Premenstrual dysphoric disorder (PMDD) approximately affects 2-5% of women around the world. In this episode we have Dr. Liza Kaltsouni, postdoc at Uppsala University, Department of Women's and Children's Health, as an expert in our podcast. During her PhD, Liza Kaltsouni conducted research on PMDD and collected various data, including brain data in the MRI scanner. This has influenced her holistic perspective on PMDD and the multimodal network approach needed to understand this multimodal disorder. In addition to pursuing such a multimodal approach for future research on PMDD, Liza emphasizes the importance of interdisciplinary work and the inclusion of the people for whom the research is intended. Following the motto “nothing good is easy”, Liza calls on us to listen more. And you can start today - by listening to this enlightening conversation!

Timestamps:

00:27 Introduction of our guest Dr. Liza Kaltsouni & her field of research

01:46 What is premenstrual dysphoric disorder (PMDD) and how is it differed to premenstrual syndrome (PMS) ?

05:57 What do we know about underlying causes of PMDD?

12:13 Hormonal sensitivity hypothesis

18:22 What do we know about PMDD & brain structure + function?

27:57 Multimodal study project & findings of Liza Kaltsouni

37:55 Implications of Liza's research

41:10 Current available treatment for PMDD

44:59 Outlook: Upcoming treatment possibilities for PMDD?

48:50 Summary

52:27 Closing remarks & future directions in research

Want to get in touch with Liza?

elisavet.kaltsouni@uu.se

https://www.uu.se/en/contact-and-organisation/staff?query=N19-2428

Sound recording: Franziska Weinmar at Recording Studio Blasenhus, Uppsala University

Editing: Franziska Weinmar

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