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The Glucose Never Lies®

The Glucose Never Lies®

By: John Pemberton
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About this listen

Welcome to The Glucose Never Lies® Podcast where science meets real-life experience to empower diabetes management.


I’m John Pemberton. I’ve lived with type 1 diabetes since 2008 and have spent nearly 20 years mastering both the science and art of managing it. Through personal experimentation, published research, and my work as a diabetes specialist dietitian, I’ve gained deep insights into what truly makes a difference.


When my son Jude tested positive for type 1 antibodies, I realised that all the knowledge in my head is wasted if I couldn’t communicate it in a way that was clear, actionable, and easy to come back to. So I built The Glucose Never Lies® Education Programme—a free resource designed to teach diabetes management exactly as I’d want people to understand it if they were looking after my son.


After battling a functional motor disorder for many years and recently experiencing a major depressive episode, I was eventually pulled out of that hole by friends, family, and professionals who helped me get back to being me. That experience taught me the power of giving—and this podcast is my way of giving back.


My cohost, Louise Collins, is a highly experienced diabetes nurse with over 20 years in the field. She brings a wealth of knowledge and her superpower is making complex diabetes science accessible and practical for everyday life. She is the best diabetes nurse I have ever worked with, and there have been some good ones! Most importantly, she keeps me in check and on point!


So, if you’re living with diabetes or supporting someone who is, we want to make things easier, clearer, and—importantly—more enjoyable.


We hope you enjoy the content. If you do, please share it with those who may like it too.


Disclaimer: The information shared on The Glucose Never Lies® Podcast is for informational and educational purposes only. While we discuss strategies and insights for diabetes management, this podcast is not a substitute for professional medical advice. Always consult your healthcare team before making any changes to your diabetes care plan.

© 2025 The Glucose Never Lies®
Hygiene & Healthy Living
Episodes
  • Episode 12: CGM Functionality (Part 3): The Bells and Whistles
    May 9 2025

    In this episode of the Glucose Never Lies podcast, hosts John Pemberton and Louise discuss the intricacies of diabetes management, focusing on continuous glucose monitoring (CGM) systems. They explore various CGM features, including calibration, alarms, and connectivity with automated insulin delivery (AID) systems. The conversation emphasizes the importance of understanding individual needs when selecting a CGM, as well as the role of technology in enhancing diabetes care. The hosts also provide insights into the latest advancements in CGM technology and offer resources for further education.

    Takeaways

    • Continuous glucose monitors (CGMs) have evolved to include factory calibration.
    • Optional calibration can be beneficial but requires accurate blood glucose meters.
    • Alarm fatigue can hinder effective diabetes management.
    • The Freestyle Libre is noted for its small size and long wear time.
    • Dexcom products offer extensive connectivity with AID systems.
    • Understanding individual needs is crucial when selecting a CGM.
    • AI-driven forecasts in CGMs can enhance decision-making for users.
    • Education and support are vital for effective diabetes management.
    • Resources like the DSM Forum provide valuable information for diabetes care.

    Chapters

    00:00
    Introduction to Diabetes Management

    02:14
    Continuous Glucose Monitoring (CGM) Overview

    13:09
    Understanding CGM Features and Alarms

    21:27
    Evaluating CGM Size and Connectivity

    27:21
    Final Thoughts and Resources

    Key Resources:

    CGM Series: CGM: The Bells and Whistles

    Chart for CGM Devices (From May 2025): DSN Forum

    Tim Street @ Diabettech

    Show More Show Less
    30 mins
  • Episode 11: CGM Accuracy (Part 2): Understanding MARD, 20/20, 40/40, and Error Grids.
    Apr 10 2025

    In this episode of the Glucose Never Lies podcast, hosts John Pemberton and Louise discuss the intricacies of diabetes management, focusing on continuous glucose monitoring (CGM) systems. They explore the importance of CGM accuracy, the standards set by regulatory bodies, and the significance of testing conditions in evaluating these devices. The conversation delves into various metrics used to assess CGM performance, including MARD, 20/20 and 40/40 agreement rates, and highlights the need for robust testing against capillary glucose to ensure effective diabetes management. The episode emphasises the importance of transparency in CGM studies and the future directions for standardizing testing protocols.

    takeaways

    • CGM systems are crucial for real-time glucose monitoring.
    • FDA standards are currently the highest for CGM performance.
    • CE marking does not guarantee device accuracy or reliability.
    • Testing conditions significantly impact CGM accuracy results.
    • The 20/20 standard indicates no risk for insulin dosing decisions.
    • The 40/40 metric identifies high-risk readings in CGM data.
    • Robust testing against capillary glucose is essential for accuracy.
    • Standardization in CGM testing is needed for better diabetes management.
    • Transparency in CGM studies is vital for healthcare professionals and patients.

    00:00
    Introduction to Diabetes Management and Podcast Goals

    02:07
    Understanding Continuous Glucose Monitoring (CGM) Systems

    06:08
    Evaluating CGM Accuracy and Performance Standards

    10:09
    The Importance of Testing Conditions in CGM Studies

    14:13
    Metrics for Assessing CGM Accuracy

    18:03
    Comparing CGM Systems Against Capillary Glucose

    22:02
    Future Directions for CGM Testing and Standards

    Key Resources

    CGM Series: Assessing CGM Accuracy Performance

    Chart for CGM Devices (From May 2025): DSN Forum

    Tim Street @ Diabettech

    Show More Show Less
    32 mins
  • Episode 10: CGM Accuracy (Part 1) "Study Design First, Performance After"
    Apr 10 2025

    In this episode of the Glucose Never Lies podcast, hosts John Pemberton and Louise delve into the intricacies of diabetes management, focusing on continuous glucose monitoring (CGM) systems. They discuss the importance of understanding CGM accuracy, the significance of study design in evaluating sensor performance, and the key questions to ask when assessing the reliability of these devices. The conversation emphasises the need for robust testing conditions to ensure that CGMs provide accurate readings for insulin dosing decisions. The hosts also highlight the ongoing efforts towards standardisation in CGM technology to improve diabetes care.

    Takeaways

    • Continuous glucose monitors (CGMs) are crucial for insulin dosing decisions.
    • Understanding study design is essential for evaluating CGM accuracy.
    • Not all CGMs are created equal; performance varies significantly.
    • Key questions to assess CGM accuracy include the study population and testing conditions.
    • Robust testing conditions are necessary for reliable sensor performance.
    • The importance of peer-reviewed data in evaluating CGM accuracy.
    • Standardization in CGM technology is on the horizon.
    • Healthcare professionals should be knowledgeable about CGM performance.
    • A downloadable chart will be available to help users assess CGM options.

    Chapters

    00:00
    Introduction to Diabetes Management

    02:14
    Understanding Continuous Glucose Monitoring (CGM)

    05:11
    Accuracy of Continuous Glucose Monitors

    10:13
    Evaluating Sensor Performance

    15:45
    Key Questions for Sensor Accuracy

    20:31
    Moving Towards Standardization in CGM

    25:03
    Summary and Next Steps


    Key Resources

    CGM Series: Understanding Risk Before Performance

    Chart for CGM Devices (From May 2025): DSN Forum

    Tim Street @ Diabettech


    Show More Show Less
    28 mins

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