• Mojo Monday - Anger and Aggression: What You Feel vs What You Do With Carly Taylor
    Nov 23 2025

    We talk so much about managing anger, but what if anger isn’t the real issue at all? In this week’s Mojo Monday, Carly unpacks the crucial difference between anger and aggression, and how understanding that gap can change the way we respond.

    To find out more about Carly, visit www.carlytaylorcoaching.com.au.
    Follow her on Instagram: carly_taylor_coaching

    See omnystudio.com/listener for privacy information.

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    5 mins
  • Are we on the brink of a breakthrough in healthy aging? A masterclass in NAD+, with Dr Charles Brenner
    Nov 21 2025
    If you're interested in optimising your healthspan and lifespan, this episode is not to be missed. In the quest for longevity, the spotlight has turned to NAD+ and its precursors, NMN and NR. In this episode featuring Dr. Charles Brenner, a metabolism scientist, we dive deep into the significance of these molecules and their role in healthy aging. You'll discover that NAD+ (Nicotinamide Adenine Dinucleotide) is not just a trending topic but rather a crucial player in metabolism. Learn why Charles refers to it as the "central jewel of metabolism". In the conversation, the distinction between NMN (Nicotinamide Mononucleotide) and NR (Nicotinamide Riboside) is clarified, and you'll discover which of these molecules has the best evidence-base. You'll also find out why some popular ways to increase NAD+ are an expensive waste of time. Dr. Brenner highlights the importance of evidence-based research, citing eight randomised clinical trials demonstrating the anti-inflammatory effects of one of the NAD+ precursors in humans. One significant study focuses on peripheral artery disease (PAD), a condition affecting millions of older adults that can severely impact mobility and quality of life. Ypu'll also disciver why a simple functional test is a way better predictor of longevity than all of the espoensive epigenetic-focused Biological Age tests that are currently on the market. What You'll Learn: The Basics of NAD and Its Functions: Understand the foundational role of NAD in cellular metabolism and how it acts as a transmitter of high-energy electrons needed for energy production and cell functions.Scientific Evidence and Research: Discover the rigor behind the clinical research of NAD and its supplements, like Nicotinamide Riboside (NR), including ongoing trials and results showing anti-inflammatory properties in humans.Controversies and Misconceptions: Unpack the myths concerning longevity molecules, such as misinterpretations around resveratrol, with arguments laid out by reputable scientists like Dr. Brenner.Applications in Age-Related Diseases: Explore the potential of NR supplements in addressing conditions like peripheral artery disease and its promising though variable outcomes in treating Long COVID and neurodegenerative diseases.Critical Analysis of Clinical Trials: Learn about the importance of clinical integrity, unbiased research, and how independent laboratories contribute to credible scientific discoveries. Key Takeaways: NAD is vital for maintaining metabolic health and managing cellular stress, which is essential for healthy aging.Recent clinical trials have shown promising results for NR in reducing inflammation and improving conditions related to peripheral artery disease.There's ongoing research into NR's benefits for cognitive function, particularly its potential effects on neurodegenerative disease.Supplements should be chosen carefully, preferably ones that have been tested in clinical trials to ensure efficacy and authenticity.The conversation between Dr. Taylor and Dr. Brenner highlights the need to critically evaluate scientific claims, especially those that are widely publicised without robust evidence. Through the episode, Dr. Brenner provides deep insights into how NAD coenzymes operate within the body and why they're considered crucial for longevity research. Moreover, listeners are encouraged to discern meticulously between scientific fact and internet hype, ensuring they make informed decisions when considering supplements. The episode is a valuable resource for anyone interested in the intersection of biochemistry, aging, and healthspan science. Resources Socials: X: @CharlesMBrenner LinkedIn: https://www.linkedin.com/in/charles-brenner/ Support the Podcast If you found this conversation valuable, consider subscribing and leaving a review on your preferred podcast platform. Your feedback helps us continue to bring you insightful discussions on important health topics. 00:11 Understanding NAD+ and Longevity Molecules 01:31 Debunking Longevity Myths 03:02 The Science Behind NAD+ and Metabolism 08:46 Clinical Trials and Evidence 09:37 Peripheral Artery Disease and NAD+ 11:00 Walking Speed as a Health Indicator 13:25 Challenges with DNA Methylation Clocks 21:40 NAD+ in Metabolic Processes 23:48 The Role of NAD in DNA Repair and Cellular Health 24:09 Inflammation and Aging: The Connection 25:20 Human Longevity and Reproductive Capacity 30:02 The Hallmarks of Aging 31:11 Challenges of Living in 2025: Long COVID 31:42 Clinical Trials and NAD Supplements 34:33 The Debate on NMN vs. NR 41:58 Intravenous NAD and Its Efficacy 45:06 NAD's Role in Neurodegenerative Diseases See omnystudio.com/listener for privacy information.
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    49 mins
  • Wisom Wednesdays: The greatest public health crisis of our time - and what we need to do about it.
    Nov 19 2025

