nutrients
46:54 Resistant Starches and Butyrate Production
48:11 Butyrate in Colon Health and Immune Function
51:47 Butyrate for GI Health and Inflammation
54:16 Using Essential Fatty Acids for Long COVID
58:23 Therapeutic Dosage for Mold Recovery
1:01:52 Where to Find BodyBio Products

Bio:
As the CMO of BodyBio, Jess leads all internal and external efforts in building the BodyBio brand and footprint across all social channels and expanding distribution both in the U.S. and internationally with the company’s trusted partners. In the last few years alone, Jess and her team have successfully managed consumer-driven marketing campaigns that have collectively generated over 55MM digital impressions across all social channels in the last 24 months. Jess has also been instrumental in securing partnerships with leading medical doctors and functional medicine specialists all of whom have endorsed BodyBio recommending its line of products to their patient network.

Resources mentioned:
BodyBio - https://bodybio.com/BETTER
Dietary linoleic acid and risk of coronary heart disease: a systematic review and meta-analysis of prospective cohort studies - https://pubmed.ncbi.nlm.nih.gov/25161045/
Jennifer Fisher Kitchen - https://www.instagram.com/jenniferfisherkitchen/
A banana a day could keep cancer at bay - https://www.leeds.ac.uk/news-health/news/article/5128/a-banana-a-day-could-keep-cancer-at-bay

We are grateful to our sponsors:

SUNLIGHTEN

I am incredibly bullish on sauna as a therapy for recovery, heart health, and overall aging well. It's crucial for hormonal balance and achieving a state of well-being necessary for a strong physique and a strong mind. Visit https://www.sunlighten.com/BETTER/?utm_source=DrStephanieEstima&utm_medium=Partner&leadsource=DrStephanieEstima&utm_campaign=DrStephanieEstima and use code BETTER to get a discount.

BODYBIO

BodyBio PC is a liposomal phospholipid complex designed to nourish your cells for healthy aging, optimal brain function, gut health, a better metabolism, and more. Prioritizing your cellular health is absolutely foundational for your well-being as you age. You can get started and save 15% off your first order with code BETTER at checkout at https://bodybio.com/BETTER

ONESKIN

It’s time for a radical shift in skin care. This year I am doubling down on skin health and OneSkin is one of the ways I am getting my 40-year-old skin to behave like 20-year-old skin. Visit https://www.oneskin.co/?utm_source=partner&utm_medium=podcast&utm_campaign=BETTER and use the code BETTER at checkout to save 15%.

Carolina Reis Oliveira’s journey is as impressive as her expertise in skin care. In this episode, she dives deep into the science of skin aging. Along with Dr. Stephanie, she explores and explains both intrinsic and extrinsic factors, from cellular processes to environmental exposures. Carolina also shares insights into inflammation, peptide therapy, and the transformative potential of innovative compounds like OS-01.

OneSkin is getting to the root cause of skin aging with OS-01, a novel peptide that targets cellular senescence. OS1 influences cellular repair pathways and increases epidermal thickness. Explore face and body products at https://www.oneskin.co?utm_source=partner&utm_medium=podcast&utm_campaign=BETTER and use code BETTER at checkout to save 15%.

Drawing from her team's research, Carolina discusses tangible results in reducing skin aging, offering hope for conditions like hyperpigmentation and rosacea. We explore strategies to stay ahead of the aging curve, aiming for what Carolina calls "escape velocity"—a state where we not only halt aging but reverse its effects.

Episode Overview:
0:00 Intro/Teaser
0:01:29 Interview with Carolina Oliveira
0:03:10 Skin Aging Mechanisms and Peptide Therapy
0:04:28 Intrinsic Mechanisms of Skin Aging
0:08:21 Intrinsic Aging Factors and Genetics
0:10:15 Cellular Senescence and Aging
0:13:11 Autophagy and Aging
0:14:37 Xenomorphic vs. Senolytic Compounds
0:16:18 Discovery of OS1 Peptide
0:19:12 Safety and Validation of OS1 Peptide
0:20:53 Human Clinical Studies on OS1 Peptide
0:25:00 Effects of OS1 on Skin Health
0:29:31 Specific Formulations for Eye Cream
0:31:01 Tailored Skincare for Different Areas of Body
0:36:39 The Science of Hyperpigmentation and Skincare
0:40:14 Combining Acids, Peptides, and Skincare
0:44:15 Consumer Awareness and Integrity in Skincare
0:47:57 The Importance of Antioxidants in Skincare
0:51:52 The Future of Skincare: Lip Treatments
0:53:43 Innovations in Sunscreen Technology
0:56:53 Prioritizing Skin Health Over Immediate Results
0:59:26 Maintaining Integrity in the Skincare Industry

Bio:
Carolina Oliveira, CEO and co-founder of OneSkin. Holds a Ph.D. in stem cell biology and tissue engineering, is a co-inventor of 5 patents and co-author of numerous scientific publications. She relocated from Brazil to Silicon Valley in 2016 to found OneSkin, a fast-growing longevity company developing products to promote skin age reversal by targeting a central driver of aging, the accumulation of senescent cells. Carolina and her team are disrupting the outdated anti-aging skincare industry with their groundbreaking research around skin and longevity.

Resources mentioned:

OneSkin: https://www.oneskin.co/ and use code BETTER at checkout to save 15%.

About Carolina Reis Oliveira, Ph.D.: https://www.oneskin.co/pages/our-story

The science: https://www.oneskin.co/pages/science and https://www.oneskin.co/pages/publications

We are grateful to our sponsors:

EMBR

I absolutely love this for my perimenopausal and menopausal women who are experiencing hot flashes and then the shivering that happens afterward. Go to https://embrlabs.com/products/embr-wave-2?rfsn=7896910.951991&discount/DRSTEPHANIE?redirect=/products/embr-wave-2 and use DRSTEPHANIE for 15% off of the Ember Wave 2. It is a bracelet (I got it in rose gold) and I love it.

FATTY15

Essential fatty acids create better skin, hair, nails, repair age-related damage to cells, and activate pathways that regulate sleep and mood. You can get an additional 15% off of their 90-day subscription starter kit if you go to https://fatty15.com/better and use code BETTER at checkout.

BIOPTIMIZERS

If you want to get all your magnesium in one supplement, you will love Magnesium Breakthrough. Each supplement itself is 500 milligrams of magnesium, which I feel is such a great dosage as a great baseline for most women. So head on over to https://bioptimizers.com/better and use code BETTER for 10% off of any order, but make sure that the magnesium breakthrough is in your cart.