This episode does a deep dive into a systematic review and meta-analysis of qualitative evidence concerning barriers and enablers to exercise adherence in individuals with nonspecific chronic low back pain (CLBP). The study synthesizes perceptions and beliefs from 23 papers involving 677 participants, identifying four main themes: exercise, pain, and the body; psychological factors; social factors; and external factors.

Gilanyi YL, Shah B, Cashin AG, et al. Barriers and enablers to exercise adherence in people with nonspecific chronic low back pain: a systematic review of qualitative evidence. Pain. 2024;165(10):2200-2214. doi:10.1097/j.pain.0000000000003234

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This episode does a deep dive into a pragmatic randomized crossover trial investigating the efficacy of in-home HEPA air purifiers in reducing blood pressure for adults residing near highways.

Brugge, D, Eliasziw, M, Thanikachalam, M. et al. Effect of HEPA Filtration Air Purifiers on Blood Pressure: A Pragmatic Randomized Crossover Trial. JACC. 2025. https://doi.org/10.1016/j.jacc.2025.06.037

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This episode dissects a systematic review and meta-analysis exploring the relationship between vitamin D supplementation and Benign Paroxysmal Positional Vertigo (BPPV), a common inner ear disorder causing dizziness. The authors examine existing literature to determine if vitamin D deficiency is associated with BPPV and whether supplementation can reduce its intensity or recurrence.

Hong X, Christ-Franco M, Moher D, et al. Vitamin D Supplementation for Benign Paroxysmal Positional Vertigo: A Systematic Review. Otol Neurotol. 2022;43(7):e704-e711. doi:10.1097/MAO.0000000000003586

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This episode explores the link between sport specialization and injury risk in young athletes, utilizing a bio-emotional social approach. The authors conducted a cross-sectional study with 169 specialized athletes, analyzing self-reported data on sociodemographics, physical attributes, injuries, and psychological factors.

Iona T, Raimo S, Coco D, et al. Specialization and Injury Risk in Different Youth Sports: A Bio-Emotional Social Approach. Front Psychol. 2022;13:818739. Published 2022 Mar 16. doi:10.3389/fpsyg.2022.818739

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This episode provides a comprehensive overview of how the human body, particularly skeletal muscle, changes in response to prolonged exercise. It distinguishes between endurance and strength training, examining their classical definitions, the specific physiological adaptations each induces, and the molecular mechanisms driving these changes.

Hughes DC, Ellefsen S, Baar K. Adaptations to Endurance and Strength Training. Cold Spring Harb Perspect Med. 2018;8(6):a029769. Published 2018 Jun 1. doi:10.1101/cshperspect.a029769

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This episode dissects a clinical trial examining the impact of mouth closure on inspiratory airflow in patients diagnosed with obstructive sleep apnea (OSA).

Yang H, Huyett P, Wang TY, et al. Mouth Closure and Airflow in Patients With Obstructive Sleep Apnea: A Nonrandomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2024;150(11):1012-1019. doi:10.1001/jamaoto.2024.3319

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This episode does a deep dive into an article that explores the complex relationship between the oral microbiome, the gut microbiome, and brain health. The authors investigate how the diverse bacterial communities in the mouth and gut influence overall health and biological aging, particularly in relation to neurological and mental health disorders. They highlight that oral diseases, such as periodontitis, are linked to gastrointestinal issues and can contribute to conditions like Alzheimer's and Parkinson's disease. The paper also examines the significant role of dietary interventions and oral hygiene practices in maintaining a healthy oral-gut-brain axis, suggesting that these could be crucial for disease prevention and promoting healthy aging.

Kerstens R, Ng YZ, Pettersson S, Jayaraman A. Balancing the Oral-Gut-Brain Axis with Diet. Nutrients. 2024;16(18):3206. Published 2024 Sep 22. doi:10.3390/nu16183206

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The article dissected in this episode explores how nutrition plays a crucial role throughout various stages of a woman's life, emphasizing the unique dietary needs during puberty, menarche, fertility, pregnancy, lactation, and menopause. It highlights how hormonal changes significantly impact metabolic processes and nutrient requirements at each phase. The review discusses specific micronutrients and macronutrients essential for optimal health, addresses common health concerns and symptoms associated with each life stage, and suggests tailored dietary strategies, including the use of supplements or traditional remedies, to mitigate adverse effects and improve overall well-being. Ultimately, the paper concludes that proactive and balanced nutritional approaches are fundamental for supporting women's health across their lifespan and reducing the risk of chronic diseases.

Harak SS, Shelke SP, Mali DR, Thakkar AA. Navigating nutrition through the decades: Tailoring dietary strategies to women's life stages. Nutrition. 2025;135:112736. doi:10.1016/j.nut.2025.112736

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