My Favorite Learners Podcast: Local Anesthetic Onset, Duration, Toxicity & Clinical Pearls for SRNAs cover art

My Favorite Learners Podcast: Local Anesthetic Onset, Duration, Toxicity & Clinical Pearls for SRNAs

My Favorite Learners Podcast: Local Anesthetic Onset, Duration, Toxicity & Clinical Pearls for SRNAs

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In this solo episode of My Favorite Learners, host Chloe Gomez, DNP, CRNA, breaks down local anesthetics in a way that’s clear, memorable, and clinically relevant—whether you’re prepping for boards, placing your first spinal, or managing labor epidurals. Based on Chapter 10 of Nurse Anesthesia by Elisha et al. (2023), Chloe covers:

  • Mechanism of Action: How local anesthetics block voltage-gated sodium channels

  • Onset, Duration & Intensity: Why pKa, lipid solubility, protein binding, and vascularity matter

  • LAST (Local Anesthetic Systemic Toxicity): Early signs, treatment protocols, and real OB case studies

  • Ester vs. Amide: Easy ways to remember which is which - and why it matters

With clinical tips, board exam pearls, and her signature analogies (hello, string vs. power cord 🧵🔌), Chloe helps CRNA students truly understand local anesthetics, not just memorize facts.

📌 Perfect for: SRNAs, CRNAs, nursing students, anesthesia educators, and anyone wanting to solidify their grasp of local anesthetic pharmacology.

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