Is 55% hematocrit dangerous? Why do people still think that androgen receptors downregulate?

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00:00:00 — INTRO 00:01:08 — Disclaimer (entertainment/education) 00:01:37 — Intro: Christmas Eve live Q&A + holiday check-in 00:02:30 — Post-surgery lifting update (cleared to train again) 00:03:24 — Surgery details (shoulder/labrum/rotator cuff/biceps tendon) 00:03:52 — Big Paul's Show timeline: decision later (after spring break/Disney) 00:04:14 — Current stats: bodyweight + height; open vs classic talk 00:05:04 — Current “baby cycle” / dosing routine 00:05:46 — GH schedule change (every day → every other day) 00:06:11 — Q&A begins 00:06:48 — Q: Add ~10 mg/day tren to 600 test / 300 primo? 00:08:16 — Q: TRT + clomiphene/enclomiphene; raising test without it 00:09:27 — Q: Masteron causes acne; possible causes / product quality 00:10:12 — Q: Lowering triglycerides on labs 00:13:25 — Q: Injectable glutathione (dose/route) + NAC use 00:14:47 — Q: Carb cycling at maintenance (what it looks like) 00:15:35 — Q: Cutting GH on high-carb days 00:16:35 — Q: Hematocrit at 55%—how concerned? 00:18:56 — Q: Cycle critique (test/EQ/MP/GH/orals + insulin sensitivity plan) 00:19:32 — Q: Bad coaching experiences/coach ignoring feedback 00:23:20 — Q: Fasting glucose 100–110 with GH (what’s going on?) 00:24:50 — Topic: GLP-1 access/patents / legality debate 00:31:11 — Q: 10–20 sets/week per muscle—rule of thumb vs individual 00:33:32 — Q: Post-show E2 recovery timing 00:37:20 — Q: Sourcing outside the US vs inside (risk comparison) 00:38:33 — Q: First cycle setup (test-only vs adding compounds) 00:39:02 — Q: MENT experience / recomp use 00:40:07 — Q: Older lifter on TRT—adding low-dose Deca for joints 00:42:52 — Topic: Peptide ban / “safety” argument; Tylenol comparison 00:44:42 — Q: Stopping TRT and returning to natural levels? 00:45:06 — Topic: Bodybuilding vs BJJ (conflicting goals) 00:47:34 — Topic: Androgen receptor “downregulation” 00:50:40 — Q: Tempo—slow negative vs squeeze (what matters?) 00:51:36 — Topic: Oral use timing (pre-workout vs offseason) 00:53:16 — Q: “Recomp” approach + minimum test for results 00:54:15 — Topic: SS-31 / “mitochondrial” peptides discussion 00:57:04 — Q: Bulk plan—test + Deca; adding injectable Dbol; add mast/EQ? 01:00:19 — Q: Attending the Arnold? 01:02:13 — Q: Cycle log template (where to get it) 01:02:19 — Q: PCT (tamoxifen + enclo/clomid) 01:03:41 — Q: Sustanon thoughts 01:05:01 — Q: Highest total dose ever run / longest run 01:05:36 — Q: Arimidex vs Aromasin preference 01:06:32 — Topic: Coaching natties vs PED users; diet focus 01:09:23 — Q: Labs to watch on test vs multi-compound cycles (HDL/LDL etc.) 01:16:40 — Wrap-up/goodbye

WARNING

========

The Video has been made available for entertainment and educational purposes only. I do not make any warranties to the accuracy, applicability, fitness, or completeness of the content.

The content is not intended to be a substitute for professional medical or legal advice, diagnosis, or treatment. Always seek the advice of your physician or qualified health provider. Never disregard professional medical advice or delay in seeking it because of something you have seen on this channel.

I hereby disclaim any and all liability to any party for any direct, indirect, implied, punitive, special, incidental, or other consequential damages arising directly or indirectly from any use of the content, which is provided as is, and without warranties.

We break down everything from testosterone potentially leaving the schedule list and an upcoming peptide crackdown to the latest Retatrutide trial results and major bodybuilding news like John Cena’s retirement and the Arnold Classic lineup. The crew dives into coaching philosophy, steroid ratios, Winstrol forms, mind–muscle connection, and health questions on Ashwagandha, Telmisartan, inflammation, and post-surgery peptides. Paul shares updates on his own training, gaining 30 pounds on cycle, and why he’s not taking criticism from people who don’t lift. Plus, thoughts on Shaun Clarida, Dorian Yates, Wesley Vissers, new Vegas gyms, cheat meals, gyno prevention, and more.

