Is 55% hematocrit dangerous? Why do people still think that androgen receptors downregulate?

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00:00:00 — INTRO 00:01:08 — Disclaimer (entertainment/education) 00:01:37 — Intro: Christmas Eve live Q&A + holiday check-in 00:02:30 — Post-surgery lifting update (cleared to train again) 00:03:24 — Surgery details (shoulder/labrum/rotator cuff/biceps tendon) 00:03:52 — Big Paul's Show timeline: decision later (after spring break/Disney) 00:04:14 — Current stats: bodyweight + height; open vs classic talk 00:05:04 — Current “baby cycle” / dosing routine 00:05:46 — GH schedule change (every day → every other day) 00:06:11 — Q&A begins 00:06:48 — Q: Add ~10 mg/day tren to 600 test / 300 primo? 00:08:16 — Q: TRT + clomiphene/enclomiphene; raising test without it 00:09:27 — Q: Masteron causes acne; possible causes / product quality 00:10:12 — Q: Lowering triglycerides on labs 00:13:25 — Q: Injectable glutathione (dose/route) + NAC use 00:14:47 — Q: Carb cycling at maintenance (what it looks like) 00:15:35 — Q: Cutting GH on high-carb days 00:16:35 — Q: Hematocrit at 55%—how concerned? 00:18:56 — Q: Cycle critique (test/EQ/MP/GH/orals + insulin sensitivity plan) 00:19:32 — Q: Bad coaching experiences/coach ignoring feedback 00:23:20 — Q: Fasting glucose 100–110 with GH (what’s going on?) 00:24:50 — Topic: GLP-1 access/patents / legality debate 00:31:11 — Q: 10–20 sets/week per muscle—rule of thumb vs individual 00:33:32 — Q: Post-show E2 recovery timing 00:37:20 — Q: Sourcing outside the US vs inside (risk comparison) 00:38:33 — Q: First cycle setup (test-only vs adding compounds) 00:39:02 — Q: MENT experience / recomp use 00:40:07 — Q: Older lifter on TRT—adding low-dose Deca for joints 00:42:52 — Topic: Peptide ban / “safety” argument; Tylenol comparison 00:44:42 — Q: Stopping TRT and returning to natural levels? 00:45:06 — Topic: Bodybuilding vs BJJ (conflicting goals) 00:47:34 — Topic: Androgen receptor “downregulation” 00:50:40 — Q: Tempo—slow negative vs squeeze (what matters?) 00:51:36 — Topic: Oral use timing (pre-workout vs offseason) 00:53:16 — Q: “Recomp” approach + minimum test for results 00:54:15 — Topic: SS-31 / “mitochondrial” peptides discussion 00:57:04 — Q: Bulk plan—test + Deca; adding injectable Dbol; add mast/EQ? 01:00:19 — Q: Attending the Arnold? 01:02:13 — Q: Cycle log template (where to get it) 01:02:19 — Q: PCT (tamoxifen + enclo/clomid) 01:03:41 — Q: Sustanon thoughts 01:05:01 — Q: Highest total dose ever run / longest run 01:05:36 — Q: Arimidex vs Aromasin preference 01:06:32 — Topic: Coaching natties vs PED users; diet focus 01:09:23 — Q: Labs to watch on test vs multi-compound cycles (HDL/LDL etc.) 01:16:40 — Wrap-up/goodbye

WARNING

========

The Video has been made available for entertainment and educational purposes only. I do not make any warranties to the accuracy, applicability, fitness, or completeness of the content.

The content is not intended to be a substitute for professional medical or legal advice, diagnosis, or treatment. Always seek the advice of your physician or qualified health provider. Never disregard professional medical advice or delay in seeking it because of something you have seen on this channel.

I hereby disclaim any and all liability to any party for any direct, indirect, implied, punitive, special, incidental, or other consequential damages arising directly or indirectly from any use of the content, which is provided as is, and without warranties.

We break down everything from testosterone potentially leaving the schedule list and an upcoming peptide crackdown to the latest Retatrutide trial results and major bodybuilding news like John Cena’s retirement and the Arnold Classic lineup. The crew dives into coaching philosophy, steroid ratios, Winstrol forms, mind–muscle connection, and health questions on Ashwagandha, Telmisartan, inflammation, and post-surgery peptides. Paul shares updates on his own training, gaining 30 pounds on cycle, and why he’s not taking criticism from people who don’t lift. Plus, thoughts on Shaun Clarida, Dorian Yates, Wesley Vissers, new Vegas gyms, cheat meals, gyno prevention, and more.

