Is you diagnosis precise, correct, and complete? 

Is your treatment plan perfect?

Get answers here:

https://diagnosticdetectives.com/

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Conversation with Prof. Scott L. Friedman [Mount Sinai School of Medicine, New York]

https://diagnosticdetectives.com/liver/friedman/

Causes, diagnosis, treatment of NAFLD and NASH. Genetic tests. Supplements and generic drugs for NASH. Liver cancer risk. Coffee helps liver health. On importance of having a good mentor.

00:00 Biography: Liver expert, Prof. Scott L. Friedman

01:33 What is Fatty Liver Disease [NAFLD]? 

04:17 Non-obese patients with NAFLD. 

05:29 Diagnostic tests for NAFLD. 

06:31 Normal ALT, AST but bad NASH or NAFLD

07:40 FibroScan, MR Elastography to test for liver fibrosis

08:18 Can NAFLD be reversed?

09:34 How NASH differs from NAFLD?

10:16 What drives progression to NASH?

11:40 Genetic tests for risks of liver disease?

12:33 Microbiome and NAFLD / NASH?

14:09 Antibiotics in food lead to NAFLD / NASH.

16:06 ‘Auto-brewery syndrome’: gut makes alcohol?

17:56 Fecal microbiome transplantation for NASH?

20:29 Supplements and generics for NASH

20:48 Pharma is not interested in generics or supplements for NASH.

22:27 Hepatic Stellate Cells cause NAFLD / NASH?

28:30 Liver cancer and NASH / NAFLD?

32:03 How to personalize liver cancer screening in NASH?

34:27 Why no drugs approved for NASH?

38:28 Leading drug candidates for NASH therapy.

42:38 Repurposing generics for NASH therapy.

44:06 Statins for NASH and Heart risks?

45:00 Most NASH / NAFLD patients have NO symptoms

46:15 Coffee and liver health?

46:45 Coffee reduces risks of liver disease

48:13 Future of liver disease treatment.

49:56 Xenotransplantation for liver disease

51:15 Regeneration of liver: greatest mystery! 

52:17 Questions of patients with liver disease.

53:51 ‘No symptoms but advanced liver disease’

54:12 How to improve liver health?

54:30 Weight loss is best therapy for NASH / NAFLD

55:22 Patients’ fear: no symptoms but bad liver disease?

55:54 Alcohol rarely causes NAFLD / NASH

56:42 ‘Mentorship is key to successful career’ - Prof. Friedman

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