Showing titles in Evolution & Genetics

Columnist and publisher Michael Shermer, once an evangelical Christian and a creationist, argues that Intelligent Design proponents invoke a combination of ad science, political antipathy, and flawed theology in their new brand of creationism. He refutes their pseudoscientific arguments and then demonstrates why conservatives and people of faith can and should embrace evolution. Why Darwin Matters is an incisive examination of what is at stake in the debate over evolution.

Few people know much about stem cell research beyond the ethical questions raised by using embryos. But in the last decade, stem cell research has made huge advances toward eliminating some of our most intractable diseases. Now this sweeping and accessible book introduces us to this cutting-edge science, which will revolutionize medicine and change the way we think about and treat disease.

Evolution is one of the most important processes in life. It not only explains the detailed history of life on earth, but its scope also extends into many aspects of our own contemporary behavior - who we are and how we got to be here, our psychology, our cultures - and greatly impacts modern advancements in medicine and conservation biology. Perhaps its most important claim for science is its ability to provide an overarching framework that integrates the many life sciences into a single unified whole. Yet, evolution has been, and continues to be, regarded with suspicion by many.

With stories that entertain as much as they inform, renowned evolutionist David Sloan Wilson outlines the basic principles of evolution and shows how, when properly understood, they can illuminate the length and breadth of creation, from the origin of life to the nature of religion.

With all the advances in science in the last century, why are there still so many infectious diseases? Why haven’t we found cures for difficult cancers? Why hasn’t any major progress been made in the treatment of mental illness? And how do we intend to stop, and not only that but reverse, global warming and the climate crisis? In Saved by Science, scientist Mark Poznansky examines the many crises facing humanity while encouraging us with the promise of an emerging solution: synthetic biology.

‘What is it like to be a bat?’, the philosopher Thomas Nagel famously asked concerning consciousness. For biologist Martin Stevens, the question forms the starting point of an exploration of animal senses. In this enthralling account, we learn not only of the wonder of animal senses, but how they work and how scientists go about investigating them. And, throughout, we consider how these senses came to be.

Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way.

p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.

In the early 1800s, a century before there was any concept of the gene, physicians in insane asylums began to record causes of madness in their admission books. Almost from the beginning, they pointed to heredity as the most important of these causes. As doctors and state officials steadily lost faith in the capacity of asylum care to stem the terrible increase of insanity, they began emphasizing the need to curb the reproduction of the insane. They became obsessed with identifying weak or tainted families and anticipating the outcomes of their marriages.

El ingenio de Millás y la sabiduría de Arsuaga unidos para contar la vida como la mejor de las historias.

For all that science knows about the living world, notes David P. Barash, there are even more things we don't know, genuine evolutionary mysteries that perplex the best minds in biology. Paradoxically, many of these mysteries are very close to home, involving some of the most personal aspects of being human. Homo Mysterious examines a number of these evolutionary mysteries, exploring things we don't yet know about ourselves, laying out the best current hypotheses, and pointing toward insights that scientists are just beginning to glimpse.

Are humans unwitting partners in evolution with psychedelic plants? Darwin’s Pharmacy shows they are by weaving the evolutionary theory of sexual selection and the study of rhetoric together with the science and literature of psychedelic drugs. Long suppressed as components of the human tool kit, psychedelic plants can be usefully modeled as “eloquence adjuncts” that intensify a crucial component of sexual selection in humans: discourse.

Die CRISPR-Methode und die Zukunft der Medizin. Was macht die Natur, wenn ein neuer Feind auftaucht? Sie findet eine neue Strategie. Wenn eine Bakterie von einem Virus attackiert wird, verteidigt sie sich beispielsweise, indem sie ihre genetische Struktur ändert. Doch wie können diese Mechanismen nachgewiesen werden? Und welchen Nutzen hat dieses Wissen für die Medizin? Der Amerikanerin Jennifer Doudna und der Französin Emmanuelle Charpentier sind bahnbrechende Erkenntnisse im Bereich der Biochemie gelungen.

Was ist Leben? Und was bedeutet die Antwort auf diese Frage für die Herausforderungen, denen sich die Menschheit heute gegenübersieht - Klimawandel, Pandemien und Artensterben? Paul Nurse erhielt den Nobelpreis dafür, gezeigt zu haben, wie lebende Zellen funktionieren. In seinem so klar wie elegant verfassten Buch synthetisiert er auf wenigen Seiten sämtliches Wissen darüber, was es heißt, am Leben zu sein. Schritt für Schritt erläutert Nurse die fünf revolutionären Ideen, die der Biologie zugrunde liegen - die Zelle, das Gen, Evolution durch natürliche Selektion, das Leben als Chemie und das Leben als Information.

As biologist Jeremy Griffith explains in THE Interview (which psychiatrist Professor Harry Prosen described as “the most important interview of all time”), while we humans lacked the explanation for our two-million-year corrupted human condition, we had no choice but to deny that our distant ape ancestors lived in a state of cooperative and loving innocence. But with the good reason for our corrupted condition now finally found, our species’ original state of innocence can at last be admitted.

Sociogenomics brings together advances in molecular genetics and traditional social and behavioral science. The key tool is the polygenic index, which allows us to analyze DNA to measure a child's genetic potential. Today, we can estimate a child's adult height, how far they will go in school, and their weight as an adult—all from a cheek swab, finger prick, or vial of saliva. Dalton Conley and other researchers are using this new science to shed light on the ways in which genes shape our world, influencing how each person both creates and responds to the environment around them.

From the cup of coffee that jump-starts the day to dangerously addictive drugs, the recreational use of plants with psychoactive properties has a long history among humans. But, as with many things, it turns out that other animals got there first. From parrots to primates, consuming medicinal chemicals is an instinctive behavior that helps countless organisms fight infection and treat disease. But the similarities don't end there: Like us, many creatures also consume substances that have no apparent benefit...except for inducing intoxication.

Without our domesticated plants and animals, human civilization as we know it would not exist. We would still be living at subsistence level as hunter-gatherers if not for domestication. It is no accident that the cradle of civilization - the Middle East - is where sheep, goats, pigs, cattle, and cats commenced their fatefully intimate associations with humans.

Just 45 years ago, the age of gene modification was born. Researchers could create glow-in-the-dark mice, farmyard animals producing drugs in their milk, and vitamin-enhanced rice that could prevent half a million people going blind every year. But now GM is rapidly being supplanted by a new system called CRISPR or "gene editing". Using this approach, scientists can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago.

At a conference in Hong Kong in November 2018, Dr. He Jiankui announced that he had created the first genetically modified babies - twin girls named Lulu and Nana - sending shockwaves around the world. A year later, a Chinese court sentenced Dr. He to three years in prison for "illegal medical practice". As scientists elsewhere start to catch up with China's vast genetic research program, gene editing is fueling an innovation economy that threatens to widen racial and economic inequality. Fundamental questions about science, health, and social justice are at stake.