Impulse - Meeting Healthcare Pioneers cover art

Impulse - Meeting Healthcare Pioneers

Impulse - Meeting Healthcare Pioneers

By: Mathieu Chaffard
Listen for free

About this listen

 Impulse is the podcast where we dive into the most exciting breakthroughs in healthcare of our time. In each episode, we sit down with some of the brightest minds who are using technology to rethink the way we care!Mathieu Chaffard Career Success Economics Hygiene & Healthy Living Physical Illness & Disease
Episodes
  • #56 - Building the one clinical AI assistant - Ali Parsa - Quadrivia

    #56 - Building the one clinical AI assistant - Ali Parsa - Quadrivia
    Dec 10 2025
    What will our interactions with our healthcare system look like in the age of AI? Whether you are a patient, a doctor, or any other stakeholder in that system, the question is worth asking. In a world where healthcare costs continue to skyrocket, it is clear we need a radical solution to reverse the trend. The broader challenge is to restore the balance between demand and supply of care, limited by our capacity to train new doctors. Among those relentlessly working on this task are Ali Parsa and his team at Quadrivia. A true veteran of healthcare entrepreneurship, Ali founded Circle Health Group, now the largest chain of private hospitals in the UK, and Babylon Health, the fallen European digital health unicorn that once pioneered the use of AI for remote medicine, symptom checking, and patient triage. Despite all the highs and lows and whatever may have been said about his journey, Ali remains driven by the same mission: making healthcare more accessible and affordable at scale. Today, his efforts are focused on building Qu, which he aims to establish as the gold standard for clinical AI assistants, serving patients, doctors, and the broader ecosystem of actors in the space. In this episode, Ali reveals the inner workings of this formidable tool, showcasing its ability to automate repetitive tasks that healthcare professionals face daily, and the opportunity it offers patients by being available around the clock to advise, educate, and ensure continuous medical supervision. We also discuss the key role of healthcare professionals in the validation of Qu, how to approach the risks and European regulations to make it widely available, and finally, the time and caution required to confidently integrate AI into patients' lives and routine clinical practice. A fascinating conversation that outlines the future of our interactions with the healthcare world! Timeline: 00:00:00 - Ali’s journey as an entrepreneur building healthcare institutions and digital health solutions 00:11:52 - Why healthcare is not affordable nor accessible in the current system 00:16:17 - The interactions where AI will play a crucial role in healthcare (including a demo of Qu!) 00:25:06 - An approach to validate clinically the behaviour of AI in healthcare 00:29:54 - Ali’s observations on the current struggles around AI regulation in healthcare 00:37:22 - Making AI customisable to accommodate different clinical care practices for similar use cases 00:40:01 - Judging a clinical AI’s performance relative to the real performance of healthcare professionals 00:45:10 - Ali’s ambition and Quadrivia’s plans for the next few years What we also talked about with Ali: Special Purpose Acquisition Company (SPAC) Bakul Patel FDA Lovable Modality Partnership We cited with Ali some of the past episodes of the series: #47 - Pushing responsible AI in health - Dr. Ricardo Baptista Leite - HealthAI As mentioned by Ali during the episode, you can have a read at Thinking Machines Lab’s publication “Defeating Nondeterminism in LLM Inference” from September 2025, to dive deep into the nondeterminism problem around the use of LLMs. You can get in touch with Ali via LinkedIn, and follow Quadrivia’s activities on their website and on LinkedIn. ✉️ If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! ⭐️ And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 You can also support my work by doing a PayPal donation @ImpulsePodcast! 👍 Lastly, don’t forget to follow our activities on LinkedIn and our website!
    Show More Show Less
    55 mins
  • [SNIPPET] - Ali Parsa on ways to validate AI models in clinical practice

    [SNIPPET] - Ali Parsa on ways to validate AI models in clinical practice
    Dec 9 2025
    To discover the whole episode, type "#56 - Building the one clinical AI assistant - Ali Parsa - Quadrivia" on your preferred streaming platform.
    Show More Show Less
    7 mins
  • #55 - Reinventing organ transportation - Lisa Anderson - Paragonix Technologies

    #55 - Reinventing organ transportation - Lisa Anderson - Paragonix Technologies
    Nov 30 2025
    Do you know how organs are traditionally transported for transplantation purposes? In a cooler filled with ice. When I learned that this approach was the most widespread method, I admit I was quite shocked... We talk here about "living" organs whose preservation is crucial for the success of their transplant! And as you can imagine, these transplants are often vital. The good news is: some people have racked their brains and rolled up their sleeves to change all that! And one of them is none other than Lisa Anderson, Co-Founder and President of Paragonix Technologies. With her team, she has literally redefined how organs could be transported, wiping the slate clean of an archaic, despite standard method. Last year, their technology was named one of TIME’s 200 Best Inventions in the Medical Care category. A technology that allows organs to be preserved and monitored under ideal conditions of temperature, pressure, and perfusion. Since its creation in 2010, the company has enabled the transport of over 10,000 hearts, lungs, kidneys, livers, and pancreases combined to date. A paradigm shift, which not only allows for better preservation of these tissues during transport but is also accompanied by a surprising improvement in transplant outcomes, and helps democratise access to them. We talk about all of this with Lisa, from the complexity of developing such a system to the change management required to lead to its acceptance in the medical field. And everything that this changes for the patients who benefit from it every day. A conversation that dusts off a long-established medical practice and lifts the veil on a unique MedTech success story! Timeline: 00:00:00 - How Lisa got into the transplantation and organ transportation space 00:05:54 - The criticality of organ preservation before a graft 00:08:27 - The parameters to control when transporting organs 00:11:38 - The benefits of improved organ preservation on graft success 00:19:01 - Paragonix Technologies’ clients and commercial models 00:21:20 - Sustainability considerations in the organ transportation business 00:25:29 - Paragonix Technologies’ plans for geographic expansion 00:28:00 - The journey from A to Z of an organ between its donor and recipient 00:30:56 - Changing practices and mindsets around organ transportation 00:33:20 - The engineering challenges around the creation of Paragonix Technologies’ first products 00:40:07 - Matching better the demand and supply of organ transplants What we also talked about with Lisa: Getinge As mentioned by Lisa during the episode, you can have a read at Paragonix Technologies’ latest publications here and find out more about their products and technology on their website. You can get in touch with Lisa via LinkedIn, and follow Paragonix Technologies’ activities on LinkedIn, X, Facebook, and YouTube. ✉️ If you want to give me feedback on the episode or suggest potential guests, contact me over LinkedIn or via email! ⭐️ And if you liked the episode, please share it, subscribe to the podcast, and leave a 5-star review on streaming platforms! 🙏 You can also support my work by doing a PayPal donation @ImpulsePodcast! 👍 Lastly, don’t forget to follow our activities on LinkedIn and our website!
    Show More Show Less
    48 mins
No reviews yet
In the spirit of reconciliation, Audible acknowledges the Traditional Custodians of country throughout Australia and their connections to land, sea and community. We pay our respect to their elders past and present and extend that respect to all Aboriginal and Torres Strait Islander peoples today.