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    17 mins
  • Mojo Monday - The Pull To Belong With Carly Taylor
    Nov 16 2025

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    6 mins
  • Exploring Integrative Medicine and Holistic Health with Dr. Sandeep Gupta - Part Two
    Nov 14 2025
    Part Two of my engaging chat with Dr. Sandeep Gupta as we delve into the world of longevity, exploring a multitude of strategies designed to extend not just lifespan but healthspan as well. From the basics of supplements to advanced therapies, Dr. Gupta details a comprehensive approach to living not only longer but better. What You'll Learn: Understanding Supplements and Lifestyle: Discover the intrinsic role supplements play as secondary to beneficial lifestyle habits, emphasising that no supplement can substitute a poor lifestyle.Intermittent Fasting and Diet Tips: Learn the benefits of intermittent fasting and the importance of balancing protein and fasting to optimise the mTOR pathway without over activating it.Advanced Interventions: Explore hormone replacement therapy's role in improving quality of life during menopause and andropausal stages, and how these therapies are evolving.Pharmaceutical Opportunities: Gain insights into the judicious use of medications such as semaglutide and manjaro for weight management and metabolic health.Heavy Metals and Detoxification: Understand the impacts of heavy metals in the body, how they can disrupt enzyme functions, and effective ways to manage and detoxify them.Challenges in Longevity Health: Recognise common anti-longevity habits, such as excessive alcohol consumption, and how they can hinder your overall quality of life. Key Takeaways: Supplements Can't Replace Lifestyle: Emphasising good sleep, stress management, and regular exercise as the foundation of good health.Dietary Balance is Crucial: The right balance between protein intake and fasting periods can prevent chronic activation of growth pathways detrimental to longevity.Hormonal Health is Vital: Balanced hormone levels play a crucial role in longevity and quality of life, particularly as we age.Innovative Medications: Certain medications, carefully selected and used, can support weight management and metabolic health, crucial elements in longevity.Impact of Toxins: Regular detoxification and maintaining mineral balance effectively counteract heavy metal toxicity, enhancing longevity prospects.Live Mindfully: Reducing alcohol intake and focusing on holistic happiness can profoundly impact longevity and overall health. Resources To delve deeper into integrative health approaches and longevity practices, consider exploring resources and studies on metabolic syndrome, holistic care interventions, and the benefits of nature exposure. Engage with Dr. Sandeep Gupta About Sandeep: https://linktr.ee/drsandeepgupta Clinic: https://www.lotusholisticmedicine.com.au/dr-sandeep-gupta/ https://www.facebook.com/drsgupta/ https://www.linkedin.com/in/drsandeepgupta/ https://www.instagram.com/drsandeepgupta/?hl=en https://www.youtube.com/c/drsandeepgupta https://x.com/drsandeepgupta Support the Podcast If you found this conversation valuable, consider subscribing and leaving a review on your preferred podcast platform. Your feedback helps us continue to bring you insightful discussions on important health topics. Join the conversation on living a vibrant, balanced life, rich in health and vitality that allows you to enjoy more years of joyful living. Share this episode with someone who might benefit from these insights—because understanding integrative health can make all the difference. 00:00 Introduction to Supplements and Longevity 00:44 The Role of Lifestyle in Longevity 03:05 Intermittent Fasting and Its Benefits 03:59 Balancing Protein and mTOR Pathway 06:24 Practical Tips for Intermittent Fasting 11:02 Advanced Interventions: Hormone Therapy 16:11 Bioidentical Hormone Replacement Therapy 22:07 The Impact of Hormones on Mental Health 23:07 Exploring Pharmaceutical Interventions 23:45 Understanding Cardiovascular Health 28:05 Metabolic Health and Weight Loss Drugs 33:54 Mitochondrial Support and NAD 38:40 Heavy Metals and Detoxification 42:34 Biggest Anti-Longevity HabitSee omnystudio.com/listener for privacy information.
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    47 mins
  • Wisdom Wednesdays: How to train your immune system's 'sniper cells'
    Nov 12 2025

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    7 mins
  • Mojo Monday - Let Life Be Bigger Than You With Carly Taylor
    Nov 9 2025

    In this episode, Carly reflects on an idea that maybe we don’t need to explain or problem solve everything we feel. Drawing on Japanese Psychology and Morita Therapy, she explores what it means to accept our humanness rather than fight against it.

