• E60 Unlocking Potential: The Art of Talent Development
    May 20 2026
    Imagine: you get yourself a sweet new sports car, hop in for your first drive, only to realize you have no idea how to drive stick. So you drive around town in first gear, going super slow, making tons of noise, stalling out at every stop sign. You finally make it home, hop out and proclaim, “This car’s a piece of junk!” Well, that’s the challenge we face with talent development, where the ceiling of your potential — or your team's potential — isn't dictated by innate ability, but by your capacity to unlock it. So to help us learn to shift out of first gear, this episode, we’re joined by Adam Thompson. He’s the Vice Chair of Administration for the Mayo Clinic Comprehensive Cancer Center in Florida. The three big questions we discuss with Adam are: What is talent, and what are we talking about with “talent development?” Why do people and teams fail to develop talent well? What can we do to maximally develop our own talent, as well as that of everyone on the team? Learn more about On Human Optimization and access Pod-Club questions here. Instagram: @MayoHumanOptimizationYouTube: The Human Optimization Project - YouTubeEmail: optimize@mayo.edu Sign up to receive Mayo Clinic Press emails. Find us online at Mayo Clinic Press for more health and wellness articles, podcasts and books. Do you have feedback, questions or topic suggestions? Email us at mcppodcasts@mayo.edu.
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    49 mins
  • E59 The Sleep Paradox: Why Trying Harder Makes It Worse
    May 6 2026
     Why is it that the more we think about falling asleep, the harder it becomes? Our mindset around sleep plays a huge role in our ability to fall asleep, the amount of sleep we get and the quality of that sleep. So how can we use our mindset to our advantage? This episode, we speak with Bhanu Kolla, M.B.B.S., M.D., the co-author of the Mayo Clinic Guide to Better Sleep. He’s also a professor of psychiatry and psychology with clinical appointments in the Center for Sleep Medicine and the Division of Addiction Medicine at Mayo Clinic in Rochester, MN. The three big questions we discuss with Dr. Kolla are: 1. What is the connection between sleep and psychology, and how does that relationship affect our sleep? 2. What are the most common mental traps that negatively impact our sleep? 3. What steps can we take now to optimize our mindset to help us get the best sleep? Learn more about On Human Optimization and access Pod-Club questions at https://ce.mayo.edu/optimize Instagram: @MayoHumanOptimizationYouTube: On Human Optimization - YouTubeEmail: optimize@mayo.edu Sign up to receive Mayo Clinic Press emails. Find us online at Mayo Clinic Press for more health and wellness articles, podcasts and books. Do you have feedback, questions or topic suggestions? Email us at mcppodcasts@mayo.edu.
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    43 mins
  • E58 Being in Charge vs. Being a Leader
    Apr 22 2026
    Just having a title that sounds authoritative doesn’t make someone a leader. And you don’t have to be a CEO to lead, either. So what actually inspires people to take action? In this episode, we’re joined by Thom Mayer, M.D., to explore how to stop waiting for authority and start leading. Dr. Mayer is medical director for the NFL Players Association and author of the book Leadership Is Worthless, but Leading Is Priceless. Here are three questions we explore with Dr. Mayer: What’s the difference between being in charge and being a leader—and why does it matter? Why do so many people struggle to move from boss to leader, and where do they fall short? How can you move beyond managing and start leading, regardless of your title? Learn more about On Human Optimization and access Pod-Club questions here. Instagram: @MayoHumanOptimizationYouTube: The Human Optimization Project - YouTubeEmail: optimize@mayo.edu Sign up to receive Mayo Clinic Press emails. Find us online at Mayo Clinic Press for more health and wellness articles, podcasts and books. Do you have feedback, questions or topic suggestions? Email us at mcppodcasts@mayo.edu.
