In this podcast episode, hosts Dr. Gene Bruno and Dr. Bill Clark reflect on the past year, discussing significant growth in their audience and the evolving trends in the nutraceutical industry. They highlight the increasing focus on women's health, longevity, and the demand for educated consumers seekingscientific evidence. The conversation also touches on the impact of AI in the industry, the popularity of GLP-1 drugs, and the innovations from NutriSelect. The hosts express gratitude for their listeners and share insights on the future of bioactive science and the importance of education in health and wellness.

In this episode, Dr. Bill Clark and Dr. Gene Bruno discuss their experiences at the Supply Side Global 2025 event, highlighting key trends in women's health and longevity. They delve into the significance of NutriSelect.ai, the importance of education sessions, and the dynamics between ingredient companies and product brands. The conversation also touches on recent studies regarding melatonin and its implications, as well as the transformative role of AI in thesupplement industry. The episode concludes with reflections on the event and predictions for the future.Keywords

Supply Side Global, Women's Health, Longevity, NutriSelect.ai, Education Sessions, Ingredient Companies, Melatonin, Consumer Trends, Health Tech, Biohacking

Takeaways

Women's health and longevity are emerging as significant trends in the nutraceutical industry.

NutriSelect.ai had a milestone year with over 35 meetings at Supply Side Global.

Education sessions focused on science attract larger audiences and enhance credibility.

Ingredient companies are eager to differentiate their products through research and branding.

The consumer market is increasingly interested in science-based products.

Melatonin's association with heart failure requires careful interpretation of studies.

AI technology is set to revolutionize the supplement industry and consumer purchasing behavior.

The importance of trust and transparency in product claims is paramount.

Networking at events like Supply Side Global fosters valuable connections and collaborations.

Future trends will likely focus on biohacking and personalized health solutions.

Chapters

00:00 Introduction and Overview of Supply Side Global

02:59 Key Trends: Women's Health and Longevity

05:53 NutriSelect.ai: A Milestone Year

08:55 Education Sessions and GLP-1 Agonists

11:55 Biohacking Longevity: Evidence-Based Nutraceuticals

14:54 Ingredient Companies and Product Brands

17:56 NutriSelect.ai: Consumer-Facing App and Future Vision

21:28 Exciting Developments in NutriSelect

24:40 Trends in Women's Health and Longevity

28:08 Understanding Melatonin and Heart Health

32:18 Trust and Transparency in Nutraceuticals40:56 Key Takeaways from Supply Side 2025

In this conversation, experts discuss the integration of AI in health technology, focusing on building trust among consumers, understanding the differences between generative and predictive AI, and the future of personalized nutrition. They emphasize the importance of evidence-based nutraceuticals and the need for transparency to enhance consumer confidence in AI applications. In this conversation, experts discuss the transformative role of AI in health andnutrition, emphasizing the importance of transparency, trust, and data integrity. They explore consumer perspectives on AI-driven supplement recommendations, the challenges of algorithmic bias, and the future potential of AI in personalizing health care. The discussion highlights the need for clear communication of scientific data to consumers and the evolving landscape of health technology.

Keywords

AI, health technology, personalized nutrition, trust in AI, predictive algorithms, consumer sentiment, nutraceuticals, evidence-based science, machine learning, biohacking, AI, health, nutrition, supplements, trust, transparency, algorithmic bias, consumer perspectives, future of health, NutriSelect

Takeaways

· AI is becoming integral in health technology.

· Public perception of AI is often rooted in mistrust.

· Generative AI is different from predictive AI.

· Trust in AI can be built through transparency and evidence.

· Personalized nutrition is the future of health supplements.

· AI can analyze vast amounts of data quickly and efficiently.

· Consumer sentiment is crucial for AI product acceptance.

· Evidence-based nutraceuticals are essential for credibility.

· AI can help in pattern recognition and optimization.

· The future of AI in health is about collaboration with experts.

· AI can help improve health marketing by providing real tools for consumers.

· Transparency in AI is essential for building consumer trust.

· Consumers need objective information about supplements, not just influencer hype.

· AI can analyze individual health data to provide personalized recommendations.

· The future of health care will involve more predictive medicine through AI.

· Algorithmic bias can lead to inaccurate AI outputs if data is not balanced.

· Consumers should be educated on the science behind health products in an understandable way.

· Wearable technology will play a significant role in health monitoring.

· AI can help bridge the gap between consumers and health professionals.

· The integration of AI in health will lead to more efficient and effective care.

