• Community EP049 - Early Delivery of a Drug Against Nogo-A with Dr. Norbert Weidner
    Aug 28 2025

    Join us this episode for a conversation with Norbert Weidner, MD, Professor and Chair of the Spinal Cord Injury Center at Heidelberg University Hospital. In this conversation we discuss results of a clinical trial called the Neuroimmunophilin Nogo-A Antibody in Spinal Cord Injury (NISCI) trial. Findings from this trial were published in a paper titled "Safety and efficacy of intrathecal antibodies to Nogo-A in patients with acute cervical spinal cord injury: a randomised, double-blind, multicentre, placebo-controlled, phase 2b trial" in the journal Lancet Neurology. In this paper Weidner and the NISCI team discuss the top-line findings from this large multi-center clinical trial where a drug (with antibodies against Nogo-A, a protein found in the walls of spinal cord neurons and their support cells) were given to people early after their accident. We invite you to listen in as Dr. Weidner gives an insider perspective on the NISCI trial, and trust you will enjoy our conversation on new pharmaology in the acute phase of SCI.

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    26 mins
  • Scholarly EP048 - the Neuroimmunophilin Nogo-A Antibody in Spinal Cord Injury (NISCI) trial with Dr. Norbert Weidner
    Aug 28 2025

    Join us this episode for a conversation with Norbert Weidner, MD, Professor and Chair of the Spinal Cord Injury Center at Heidelberg University Hospital. In this conversation we discuss results of the Neuroimmunophilin Nogo-A Antibody in Spinal Cord Injury (NISCI) trial, published in a paper titled "Safety and efficacy of intrathecal antibodies to Nogo-A in patients with acute cervical spinal cord injury: a randomised, double-blind, multicentre, placebo-controlled, phase 2b trial" in the journal Lancet Neurology. In this paper Weidner and their NISCI team discuss the top-line findings from a large multi-center clinical trial where antibodies against Nogo-A were administered to the spinal space early after acquired SCI. We invite you to listen in as Dr. Weidner gives an insider perspective on the NISCI trial, and trust you will enjoy our conversation on intrathecal drug delivery in the acute phase of SCI.

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    29 mins
  • Combined EP047 - Lived-Experience Neurotech Development with Jen French and Ian Burkhart
    May 30 2025

    Join us in this episode for a conversation with Jen French and Ian Burkhart, leaders of neurotech development movements and users of implanted neurological devices. Our guests share briefly about their experience with implanted devices, and then the conversation zooms in on exciting recently developments in implantable brain-computer interface (iBCI) and electrical simulation options such as epidural spinal cord stimulation (eSCS). Having been through the process, Jen and Ian deliberate on the importance and steps in engaging people with the lived-experience of paralysis in the development of meaningful clinical outcome assessments for clinical trials. Safety and aversion to electing for implantation are also discussed. We hope you enjoy this episode with Jen French and Ian Burkhart on these exciting neurological technologies and the role of lived-experience in neurotech now and in the future.

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    49 mins
  • Community EP046 - Argentinian Gait Rehabilitation with Dr. Terson de Paleville and Mr. Marcelo Gatti
    May 9 2025

    Join us this episode for a conversation with Daniela Terson de Paleville, PhD, professor of Physiology at the University of Louisville School of Medicine, and Marcelo Gatti, PT, director of neurorehabilitation in the area of spinal cord injury at Fleni Institute Escobar, Buenos Aires, Argentina. In this conversation we discuss the paper titled "Gait recovery in patients with late assessment of incomplete spinal cord injury: A retrospective study in Argentina" published in The Journal of Spinal Cord Medicine. In this paper Terson de Paleville and Gatti discuss the current state of neurorehabilitation targeting recovery of walking after incomplete spinal cord injury at the Fleni Institute in particular and Argentina more broadly. We invite you to listen in as Terson de Paleville and Gatti connect Latin America to ASIA both in their science and in our discussion, and trust you will enjoy our multi-lingual conversation on Argentinian gait rehabilitation.

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    23 mins
  • Scholarly EP045 - Argentinian Gait Rehabilitation with Dr. Terson de Paleville and Mr. Marcelo Gatti
    May 9 2025

    Join us this episode for a conversation with Daniela Terson de Paleville, PhD, professor of Physiology at the University of Louisville School of Medicine, and Marcelo Gatti, PT, director of neurorehabilitation in the area of spinal cord injury at Fleni Institute Escobar, Buenos Aires, Argentina. In this conversation we discuss the paper titled "Gait recovery in patients with late assessment of incomplete spinal cord injury: A retrospective study in Argentina" published in The Journal of Spinal Cord Medicine. In this paper Terson de Paleville and Gatti discuss the current state of neurorehabilitation targeting recovery of gait after incomplete spinal cord injury at the Fleni Institute in particular and Argentina more broadly. We invite you to listen in as Terson de Paleville and Gatti connect Latin America to ASIA both in their science and in our discussion, and trust you will enjoy our multi-lingual conversation on Argentinian gait rehabilitation.

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    22 mins
  • Combined EP044 - Unite 2 Fight Paralysis (U2FP) and their Cure Advocacy Network (CAN)
    Apr 8 2025

    Join us in this episode for a conversation with Matthew Rodreick, Executive Director of Unite 2 Fight Paralysis (U2FP). Matt offers a concise perspective on U2FP, including reflection on interaction between U2FP and ASIA. The thrust of the conversation then moves to the timely topic of state-level funding, with Matt running through success stories from U2FP's Cure Advocacy Network (CAN) and sharing his insider perspective on setting up state funding for spinal cord injury (SCI) research. We hope you enjoy this episode with Matt on the the past, present, and future of U2FP with a unique eye for a novel funding source.

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    36 mins
  • Community EP043 - Mapping Trunk Control and Rehabilitation with Dr. Bharad Nandakumar
    Feb 25 2025

    Join us this episode for a conversation with Bharadwaj "Bharad" Nandakumar, PhD, of The Miami Project to Cure Paralysis, for a conversation about the paper titled "Exercise therapy guides cortical reorganization after midthoracic spinal contusion to enhance control of lower thoracic muscles, supporting functional recovery" published in the journal Experimental Neurology. In this paper Dr. Nandakumar and his team leverage the proven power of somatotopic mapping to examine the less explored area of brain-trunk circuits and the effect that exercise has on recovery of neurological control of the trunk after spinal cord injury. We trust you will enjoy our conversation with Dr. Nandakumar on the important yet often overlooked topic of trunk control and rehabilitation.

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    24 mins
  • Scholarly EP042 - Mapping Trunk Control and Rehabilitation with Dr. Bharad Nandakumar
    Feb 25 2025

    Join us this episode for a conversation with Bharadwaj "Bharad" Nandakumar, PhD, of The Miami Project to Cure Paralysis, for a conversation about the paper titled "Exercise therapy guides cortical reorganization after midthoracic spinal contusion to enhance control of lower thoracic muscles, supporting functional recovery" published in the journal Experimental Neurology. In this paper Dr. Nandakumar and his team leverage the proven power of somatotopic mapping to examine the less explored area of brain-trunk circuits and the effect that exercise has on recovery of neurological control of the trunk after spinal cord injury. We trust you will enjoy our conversation with Dr. Nandakumar on the important yet often overlooked topic of trunk control and rehabilitation.

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    31 mins