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    38 mins
  • E57 The State of Flow: How to Maximize
    Apr 8 2026
    Hopefully, you’ve experienced getting so absorbed in work or an activity you enjoy that you lose track of time. We tend to be most productive in what is often called a “state of flow.” When harnessed effectively, flow can act like a superpower for personal fulfillment and progress. To help us better understand and maximize moments of flow, we’re joined by Biju Samkutty, chief operating officer of international and enterprise automation at Mayo Clinic. Known for aligning people, processes and technology, Biju leads Mayo Clinic’s global expansion efforts, including managing international patients, building strategic collaborations and establishing new international entities. In this episode, we explore three key questions: What is the state of flow, and why is it critical for performance and well-being? Why do we struggle to access flow consistently, and how does that impact productivity and happiness? What proven methods can help us maximize flow in daily life and work? Learn more about On Human Optimization and access Pod Club questions here. Sign up to receive Mayo Clinic Press emails. Find us online at Mayo Clinic Press for more health and wellness articles, podcasts and books. Do you have feedback, questions or topic suggestions? Email us at mcppodcasts@mayo.edu.
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    40 mins
  • Tomorrow's Cure - When Algorithms Meet Empathy: The Future of Patient-Centered AI
    Apr 1 2026
    Today, we are sharing an episode from our sister podcast Tomorrow’s Cure. Produced by our Mayo Clinic colleagues, this chart-topping and Ambie Award-finalist podcast explores the future of medicine – from the rise of chronic disease and autoimmune disorders to innovations in AI, 3D bioprinting, and cancer research. In this specific episode, you’ll hear from Mayo Clinic physician leader Dr. Anjali Bhagra and human centered AI expert Dr. Ravi Bapna about how automation and AI are changing the way care teams work, how patients access care, and what it takes to keep people at the center of these advances. Featuring real stories from clinic and hospital settings, this conversation tackles the hard questions around trust, bias, and burnout. You listen to other episodes of Tomorrow’s Cure here: https://play.megaphone.fm/uk0u00jeqjandeotmblt0a
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    50 mins
  • E56 How to Get More Mileage from Your Brain
    Mar 25 2026
    How often do you feel that your brain is functioning at its highest level? If you are like most of us, it’s not as often as you would like. Given the high-pressure world we live in, it’s critical for us to ensure our brain is firing on all cylinders, as often as possible. To make that happen, we need to help our brains be more efficient. Just like mileage on a car, we want to optimize the mileage we get out of our brains. To help us do that, our expert guest today is Dr. Amit Sood, the creator of the Resilient Option program and executive director of the Global Center for Resiliency and Wellbeing. The three questions he is going to walk us through are: 1. What does it mean to "get more mileage" out of our brain, and why are we currently so inefficient? 2. Why is it so hard to stay in "Focused Mode" as our brain tries to pull us towards distraction? 3. What is the solution and what are the specific steps we can take to get the most out of our brains? How to start a Mayo Clinic Human Optimization Project “Pod-Club”: Step 1: Find 2-30 friends who want to get better Step 2: Choose your episodes (can be focused on specific themes or random) Step 3: Listen to/watch the episodes Step 4: Meet with your group to work through the provided discussion questions for each episode, and feel free to add your own! Step 5: Celebrate the fact that you are turning passive knowledge into action! Discussion Questions for this Episode: 1. The podcast defines "getting more mileage out of your brain" as accumulating more experience, learning, insights, and making a difference, rather than just increasing intelligence. How does this broader definition of "brain mileage" resonate with your personal goals for growth and impact? 2. Dr. Sood states that our biggest challenge is our "inability to influence our attention and emotions." In what specific areas of your life do you feel this lack of influence most acutely? 3. The discussion highlights that we spend 60-80% of our time in the "default/automatic mode," which is linked to unhappiness and anxiety. What are some common triggers that pull you into this default mode? 4. The podcast explains that our negativity bias, while once crucial for survival, now often protects our "emotional body." What emotional "threats" do you find yourself constantly guarding against? 5. The concept of "willpower depletion" is linked to poor sleep, nutrition, and lack of exercise. How do your daily lifestyle choices impact your ability to exercise self-control and stay in a focused, intentional mode? 6. Dr. Sood suggests that overthinking occurs when "thinking is happening to you" rather than you choosing your thoughts. What strategies do you currently use, or could you commit to trying this week, to regain control and choose your thoughts more intentionally? 7. The "rum" analogy (Rest, Uplifting emotions, Motivation) is presented as a way to be kind to your mind. Which of these three elements do you find most challenging to incorporate into your daily routine, and why? 8. The podcast suggests that progress in brain optimization can be measured by feeling lighter, less cynical, and experiencing deeper connections. What specific indicators would signal to you that you are successfully "getting more mileage out of your brain"?