    Carly Taylor is a Mental Fitness Coach and Counsellor, helping people to strengthen their mental fitness and live with purpose. Her work is all about prevention, giving people the tools to manage their thoughts and emotions before they reach breaking point.

    To find out more about Carly, visit www.carlytaylorcoaching.com.au.
    Follow her on Instagram: carly_taylor_coaching

    See omnystudio.com/listener for privacy information.

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    5 mins
  • Exploring Integrative Medicine and Holistic Health with Dr. Sandeep Gupta - Part One
    Nov 7 2025

    In this insightful discussion, I chat with Dr. Sandeep Gupta, a proponent of integrative medicine and longevity health. We explore the evolving landscape of healthcare, discuss the limitations of the traditional medical system, and delve into the holistic approaches to health that focus on both healthspan and lifespan.

    What You'll Learn:

    1. The Shift to Integrative Medicine: Discover why Dr. Gupta transitioned from traditional pathways to focus on integrative and holistic approaches, driven by personal experiences and the need for a comprehensive view of health.
    2. Challenges in Traditional Medicine: Uncover the stigmas associated with holistic health approaches in the conventional medical setting and how these have historically been viewed by the medical community.
    3. Medicine 3.0 and Longevity: Understand Dr. Gupta's focus on healthspan and longevity, emphasising quality years of life filled with passion, joy, and meaning over merely extending lifespan.
    4. Metabolic Health and Chronic Diseases: Learn about the significance of metabolic health, its impact on major diseases, and how insulin resistance syndrome underpins many health issues.
    5. Diet and Longevity: Explore dietary recommendations for longevity, recognising the absence of a one-size-fits-all diet, and the importance of reducing sugar and refined carbohydrates.
    6. Muscle Mass and Health: Grasp the crucial role of maintaining muscle mass, its anti-inflammatory benefits, and its significance in preventing sarcopenia and indirectly reducing risks for major health disorders.

    Key Takeaways:

    • Integrative medicine can offer a more complete approach to health, focusing not only on treating diseases but promoting overall well-being and longer healthspans.
    • Traditional medicine often emphasises treatment of disease over prevention and maintenance of optimal health, a paradigm explored through Medicine 3.0.
    • Metabolic syndrome is a silent precursor to many chronic illnesses, and dietary choices play a crucial role in managing this risk.
    • Muscle health is vital; maintaining muscle mass as we age can prevent systemic issues and chronic disease.
    • A balanced diet rich in diverse, colourful foods can bolster metabolic health and support a robust microbiome.
    • Grounding and nature exposure are gaining recognition for their potential health benefits, including reducing inflammation and improving mental well-being.

    Resources

    To delve deeper into integrative health approaches and longevity practices, consider exploring resources and studies on metabolic syndrome, holistic care interventions, and the benefits of nature exposure.

    Engage with Dr. Sandeep Gupta

    About Sandeep: https://linktr.ee/drsandeepgupta

    Clinic: https://www.lotusholisticmedicine.com.au/dr-sandeep-gupta/

    https://www.facebook.com/drsgupta/

    https://www.linkedin.com/in/drsandeepgupta/

    https://www.instagram.com/drsandeepgupta/?hl=en

    https://www.youtube.com/c/drsandeepgupta

    https://x.com/drsandeepgupta

    Support the Podcast

    If you found this conversation valuable, consider subscribing and leaving a review on your preferred podcast platform. Your feedback helps us continue to bring you insightful discussions on important health topics.

    Share this episode with someone who might benefit from these insights—because understanding integrative health can make all the difference.

    00:18 Journey from Traditional to Integrative Medicine

    02:12 Challenges in Holistic Medicine

    07:01 Medicine 3.0: Healthspan vs. Lifespan

    08:44 Longevity Programs and Initial Assessments

    14:02 Metabolic Syndrome and Insulin Resistance

    21:23 The Challenge of Reversing Long-Term Health Issues

    21:28 Diet Recommendations for Longevity

    23:58 The Importance of Protein and Muscle Mass

    28:43 Inflammation and Longevity

    34:21 The Role of Microbiome in Health

    38:18 The Benefits of Nature and Grounding

    See omnystudio.com/listener for privacy information.

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    43 mins