Chapters

00:00 Introduction and Overview of AI in Health

02:57 Panelist Introductions and Backgrounds

06:02 Trust Issues and Public Perception of AI

09:14 Consumer Perspectives on AI in Health

12:01 AI 101: Understanding AI and Its Applications

14:50 Distinguishing Between Predictive and Generative AI

18:10 The Future of AI in Health and Nutrition

20:56 Challenges and Opportunities in AI Implementation

24:01 The Importance of Validation in Health Products

26:59 Conclusion and Future Directions

32:12 Building Trust in Science

35:04 The Role of AI in Personalized Nutrition

39:10 The Evolution of AI in Health Research

46:05 Trust, Transparency, and Ethics in AI

58:02 Understanding Science for the Everyday Consumer

58:37 Bridging the Gap: Science and Consumer Understanding

01:00:24 The Role of AI in Personal Health

01:02:47 Complexity of Natural Products and Personalization

01:06:01 The Future of AI in Health and Nutrition

01:11:47 Transforming Healthcare with Technology

01:18:10 Key Takeaways and Future Perspectives

In this episode of the Bioactive Nexus podcast, Dr. Bill Clark and Dr. Gene Bruno discuss Gene's recent trip to China for the Timepie Longevity Summit, exploring key insights on health,wellness, and the role of inflammation. They delve into traditional Chinese medicine, the cultural differences in dietary practices, and the future of NutriSelect's data-driven wellness platform. The conversation highlights the importance of bridging Eastern and Western health practices and the potential for collaboration in the nutraceutical industry.

Keywords

bioactive, longevity, inflammation, nutraceuticals, traditional Chinese medicine, health tech, NutriSelect, wellness, biohacking, dietary supplements

Takeaways

- Gene's trip to China included a fascinating experience at the Longevity Summit.

- The summit highlighted the importance of inflammation in health and longevity.

- Traditional Chinese medicine offers valuable insights into health practices.

- Dietary choices play a crucial role in managinginflammation.

- The use of nutraceuticals can help reduce chronic inflammation.

- AI and biohacking are more prevalent in China than in the U.S.

- NutriSelect aims to bridge the gap between consumers and ingredient suppliers.

- Cultural differences in food impact health and wellness practices.

- The supplement market in China is rapidly growing and innovative.

- Collaboration between East and West can enhance health and wellness solutions.

Chapters

00:00 Technical Difficulties and Podcast Introduction

02:10 Gene's Trip to China and the Longevity Summit

05:03 Key Insights on Inflammation and Health

07:57 Exploring Traditional Chinese Medicine

11:00 Cultural Differences in Food and Health Practices

16:19 The Future of NutriSelect and Data-Driven Wellness30:11 East Meets West: Bridging Knowledge in Health

In this episode, Dr. Bill Clark and Dr. Gene Bruno delve into the complexities of inflammation, particularly its role in aging and chronic diseases. They discuss the differences between acute and chronic inflammation, the molecular players involved, and how chronic inflammation accelerates age-related decline. The conversation also highlights the importance of nutraceuticals in managing inflammation and the best practices for formulating effective supplements. The episode emphasizes a proactive approach to health and the significance of evidence-based practices in the nutraceutical industry.

Keywords

inflammation, aging, nutraceuticals, chronic inflammation,health span, supplements, anti-inflammatory, wellness, longevity, immune system

Takeaways

- Inflammation can be both beneficial and harmfuldepending on its type.

- Acute inflammation is necessary for healing,while chronic inflammation is detrimental.

- NFKB is a key regulator in the inflammatoryprocess.

- Oxidative stress and inflammation areinterconnected in a vicious cycle.

- Chronic inflammation is linked to variousage-related diseases.

- Nutraceuticals can help manage inflammationeffectively.

- Using clinically relevant doses in formulationsis crucial.

- Avoid the kitchen sink approach in supplementformulation.

- Proactive health measures can mitigate theeffects of aging.

- Evidence-based practices are essential foreffective nutraceuticals.

Chapters

00:00 Introduction to Inflammation and Aging

07:21 Understanding Acute vs. Chronic Inflammation

14:10 Molecular Players in Inflammation

19:49 Impact of Chronic Inflammation on Aging

20:42 Understanding Chronic Inflammation

21:06 Exploring Anti-Inflammatory Botanicals

22:15 Nutrients and Lipids in Inflammation Management

24:35 The Role of Probiotics in Inflammation

26:25 Innovative Compounds for Inflammation Relief

28:13 The Power of Quercetin

30:00 Best Practices for Formulating Anti-Inflammatory Products

35:07 Proactive Approaches to Health and Inflammation

38:56 Looking Ahead: Future Innovations in Nutraceuticals

In this conversation, Dr. Bill Clark and Dr. Gene Brunoexplore the evolving landscape of personalized nutrition, discussing its definition, the spectrum of personalization, and the implications of emerging technologies. They emphasize the importance of scientific rigor and consumer trust in the industry, while also addressing the potential of biohacking and true precision nutrition. The discussion highlights the need for innovation and evidence-based approaches to meet the growing demand for personalized wellness solutions.

Keywords

personalized nutrition, precision nutrition, biohacking,nutraceuticals, health optimization, genomics, biomarkers, wellness, dietary supplements, health technology

Takeaways

· Personalized nutrition is about unique dietaryneeds for optimal health.

· The spectrum of personalized nutrition rangesfrom generalized to true precision.

· Most current personalized nutrition offeringsare not scientifically rigorous.

· Wearable technology is enhancing thepersonalization of nutrition.

· Biomarker-driven approaches are becoming moreaccessible and sophisticated.

· Biohacking allows individuals to take control oftheir health but lacks regulation.