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0:01:12 - Thoughts On The Arlington Cemetery & The Tomb Of The Unknown Soldier 0:03:02 - Big Paul Has Gained 30 Pounds Since Starting His Cycle 0:04:28 - Testosterone Finally Might Be Taken Off The Schedule List 0:07:06 - There’s Going To Be A Huge Crackdown On Peptides 0:10:17 - Thoughts On Retatrutide Phase 3 Trial Results 0:13:52 - John Cena Retired From Wrestling - Paul’s Guilty Pleasures 0:16:00 - Barry Bonds Head & Shoe Size After Gear 0:18:29 - Thoughts On Guys Looking For Shaft Protocols 0:19:45 - Steve Just Doesn’t Give A F! 0:20:32 - Big Guy Redemption Story - De’Von Barnes Becoming An IFBB Pro 0:24:51 - Thoughts On Shaun Clarida 0:27:47 - There Are Clients You Have To Pull Back From Doing Too Much 0:29:12 - Will The Olympia Let Shaun Clarida Do The 212 & The Open? 0:32:40 - Thoughts On Dorian Yates 0:33:29 - Thoughts On Wesley Vissers Competing At The Arnold 0:34:45 - The Arnold Classic Competitors List 0:37:33 - Thoughts On Samson Not Competing + Arnold Classic Prize Money 0:39:51 - Thoughts On People Hating On Nick 0:42:20 - You Don’t Need Much Guidance In The Offseason 0:44:00 - Sometimes Even Coaches Need Coaches 0:45:03 - Coaching Advanced Guys Is More Flexible 0:48:32 - Paul’s Having Fun Training Again 0:50:12 - Winstrol Oil Vs. Winstrol Suspension 0:53:12 - Do You Titrated Test Dose Down After Ending A Cycle With EQ? 0:54:12 - Paul Fought Hard To Get Rid Of Southern Accent 0:55:23 - Research Only Peptide Sellers Will Die Off 0:56:26 - Thoughts On Training With The Neubie 1:01:41 - How To Get More Mind-Muscle Connection 1:02:58 - Interactions Between Ashwaghanda & Thyroid Meds 1:06:18 - Does Telmisartan Increase Risk Of Hyperkalemia? 1:09:07 - Time To Wait Post-Surgery Before Using BPC & TB-500 1:11:15 - Best Of The New Gyms In Las Vegas 1:15:50 - How To Reduce Systemic Inflammation 1:19:12 - When Is Jackie Starting Prep? 1:20:57 - Advice On Using English Toffee Stevia 1:21:51 - Thoughts On Cheat Meals 1:25:06 - Thoughts On Ratios Between Steroids + Thoughts On EQ 1:29:45 - In Person Vs. Online Coach 1:33:01 - Best Way To Prevent Gyno 1:37:17 - Paul Is NOT Accepting Criticism From People Who Don’t Lift 1:42:24 - Thoughts On Delusional People On Social Media 1:48:47 - Wrapping Up!

WARNING

========

The Video has been made available for entertainment and educational purposes only. I do not make any warranties to the accuracy, applicability, fitness, or completeness of the content.

The content is not intended to be a substitute for professional medical or legal advice, diagnosis, or treatment. Always seek the advice of your physician or qualified health provider. Never disregard professional medical advice or delay in seeking it because of something you have seen on this channel.

I hereby disclaim any and all liability to any party for any direct, indirect, implied, punitive, special, incidental, or other consequential damages arising directly or indirectly from any use of the content, which is provided as is, and without warranties.

Retatrutide is Eli Lilly’s investigational triple agonist (GLP-1 + GIP + glucagon) and the newest “next-gen” metabolic drug everyone in the GLP-1 world is watching. In this video, Big Paul breaks down the new Phase 3 TRIUMPH-4 topline results in adults with obesity + knee osteoarthritis (without diabetes)—including the absolutely wild weight-loss numbers, the arthritis pain improvement, and the side effects people keep reporting.

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WARNING

========

The Video has been made available for entertainment and educational purposes only. I do not make any warranties to the accuracy, applicability, fitness, or completeness of the content.

The content is not intended to be a substitute for professional medical or legal advice, diagnosis, or treatment. Always seek the advice of your physician or qualified health provider. Never disregard professional medical advice or delay in seeking it because of something you have seen on this channel.

I hereby disclaim any and all liability to any party for any direct, indirect, implied, punitive, special, incidental, or other consequential damages arising directly or indirectly from any use of the content, which is provided as is, and without warranties.

