Showing titles in Genetics

The language of genes has become common parlance. We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise. So we've all heard of genes, but how do they actually work?

In 2010, scientists led by J. Craig Venter became the first to successfully create "synthetic life" - putting humankind at the threshold of the most important and exciting phase of biological research, one that will enable us to actually write the genetic code for designing new species to help us adapt and evolve for long-term survival. The science of synthetic genomics will have a profound impact on human existence, including chemical and energy generation, health, clean water and food production, environmental control, and possibly even our evolution.

Unravelling the Double Helix covers the most colourful period in the history of DNA, from the discovery of 'nuclein' in the late 1860s to the publication of Watson's The Double Helix in 1968. This is a saga packed with awful mistakes as well as brilliant science, with a wonderful cast of heroes and villains. Surprisingly, much of it is unfamiliar because the early history is largely neglected by books which focus on the episode of the double helix.

How is it that Homo sapiens formed such a special relationship with what, on the face of it, is a most unlikely ally? It is more than just a story of domestication but an astonishing example of the co-evolution of two species, man and wolf, to each other's mutual benefit. This co-evolution was a vital step in helping Homo sapiens overcome competition from other human species and to expand in numbers from relative obscurity on the margins towards the overwhelming numerical superiority and influence that we enjoy today.

In Valley of Forgetting, Jennie Erin Smith brings listeners into the clinic, the laboratories, and the Medellín trial center where Lopera’s patients receive an experimental drug to see if Alzheimer’s can be averted. She chronicles the lives of people who care for sick parents, spouses, and siblings, all while struggling to keep their own dreams afloat.

Orphan is about the struggle to save the lives of children who, because of an unlucky roll of the genetic dice, are born with any one of several thousand rare genetic disorders. Many are burdened with diseases that carry mysterious names, some of which you will hear about for the first time in this audiobook, along with compelling stories about the physicians, scientists, and parents who have taken them on.

Today, with relatively easy access to our DNA ancestry, we have more data about ourselves and family history than previous generations could have imagined. In the 12 fascinating lessons of Identity in the Age of Ancestral DNA, Anita Foeman, PhD, professor of communication and media, and founder and primary investigator of the DNA Discussion Project at West Chester University, takes us behind the scenes to examine what really happens when individuals receive their personal DNA ancestry results.

Vital research is starting to challenge long-standing assumptions about gender identity and biological sex, such as work that indicates the brain is a “mosaic” of traits rather than a “male” and “female” brain. Growing knowledge of the genetic complexities of sexual determination is changing the way the medical community treats intersex individuals, and in this audiobook, The New Science of Sex and Gender, we not only examine the latest studies in biology, medicine, and psychology but also, more importantly, their bearing on healthcare, identity, and access.

Around 250,000 people have had their genomes sequenced, and scientists expect that number to rise to one billion by 2025. Professor Steven J. Heine argues that the first thing we will do on receiving our DNA test results is to misinterpret them completely. Despite breathless (often lightly researched) media coverage about newly discovered "cancer" or "divorce" or "IQ" genes, the prospect of a DNA test forecasting how your life is going to turn out is vanishingly small.

A panoramic overview of biotechnologies that can endlessly boost human capabilities and the drastic changes these "superhuman" traits could trigger. Biotechnology is moving fast. In the coming decades, advanced pharmaceuticals, bioelectronics, and genetic interventions will be used not only to heal the sick but to boost human physical and mental performance to unprecedented levels.

In Strange Bedfellows, David P. Barash and Judith Eve Lipton look at how biology actually promotes monogamy in some species and how these lessons apply to human beings. An accessible work of science that is relevant to our intimate daily life, Strange Bedfellows will reassure some people, surprise others, and engage everyone.

The emergence of genomic science in the last quarter century has revolutionized medicine, the justice system, and our understanding of who we are. We use genomics to determine guilt and exonerate the falsely convicted; devise new medicines; test embryos; and discover our ethnic and national roots. One might think that, given these advances, most would favor the availability of genomic tools. Yet as Jennifer Hochschild explains in Genomic Politics, the uses of genomic science are both politically charged and hotly contested.

From the author of Seed of Israel: DNA Guide to Tracing Your Jewish Ancestry comes this great dive into the history of Ashkenazi Jews. While controversial debates spark disagreements on the crystallization of this Jewish Diaspora, modern genetic studies and personal DNA samples finally conclude the Levantine Middle Eastern and Mediterranean roots of Ashkenazi ancestry: Judean people from the Holy Land that journeyed across the Mediterranean to the bottleneck of Europe.

Delve deeper into the scientific terms and theories at the core of the Peabody-winning, cult favorite show. With exclusive insights from the show's cocreator, Graeme Manson, and science consultant Cosima Herter, The Science of Orphan Black takes you behind the closed doors of the Dyad Institute and inside Neolution.

Want to know what exercises are proven to make you gain muscle and strength? Then this book is perfect for you! It tells you the 48 best gym exercises for building strength and gaining muscle. I have included all important muscle groups (Chest, Back, Legs, Arms, Shoulders/Neck, Abs). Many of them are timeless and have been performed by bodybuilders for decades. They are proven to work, and should be part of every workout routine. No fluff or bro science! No need for fancy equipment or a personal trainer.

In this fascinating exploration, geneticist Bryan Sykes turns his sights on the United States, one of the most genetically variegated countries in the world. From the blue-blooded pockets of old-WASP New England to the vast tribal lands of the Navajo, Bryan Sykes takes us on a historical genetic tour, interviewing genealogists, geneticists, anthropologists, and everyday Americans with compelling ancestral stories.

Po Bronson and Arvind Gupta, venture capitalists from Silicon Valley, take everyday news headlines and decode them, leading us on a journey through their unique and highly entertaining view of the world. Each chapter is prefaced with a real-world headline from today's chaotic news cycle: dying bees. Rogue planets. Beyond Meat. Glaciers melting. Bronson and Gupta decipher what's really going on behind these headlines, and why.

First there was the genetic revolution—the discovery that physical structures in the cell, including DNA and RNA, shape every organism. Now, says evolutionary biologist Richard Sternberg, we are overdue for another and more profound revolution. Recent findings reveal that genetic and even epigenetic sources alone cannot account for the rich dynamism of life—not even close. Some other informational source is required.

In this exploration of the concept of the gene, Jonathan Slack looks at the discovery, nature, and role of genes in both evolution and development. Explaining the nature of genetic variation in the human population, how hereditary factors were identified as molecules of DNA, and how certain specific mutations can lead to disease, Slack highlights how DNA variants are used to trace human ancestry and migration, and can also be used by forensic scientists to identify individuals in crime.

While traditional drugs mostly help us manage the effects of disease, cell therapies promise genuine cures for a broad range of intractable ailments, from Alzheimer’s to heart damage to cancer. They could even reverse the effects of aging. For the first time in history, on an unprecedented scale, we possess the power to modify the biology that gives rise to disease, ultimately restoring individuals to a state of normalcy and reversing debilitating ailments. Former FDA Commissioner Scott Gottlieb traces the scientific achievements that propelled progress in cell therapies.