🔗 For All My Info & Resources, Visit Link Tree: https://linktr.ee/anabolicbodybuilding

0:01:12 - Thoughts On The Arlington Cemetery & The Tomb Of The Unknown Soldier 0:03:02 - Big Paul Has Gained 30 Pounds Since Starting His Cycle 0:04:28 - Testosterone Finally Might Be Taken Off The Schedule List 0:07:06 - There’s Going To Be A Huge Crackdown On Peptides 0:10:17 - Thoughts On Retatrutide Phase 3 Trial Results 0:13:52 - John Cena Retired From Wrestling - Paul’s Guilty Pleasures 0:16:00 - Barry Bonds Head & Shoe Size After Gear 0:18:29 - Thoughts On Guys Looking For Shaft Protocols 0:19:45 - Steve Just Doesn’t Give A F! 0:20:32 - Big Guy Redemption Story - De’Von Barnes Becoming An IFBB Pro 0:24:51 - Thoughts On Shaun Clarida 0:27:47 - There Are Clients You Have To Pull Back From Doing Too Much 0:29:12 - Will The Olympia Let Shaun Clarida Do The 212 & The Open? 0:32:40 - Thoughts On Dorian Yates 0:33:29 - Thoughts On Wesley Vissers Competing At The Arnold 0:34:45 - The Arnold Classic Competitors List 0:37:33 - Thoughts On Samson Not Competing + Arnold Classic Prize Money 0:39:51 - Thoughts On People Hating On Nick 0:42:20 - You Don’t Need Much Guidance In The Offseason 0:44:00 - Sometimes Even Coaches Need Coaches 0:45:03 - Coaching Advanced Guys Is More Flexible 0:48:32 - Paul’s Having Fun Training Again 0:50:12 - Winstrol Oil Vs. Winstrol Suspension 0:53:12 - Do You Titrated Test Dose Down After Ending A Cycle With EQ? 0:54:12 - Paul Fought Hard To Get Rid Of Southern Accent 0:55:23 - Research Only Peptide Sellers Will Die Off 0:56:26 - Thoughts On Training With The Neubie 1:01:41 - How To Get More Mind-Muscle Connection 1:02:58 - Interactions Between Ashwaghanda & Thyroid Meds 1:06:18 - Does Telmisartan Increase Risk Of Hyperkalemia? 1:09:07 - Time To Wait Post-Surgery Before Using BPC & TB-500 1:11:15 - Best Of The New Gyms In Las Vegas 1:15:50 - How To Reduce Systemic Inflammation 1:19:12 - When Is Jackie Starting Prep? 1:20:57 - Advice On Using English Toffee Stevia 1:21:51 - Thoughts On Cheat Meals 1:25:06 - Thoughts On Ratios Between Steroids + Thoughts On EQ 1:29:45 - In Person Vs. Online Coach 1:33:01 - Best Way To Prevent Gyno 1:37:17 - Paul Is NOT Accepting Criticism From People Who Don’t Lift 1:42:24 - Thoughts On Delusional People On Social Media 1:48:47 - Wrapping Up!

WARNING

========

The Video has been made available for entertainment and educational purposes only. I do not make any warranties to the accuracy, applicability, fitness, or completeness of the content.

The content is not intended to be a substitute for professional medical or legal advice, diagnosis, or treatment. Always seek the advice of your physician or qualified health provider. Never disregard professional medical advice or delay in seeking it because of something you have seen on this channel.

I hereby disclaim any and all liability to any party for any direct, indirect, implied, punitive, special, incidental, or other consequential damages arising directly or indirectly from any use of the content, which is provided as is, and without warranties.

Retatrutide is Eli Lilly’s investigational triple agonist (GLP-1 + GIP + glucagon) and the newest “next-gen” metabolic drug everyone in the GLP-1 world is watching. In this video, Big Paul breaks down the new Phase 3 TRIUMPH-4 topline results in adults with obesity + knee osteoarthritis (without diabetes)—including the absolutely wild weight-loss numbers, the arthritis pain improvement, and the side effects people keep reporting.

🔗 For All My Info & Resources, Visit Link Tree: https://linktr.ee/anabolicbodybuilding

WARNING

========

The Video has been made available for entertainment and educational purposes only. I do not make any warranties to the accuracy, applicability, fitness, or completeness of the content.

The content is not intended to be a substitute for professional medical or legal advice, diagnosis, or treatment. Always seek the advice of your physician or qualified health provider. Never disregard professional medical advice or delay in seeking it because of something you have seen on this channel.

I hereby disclaim any and all liability to any party for any direct, indirect, implied, punitive, special, incidental, or other consequential damages arising directly or indirectly from any use of the content, which is provided as is, and without warranties.