March 2025: The Impact of Xanomeline and Trospium Chloride on Cognitive Impairment in Acute Schizophrenia: Replication in Pooled Data From Two Phase 3 Trials
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March 2025: The Impact of Xanomeline and Trospium Chloride on Cognitive Impairment in Acute Schizophrenia: Replication in Pooled Data From Two Phase 3 Trials
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About this listen
Dr. William Horan (Bristol Myers Squibb) joins AJP Audio to discuss a newly approved, novel treatment for schizophrenia spectrum disorder, which has potential impacts for cognition in patients. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin puts the rest of the March issue into context.
- 00:45 Horan interview
- 03:15 Novel mechanism of action in the treatment of schizophrenia
- 05:39 Side effect profiles
- 07:20 Clinical impacts
- 08:31 The need for further investigation
- 09:58 Limitations
- 11:05 Further research
- 13:08 Kalin interview
- 13:21 Horan et al.
- 17:34 Levenstein et al.
- 19:00 Fountoulakis et al.
- 20:57 Couture et al.
- 23:18 Stern et al.
- 27:35 McGirr et al.
Transcript
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