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    54 mins
  • Tomorrow's Cure - 3D Bioprinted Skin: Breakthroughs in Regenerative Medicine
    Mar 18 2026
    Today, we are sharing an episode from our sister podcast Tomorrow’s Cure. Produced by our Mayo Clinic colleagues, this chart-topping and Ambie Award-finalist podcast explores the future of medicine – from the rise of chronic disease and autoimmune disorders to new research revealing how early immune changes can develop into certain types of leukemia. In this particular episode, you’ll hear from dermatologist and regenerative medicine expert Dr. Saranya Wyles of Mayo Clinic and biomedical engineer Dr. Adam Feinberg of Carnegie Mellon University about “SkinSpan” and the fast-moving world of 3D bioprinted skin. They explore how layered, living skin models built from human cells and collagen are helping researchers study conditions like eczema, chronic wounds, burns, and age-related changes in skin structure and pigment. You listen to other episodes of Tomorrow’s Cure here: https://play.megaphone.fm/3qwbajhmswc0jz1xfy7dbg
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    41 mins
  • E55 Overcoming Self Doubt and Imposter Syndrome
    Mar 11 2026
    If you’ve ever experienced self-doubt, felt like you didn’t have what it takes, or were fearful of being “found out”, this episode is for you. We have all had the unfortunate experience of improperly doubting ourselves and our abilities to the extent that they had a negative impact on how we feel about ourselves and diminished our performance. Self-doubt and imposter syndrome can be paralyzing, but life is too short for us to live with constant fear and doubt about our abilities. Our expert guest here to help us with this is author and executive consultant, Cade Cowan. The three big questions Cade is going to walk us through are: 1. What exactly is “imposter syndrome”? What are the downsides? 2. How common is self-doubt and how can we tell if it’s impacting us? 3. What steps can we take to overcome imposter syndrome and develop healthy confidence to become our best selves? Host: Christopher L. Camp, M.D., Creator & Guide | Mayo Clinic Human Optimization Project Guest: Cade Cowan, Managing Partner | Executive Development Consulting – Atlanta, GA How to start a Mayo Clinic Human Optimization Project “Pod-Club”: Step 1: Find 2-30 friends who want to get better Step 2: Choose your episodes (can be focused on specific themes or random) Step 3: Listen to/watch the episodes Step 4: Meet with your group to work through the provided discussion questions for each episode, and feel free to add your own! Step 5: Celebrate the fact that you are turning passive knowledge into action! Discussion Questions for this Episode: 1. The podcast distinguishes between imposter syndrome (high competence, low confidence) and low self-confidence (global lack of belief in ability). Think about a time when you experienced one versus the other. How did your actions or feelings differ in those situations? 2. Cade mentions the Dunning-Kruger effect as the opposite of imposter syndrome (low competence, high confidence). How might recognizing both imposter syndrome and the Dunning-Kruger effect help us achieve a more balanced and realistic self-assessment? 3. The discussion highlights the "cycle of imposter syndrome" – a trigger event leading to anxiety, overwork or procrastination, success, and then explaining that success away. Think about a time when you experienced this cycle. What was the most challenging aspect for you? 4. The speakers discuss how environmental factors, such as work culture or societal pressures (like social media's "highlight reels"), can exacerbate imposter syndrome. What specific aspects of your current environment might be contributing to feelings of self-doubt? What is one way you might address this? 5. Cade shares a personal story about presenting to a CEO at 28, realizing he should "stay in his zone of expertise." Consider your own "zone of expertise." What helps you feel comfortable sharing what you don't know in professional or personal settings? 6. The idea of "confident humility" is introduced, emphasizing the ability to say "I don't know" while still being confident in one's ability to learn. How can you practice this balance in your daily interactions? 7. The podcast suggests that imposter syndrome is a "universal experience" and that "everybody else is doing it." How does knowing this change how you interact with others who might be experiencing imposter syndrome? 8. Cade shares his "keepers file" of positive emails and notes. What is one tangible way you could start collecting and revisiting evidence of your own successes and positive impact to combat imposter syndrome? Learn more about the Human Optimization Project at: https://ce.mayo.edu/optimize X: @MayoHumanOpProj Instagram: @MayoHumanOpProj YouTube: The Human Optimization Project - YouTube Email: optimize@mayo.edu
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    58 mins