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The Existential Hope Podcast

The Existential Hope Podcast

By: Foresight Institute
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The Existential Hope Podcast features in-depth conversations with people working on positive, high-tech futures. We explore how the future could be much better than today—if we steer it wisely.


Hosts Allison Duettmann and Beatrice Erkers from the Foresight Institute invite the scientists, founders, and philosophers shaping tomorrow’s breakthroughs— AI, nanotech, longevity biotech, neurotech, space, smarter governance, and more.


About Foresight Institute: For 40 years the independent nonprofit Foresight Institute has mapped how emerging technologies can serve humanity. Its Existential Hope program is the North Star: mapping the futures worth aiming for and the breakthroughs needed to reach them. This podcast is that exploration in public. Follow along and help tip the century toward success.


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  • Transcript, listed resources, and more: https://www.existentialhope.com/podcasts
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Foresight Institute
Science Social Sciences
Episodes
  • Andrew White on Building an AI Scientist to Automate Discovery
    Sep 10 2025

    What if we could build an AI that doesn't just answer questions, but makes fundamental scientific discoveries on its own? That's the mission of Future House, and in this episode, host Allison Duettmann sits down with its co-founder, Andrew White.


    Andrew shares the incredible journey that led him from chemical engineering to the forefront of the AI for Science revolution. He gives us a look under the hood at Future House's flock of specialized AI agents, like Crow, Finch, and Owl, and reveals how they recently accomplished in just three weeks what could have taken years: identifying an existing drug as a potential new treatment for a common cause of blindness.


    But the conversation doesn't stop at the successes. Andrew offers a sharp critique of the current methods for evaluating AI, explaining what’s wrong with benchmarks like "Humanity's Last Exam" and why the ultimate test is real-world discovery. He also makes a compelling case for completely reinventing the slow and inefficient scientific publishing system for an era where machines are both the producers and consumers of research.

    On the Existential Hope Podcast hosts Allison Duettmann and Beatrice Erkers from the Foresight Institute invite scientists, founders, and philosophers for in-depth conversations on positive, high-tech futures.


    Full transcript, listed resources, and more: https://www.existentialhope.com/podcasts


    Follow on X.

    Hosted on Acast. See acast.com/privacy for more information.

    Show More Show Less
    1 hr and 3 mins
  • Tools or Agents? Choosing Our AI Future | Anthony Aguirre
    Aug 22 2025

    What if the most desirable AI future is made of powerful tools, not autonomous agents? Physicist and futurist Anthony Aguirre joins us to unpack the Tool AI pathway, how incentives, liability, and design choices could steer us toward AI that empowers people rather than replaces them. We also situate this episode in AI Pathways, our two-scenario project exploring Tool AI and d/acc futures. Explore the project: https://ai-pathways.existentialhope.com/

    On the Existential Hope Podcast hosts Allison Duettmann and Beatrice Erkers from the Foresight Institute invite scientists, founders, and philosophers for in-depth conversations on positive, high-tech futures.


    Full transcript, listed resources, and more: https://www.existentialhope.com/podcasts


    Follow on X.

    Hosted on Acast. See acast.com/privacy for more information.

    Show More Show Less
    47 mins
  • Autonomous Vehicles Special: Andrew Miller on Self-Driving Futures
    Aug 12 2025

    Self-driving cars aren’t science fiction, they’re already here. But what kind of future are they steering us toward?


    In this episode, Beatrice speaks with Andrew Miller, mobility expert and author of The End of Driving, about the transformational promise, and very real risks, of autonomous vehicles. They explore why driverless tech isn’t just about hardware or software, but about regulation, land use, curb management, jobs, and values.


    From robo-taxis in San Francisco and driverless trucks in Texas, to curb chaos, job displacement, and how we reclaim space from parked cars, this episode goes far beyond the hype.

    On the Existential Hope Podcast hosts Allison Duettmann and Beatrice Erkers from the Foresight Institute invite scientists, founders, and philosophers for in-depth conversations on positive, high-tech futures.


    Full transcript, listed resources, and more: https://www.existentialhope.com/podcasts


    Follow on X.

    Hosted on Acast. See acast.com/privacy for more information.

    Show More Show Less
    35 mins
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