Is Ubiquinol the Missing Nutrient for Lifelong Heart Health?

In this eye-opening episode of Wellness by Designs, Dr Ross Walker, a renowned cardiologist with 25 years dedicated to preventative medicine, challenges the conventional approach to heart disease, statins and cholesterol management. Central to the discussion is ubiquinol, the active form of CoQ10, essential for mitochondrial energy production and a powerful antioxidant. Dr Walker explains how our natural production of ubiquinol begins declining around age 30 and drops sharply by 50, contributing to fatigue and reduced cardiovascular resilience.

Dr Walker explores why many patients with “normal” cholesterol still develop significant coronary artery disease, arguing that coronary calcium scoring offers a far superior risk assessment tool than standard cholesterol tests. Dr Walker also addresses statin-associated muscle symptoms, recommending 150 mg of ubiquinol daily for statin users, citing research showing a 50% reduction in muscle problems, and up to 300 mg for those with heart failure to support cardiac function and endothelial health.

From mitochondrial health to protection against oxidative stress, this episode highlights why ubiquinol may be a cornerstone in maintaining cardiovascular wellness and why a more personalised, evidence-based approach is needed to truly prevent heart disease.

Connect with Dr Walker: Home - Dr Ross Walker

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DISCLAIMER: The Information provided in the Wellness by Designs podcast is for educational purposes only; the information presented is not intended to be used as medical advice; please seek the advice of a qualified healthcare professional if what you have heard here today raises questions or concerns relating to your health

Is it time to rethink how we treat atopic dermatitis?

Atopic dermatitis is more than skin deep—and naturopath and award-winning clinician Rebecca Hughes is here to prove it. In this practical and insightful episode, Rebecca shares her integrative, root-cause approach to eczema that goes far beyond suppressing symptoms with topical steroids.

Drawing from extensive clinical experience, Rebecca highlights the importance of accurate diagnosis, noting that conditions such as psoriasis, seborrheic dermatitis, and lupus are often misidentified as eczema—leading to ineffective treatment. She walks practitioners through key investigations, from food intolerance and intestinal permeability testing to genetic susceptibilities, that help identify true inflammatory drivers.

Rebecca also outlines her foundational nutrient protocol, including zinc, vitamin D, vitamin A, quercetin, and glutamine, and discusses how these work synergistically to modulate immune response, stabilise mast cells, and repair gut integrity. She also addresses overlooked environmental triggers like mould and water-damaged buildings, as well as the clinical importance of emotional support, sleep hygiene, and managing the psychological toll of visible skin conditions.

Clinicians will find practical strategies for supporting patients through topical steroid withdrawal, tips on using bleach baths safely for Staphylococcus aureus overgrowth, and why children with eczema require particularly vigilant care.

With a soon-to-be-released practitioner course on atopic dermatitis, Rebecca equips healthcare professionals with the tools they need to treat this complex condition confidently and holistically.

Connect with Rebecca: Home - Rebecca Hughes Naturopath

Explore Rebecca's Managing Atopic Dermatitis Course: Use code SAVE30 for a 30% discount. More information on the course can be found here: Managing Atopic Dermatitis | Natural Skin Medicine Courses

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DISCLAIMER: The Information provided in the Wellness by Designs podcast is for educational purposes only; the information presented is not intended to be used as medical advice; please seek the advice of a qualified healthcare professional if what you have heard here today raises questions or concerns relating to your health

Why These Drugs Aren’t Magic Bullets—And How to Maximise Their Clinical Impact

The sharp rise in GLP-1 agonist prescriptions – up over 42% in Australia since 2019 – is reshaping how we approach weight loss and metabolic health. But are we ready to support patients beyond the script?

In this evidence-informed episode, dietitian and exercise scientist Robbie Clark joins us to unpack the clinical realities of GLP-1 medications like Ozempic® and Wegovy®. Far from being quick fixes, these medications work best when combined with targeted nutrition, resistance training, and gut support.

Robbie explores how GLP-1 agonists enhance insulin secretion, suppress appetite, and deliver cardiovascular benefits, while sharing practical strategies to enhance patient outcomes and minimise side effects. From optimising protein intake (1.2–1.6 g/kg) to prevent muscle loss, to managing nausea and reflux, you’ll gain the tools to confidently guide your patients through every stage of their GLP-1 journey.

We also dive into the surprising science of bitter foods – like dandelion, grapefruit, and dark chocolate – that naturally stimulate GLP-1 receptors, offering a food-first support strategy that complements medication.

Perhaps most crucial is the discussion on weight regain post-discontinuation, with studies showing 60–100% of lost weight can return within a year without lifestyle foundations. Robbie provides realistic, sustainable strategies to help patients move from medication reliance to long-term metabolic resilience.

Whether you’re currently supporting patients on GLP-1 medications or preparing for their growing use in practice, this episode delivers the clinical insights you need to turn short-term interventions into lasting lifestyle change

Connect with Robbie: healthbank.io

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DISCLAIMER: The Information provided in the Wellness by Designs podcast is for educational purposes only; the information presented is not intended to be used as medical advice; please seek the advice of a qualified healthcare professional if what you have heard here today raises questions or concerns relating to your health

Why Women Are More Vulnerable—and What You Can Do Clinically

Could histamine intolerance be the hidden driver behind your patient’s anxiety, bloating, headaches, or skin flares? In this episode, nutritionist and epigenetics expert Zelda Graham breaks down the complex interplay between histamine, methylation dysfunction, gut health, and hormonal imbalances—especially in women.

You’ll gain critical insights into the role of DAO and HNMT enzymes, estrogen’s impact on histamine load, and why symptoms often worsen during ovulation and perimenopause.