· True precision nutrition combines various datainputs for tailored solutions.

· Consumer demand is shifting towardsevidence-based personalized wellness.

· The supplement industry must evolve to meetconsumer expectations for personalization.

· Innovation and consumer trust are key to thefuture of personalized nutrition.

Chapters

00:00 Introduction to Personalized Nutrition

02:55 Defining Personalized Nutrition

06:07 The Spectrum of Personalized Nutrition

08:53 Generalized Programs vs. Category-Based Personalization

11:57 Lifestyle and Symptom-Based Personalization

14:53 Biomarker Driven Personalization

17:45 Biohacking and DIY Personalization

18:52 Understanding Nutrigenomics and Biohacking

21:13 The Future of Precision Nutrition

26:13 Market Implications of Personalized Nutrition

33:32 The Evolution of Evidence-BasedSupplementation

In this special episode of The Bioactive Nexus, Dr. Gene Bruno interviews Dr. Bill Clark about the evolving state of the supplement industry and the launch of NutriSelect.ai, an innovative platform designed to enhance consumer trust and transparency.

Dr. Clark shares how NutriSelect.ai is addressing industry challenges with evidence-based supplementation and personalized health technology, while also unveiling the Brand Science Accelerator — a groundbreaking program created to help supplement companies strengthen theirbrand, science, and consumer connection.

This exclusive accelerator is now accepting applications,with only 5 brands invited to join the first cohort. Early movers will gain access to cutting-edge tools, strategy, and scientific insights to position their brand for growth in an increasingly competitive and regulated marketplace.

If you’re ready to elevate your brand and lead the future ofsupplementation, this is the moment to step forward.

👉 To learn more contact Dr. Bill Clark directly on LinkedIn or email at drbill@nutriselect.ai

Keywords

supplement industry, NutriSelect, consumer trust, AItechnology, Brand Science Accelerator, evidence-based supplementation, regulatory challenges, product evaluation, early movers, industry transformation

Takeaways

· The supplement industry is facing declining consumer trust.

· NutriSelect aims to empower consumers by providing transparency.

· There is a lack of standardized product evaluation in the industry.

· Brands making unsupported claims will face increased scrutiny.

· The NutriSelect app will provide objective ratings based on science.

· Early movers in the industry will benefit from adapting to new standards.

· The Brand Science Accelerator program helps brands improve their product efficacy.

· Brands must invest in clinical research to remain competitive.

· The industry is shifting towards evidence-based supplementation.

· Consumer demand for transparency will drive industry change.

Chapters

00:00 Introduction to the Supplement ShakeOut

02:26 Current Issues in the Supplement Industry

07:20 The Role of NutriSelect in the Industry

09:26 Opportunities for Early Movers

10:55 The Brand Science Accelerator Program

15:00 The Future of Supplement Brands

19:41 Next Steps for Interested Brands

In this episode of The Bioactive Nexus podcast, Dr. Bill Clark and Dr. Gene Bruno delve into the critical topic of cognitive function, particularly as it relates to aging and the growingmarket for brain health supplements. They discuss the importance of understanding cognitive function's subdomains, such as memory and attention, and explore the mechanisms of action that underpin various nutraceuticals. The conversation highlights market trends, key ingredients for cognitive support, and the significance of formulation strategies that consider consumer expectations. The episode concludes with insights into future topics, including the role of psychedelics in cognitive health and the importance of gut health for brain function.

Keywords

cognitive function, brain health, nutraceuticals, neuroplasticity, aging, supplements, mechanisms of action, market trends, formulation strategies, consumer expectations

Takeaways

· Cognitive function is crucial as we age.

· Neuroplasticity allows the brain to reorganizeitself.

· The nootropics market is rapidly growing.

· Different mechanisms of action should be used informulations.

· Realistic consumer expectations are essentialfor product success.

· Gut health significantly impacts cognitivefunction.

· Psychedelics are gaining attention in cognitivehealth research.

· Formulation strategies should avoid the kitchensink approach.

· Clinically relevant doses are necessary foreffectiveness.

· Brain health requires a long-term commitment.

Chapters

00:00 Introduction to Cognitive Function and Aging

07:16 Understanding Cognitive Function and Neuroplasticity

12:04 Market Trends in Brain Health Supplements

18:17 Mechanisms of Action in Cognitive Health

20:06 Key Ingredients for Cognitive Enhancement

21:46 Exploring Cognitive Enhancers: Lion's Mane and Ginkgo Biloba

23:21 The Power of Caffeine and Theanine

25:04 Omega-3s and Spermidine: Essential Nutrients for BrainHealth

26:53 Emerging Ingredients: Uridine Monophosphate and PQQ

28:49 The Role of Sage and Nicotinamide Riboside inCognitive Function

30:46 Neuroprotective Polyphenols: Blueberries and Curcumin

32:07 Formulation Strategies: Synergy and Dosing

35:23 Navigating Nootropic Claims: Real vs. Hype

38:56 Building Brand Loyalty Through Realistic Expectations

41:14 Final Takeaways: The Long Game of BrainHealth