Big Paul is back with another anabolic Q&A – answering real questions from YouTube and the School of Anabolic Bodybuilding members community about training, diet, PEDs, and staying as safe as possible while you idiots try to get jacked.

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00:00 - Intro 01:37 - Can You Mix Esters In The Same Syringe? 05:40 - Reasons Why Carb Cycling Tends To Be The Best Diet 14:23 - How To Lower C-Reactive Protein 18:42 - Best Way To Bring Up Lagging Muscles 23:21 - Thoughts On Pairing 8 IU HGH To 800mg Total Androgens 27:19 - Does L-Carnitine Increase Androgen Receptor Density? 29:46 - What Is The Best Insulin Protocol? 36:43 - Thoughts On Fish Oil 40:35 - Best Practices To Reduce Cardiovascular Risk In Bodybuilding 46:39 - Importance Of Controlling Blood Pressure 49:22 - Should You Front-Load Long Esters? 52:59 - Wrapping Up!

WARNING!!

========

The Video has been made available for entertainment and educational purposes only. I do not make any warranties to the accuracy, applicability, fitness, or completeness of the content.

The content is not intended to be a substitute for professional medical or legal advice, diagnosis, or treatment. Always seek the advice of your physician or qualified health provider. Never disregard professional medical advice or delay in seeking it because of something you have seen on this channel.

I hereby disclaim any and all liability to any party for any direct, indirect, implied, punitive, special, incidental, or other consequential damages arising directly or indirectly from any use of the content, which is provided as is, and without warranties.

In today’s video, IFBB Pro and coach Big Paul reacts to an epic conversation between bodybuilding legends *Lee Priest* and Jay Cutler. Lee breaks down the cycles he used back in the 90s – his “low dose” test, Dbol, growth hormone, and limited Tren – and I give my honest thoughts as a modern pro who’s been around this game for decades.

Podcast Template

🔗 For All My Info & Resources, Visit Link Tree: https://linktr.ee/anabolicbodybuilding

WARNING

========

The Video has been made available for entertainment and educational purposes only. I do not make any warranties to the accuracy, applicability, fitness, or completeness of the content.

The content is not intended to be a substitute for professional medical or legal advice, diagnosis, or treatment. Always seek the advice of your physician or qualified health provider. Never disregard professional medical advice or delay in seeking it because of something you have seen on this channel.

I hereby disclaim any and all liability to any party for any direct, indirect, implied, punitive, special, incidental, or other consequential damages arising directly or indirectly from any use of the content, which is provided as is, and without warranties.

Live Q&A with IFBB Pro Big Paul. These questions and many more.

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0:00:00 - Intro 0:02:26 - Updates On Big Paul’s Training Post-Surgery 0:04:17 - Would Big Paul Want To Compete? 0:05:03 - Current Physique Update 0:06:43 - Thoughts On Clients Eating Chicken Thighs During Contest Prep 0:07:55 - What Can You Consider High ALT? 0:08:28 - Thoughts On MOTS-c & Reta 0:09:01 - EQ Can Crush E2 0:09:58 - Thoughts On People Trying To Take Down Mike Israetel 0:12:07 - Thoughts On Unilateral Training While Training 0:13:04 - Do You Need To Change Your Training Routine? + Thoughts On The Bro Split 0:14:05 - What Pro Show Would Paul Want To Do? 0:16:17 - How Hard Should You Cut Before A Rebound? 0:17:50 - What’s The Ideal LDL Level? 0:19:23 - How Long Should A Diet Break Be? 0:19:56 - When Do You Start Seeing Results From HGH? 0:20:26 - Do You Get High Prolactin From Nandrolone Or Tren? 0:22:17 - How To Deal With Clients With An Adaptable Metabolism 0:23:28 - When Should You Stop A Bulk? 0:24:13 - Big Paul Had A Lot Of Water Retention Recently 0:25:41 - How To Deal With Golfers' Elbow 0:26:50 - Can People Be Non-Responders To BP Meds? 0:29:23 - What Is The Ideal Fat Loss Per Week? 0:30:10 - Does Paul Like Using A Gi During Jujitsu? 0:32:38 - Thoughts On Test, NPP & HGH Cycle 0:33:47 - How Much Muscle Can You Hold On To If You Stop Using Gear? 0:36:51 - Thoughts On MOTS-c & SLU In The Offseason 0:38:21 - How Would Anadrol Affect Blood Work? 0:38:59 - How To Know Your Response To Androgens 0:39:49 - What’s The Upper Limit Of Reta For A Client? 0:40:13 - Differences Between MOTS-c & Reta 0:41:21 - Should You Inject Daily? + How Quickly Do You Go Back To Maintenance Cals? 0:42:23 - Who’s Going To Come Out With Real Follistatin? 0:43:01 - Favorite Supplement Brands 0:43:41 - Thoughts On Elevated BP From Test, EQ & NPP 0:44:13 - There Are Multiple Pathways For Muscle Growth 0:47:16 - Thoughts On Mitochondrial Peptides 0:48:20 - Will Paul Be At The Arnold? 0:49:01 - Story On Phil Heath Becoming A Pro On 300mg Deca 0:49:37 - Most People Never Make It Past The Intermediate Lifter Stage 0:51:11 - Can Overweight Guys Use HGH? 0:52:09 - Thoughts On GHK-Cu 0:54:47 - Thoughts On Combining NPP + Tren & Their Effects On Sleep 0:56:34 - Software Recommendations For Bodybuilding Apps 0:57:13 - Thoughts On HRV 0:57:51 - Thoughts On Steroids’ Effects On The Brain 0:59:45 - Thoughts On Myostatin Inhibitors 1:02:08 - Does Reta Actually Work Or Is It Overhyped? 1:04:56 - A Lot Of Other Peptides Are Being Overhyped 1:07:17 - Wrapping Up! Paul’s Blocking All The Weirdos! 1:09:04 - Will There Be Coaching Discounts For Christmas? 1:10:20 - Closing Thoughts