Zelda also shares clinical strategies to identify and address root causes like mould exposure, gut dysbiosis, and methylation SNPS—plus targeted therapies using nutrients like quercetin, NAC, liposomal glutathione, and calcium D-glucarate.

This episode is essential listening for practitioners managing complex, multisystem female presentations—from hormone imbalances to unresolved histamine-related inflammation.

Connect with Zelda:

Website: www.byronhealthandnutrition.com

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DISCLAIMER: The Information provided in the Wellness by Designs podcast is for educational purposes only; the information presented is not intended to be used as medical advice; please seek the advice of a qualified healthcare professional if what you have heard here today raises questions or concerns relating to your health

Gut Health, Food as Medicine, and the Power of Simplicity with Lee Holmes

Clinical nutritionist Lee Holmes shares her personal journey from Crohn’s disease and fibromyalgia to vibrant health—and how gut healing became the foundation of her clinical philosophy.

In this heartfelt and practical episode, Lee explores the therapeutic power of whole foods, the impact of stress on the microbiome, and why gentle, digestible nutrition is often the most powerful intervention.

Practitioners will gain insights into restoring microbial balance, supporting gut lining integrity, and helping patients adopt sustainable habits without triggering restriction or anxiety.

From prebiotic-rich foods to the importance of mindful eating and family meals, this conversation offers a refreshing, real-world approach to digestive healing—grounded in both evidence and compassion.

Connect with Lee: Supercharged Food – Supercharged Food, gluten, sugar and dairy free anti-inflammatory recipes to heal

Discover Lee's latest books: Bookshelf – Supercharged Food

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DISCLAIMER: The Information provided in the Wellness by Designs podcast is for educational purposes only; the information presented is not intended to be used as medical advice; please seek the advice of a qualified healthcare professional if what you have heard here today raises questions or concerns relating to your health

Metabolic Endotoxemia: The Gut–Gut-Inflammation Link You Can’t Ignore!

Could chronic, low-grade inflammation be rooted in your patient’s gut? In this compelling episode, naturopath Steven Judge unpacks the emerging science of metabolic endotoxemia—where bacterial endotoxins (LPS) escape a compromised gut barrier and trigger systemic immune responses linked to cardiovascular disease, insulin resistance, endometriosis, and more.

You'll gain a deeper understanding of intestinal hyperpermeability, toll-like receptor activation, and how to identify root causes like stress, toxin exposure, and circadian disruption.

Steven also shares evidence-based tools—including omega-3s, polyphenols, PEA, and bovine immunoglobulins—to help reduce the inflammatory load and support long-term gut healing.

This episode is a must-listen for practitioners wanting to connect ancient gut wisdom with today’s cutting-edge clinical practice.

Connect with Steven: Steven Judge Clinical Naturopathy

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DISCLAIMER: The Information provided in the Wellness by Designs podcast is for educational purposes only; the information presented is not intended to be used as medical advice; please seek the advice of a qualified healthcare professional if what you have heard here today raises questions or concerns relating to your health

Naturopath Anthia Koullouros explores the nervous system's critical role in healing and why repositioning from chronic stress into a regulated state creates the foundation for addressing persistent health issues.

Highlights from this episode:
• Understanding the four stress responses: fight, flight, freeze, and fawn
• How chronic stress directly prevents healing by prioritising survival mechanisms over repair
• Recognising when your nervous system is stuck in protective mode without your awareness
• The physiological impacts of stress responses on heart rate, breathing, digestion, and sleep
• Simple but effective first-aid techniques to create nervous system regulation
• Using nutritional support, adaptogens, and nervine herbs to create capacity for deeper healing
• The importance of meeting negative thoughts with curiosity rather than suppression
• Developing nervous system flexibility as the true marker of wellbeing

"When you love enough of something that you're taking care of, it'll love you back. When you pay it attention, it'll pay you attention back."

Connect with Anthia: Apotheca by Anthia

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DISCLAIMER: The Information provided in the Wellness by Designs podcast is for educational purposes only; the information presented is not intended to be used as medical advice; please seek the advice of a qualified healthcare professional if what you have heard here today raises questions or concerns relating to your health

In this episode, Dr Brad Leech shares the exclusive results of his PhD research, which produced the first comprehensive clinical practice guidelines for intestinal permeability.

Dispelling common myths about "leaky gut syndrome," Dr Leech explains why intestinal hyperpermeability is a legitimate physiological reaction—not a syndrome—and how his meticulously developed, evidence-based guidelines can transform clinical practice.

This episode provides invaluable insights into the following:

• The rigorous methodology behind developing clinical practice guidelines, including stakeholder engagement, comprehensive literature review, and systematic evaluation of over 10,000 research articles
• The critical importance of risk-of-bias assessment when evaluating research—a cornerstone of methodology that helps practitioners look beyond cherry-picked studies and misleading claims
• How to systematically evaluate research quality by examining randomization procedures, analysis methods, conflict of interests and clinical relevance rather than accepting published findings at face value
• Surprising findings about commonly used interventions in intestinal permeability, including evidence that certain probiotics may not be effective for NSAID-induced permeability despite their widespread recommendation
• Evidence-based assessment of treatments for intestinal permeability using the NHMRC grading matrix to evaluate research quality
• Practical recommendations and evidence-supported interventions that meet the threshold for clinical relevance

Dr Leech's work represents a significant advancement in the field, bringing scientific rigour to an area often clouded by opinion and marketing claims.

Learn how these new guidelines can help you make more informed clinical decisions and improve patient outcomes through evidence-based approaches to intestinal permeability.

Connect with Dr Leech: Dr Brad Leech

Read: The IP Guideline

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DISCLAIMER: The Information provided in the Wellness by Designs podcast is for educational purposes only; the information presented is not intended to be used as medical advice; please seek the advice of a qualified healthcare professional if what you have heard here today raises questions or concerns relating to your health