WARNING

========

The Video has been made available for entertainment and educational purposes only. I do not make any warranties to the accuracy, applicability, fitness, or completeness of the content.

The content is not intended to be a substitute for professional medical or legal advice, diagnosis, or treatment. Always seek the advice of your physician or qualified health provider. Never disregard professional medical advice or delay in seeking it because of something you have seen on this channel.

I hereby disclaim any and all liability to any party for any direct, indirect, implied, punitive, special, incidental, or other consequential damages arising directly or indirectly from any use of the content, which is provided as is, and without warranties.

Mortality in male bodybuilding just got hard numbers. In this video, I break down a new 16-year European Heart Journal study that tracked 20,286 IFBB bodybuilders (2005–2020) and recorded 121 deaths, with sudden cardiac death as the leading cause. We look at why pros are dramatically higher risk than amateurs, what’s really happening around contest prep, and how PED use ties into cardiovascular and kidney health.

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WARNING

========

The Video has been made available for entertainment and educational purposes only. I do not make any warranties to the accuracy, applicability, fitness, or completeness of the content.

The content is not intended to be a substitute for professional medical or legal advice, diagnosis, or treatment. Always seek the advice of your physician or qualified health provider. Never disregard professional medical advice or delay in seeking it because of something you have seen on this channel.

I hereby disclaim any and all liability to any party for any direct, indirect, implied, punitive, special, incidental, or other consequential damages arising directly or indirectly from any use of the content, which is provided as is, and without warranties.

IFBB Pro Big Paul answers your questions about training, nutrition, and safer performance enhancement.

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00:00 - Intro 01:24 - Make Sure To Like & Subscribe! 01:55 - How To Adjust Estrogen On A Test, Nandrolone & EQ Cycle 06:49 - When Is It Time To End A Mass Phase? 11:02 - Growth Hormone Vs. GH Secretagogues 14:34 - How To Adjust Training Volume In A PPL Split 17:50 - Thoughts On Insulin Use In The Offseason & Fat-Loss Phase 22:50 - How Do GLP-1s Impact Insulin Use? 25:12 - Thoughts On 65+ Year Olds Using HGH For More Muscle 31:10 - PED Cycle Outline For Powerlifting & Strongman? 37:24 - What’s The Secret For A Great Glute Spread?! 39:45 - Wrapping Up!

WARNING

========

The Video has been made available for entertainment and educational purposes only. I do not make any warranties to the accuracy, applicability, fitness, or completeness of the content.

The content is not intended to be a substitute for professional medical or legal advice, diagnosis, or treatment. Always seek the advice of your physician or qualified health provider. Never disregard professional medical advice or delay in seeking it because of something you have seen on this channel.

I hereby disclaim any and all liability to any party for any direct, indirect, implied, punitive, special, incidental, or other consequential damages arising directly or indirectly from any use of the content, which is provided as is, and without warranties.