Welcome back to Health Unlocked! In today’s episode, Jasen Petersen explores a fascinating and refreshingly practical side of health innovation: how medical devices like IBAL are rewriting the rules of bringing new interventions to market. If you’ve ever wondered why some health-supporting products aren’t classified as drugs or supplements, or how the FDA draws that crucial line, you’ll love this discussion.

Jasen, speaking from both professional and personal experience (post-lithotripsy, no less - ouch!), walks us through the surprising world of medical device regulation. He explains why IBAL, a micronutrient matrix designed to restore foundational cellular health, qualifies as a medical device rather than a drug and why that distinction could make innovative treatments far more accessible, affordable, and fast to reach those who need them most.

Along the way, you’ll hear about strange regulatory quirks (like how toothpaste can be a cosmetic, a drug, or a device!), learn what it truly means for something to have a “PMI mechanism,” and get a behind-the-scenes look at how shifting the regulatory path from drugs to devices could transform healthcare innovation for both patients and investors.

By the end, you’ll have a whole new appreciation for how creative science, regulatory strategy, and a bit of bold thinking can work together to unlock better health for everyone. Let’s dive in!

Timestamps:

00:00 "IBAL: Redefining Medical Regulations"

04:23 "Foundations of Immune Healing"

08:50 Drug vs. Device Development Timelines

11:01 Drug vs Device Development Differences

15:20 Biotech Confidence in Non-PMI Drugs

20:01 IBAL Ingestion Risks and Alternatives

23:30 "Possibilities for Medical Innovation"

27:43 "Medical Device Outperforming Drugs"

28:48 Drug vs. Device Approval Risks

32:46 "Ion Gel Medical Device Approval"

36:07 Tokenized Research for Immune Continuum

39:26 "Grateful Acknowledgment"

“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Show Website - https://powerofsalutogenesis.com/

Ionic Alliance Foundation Website - https://iaf.care/

Jasen Petersen's LinkedIn - https://www.linkedin.com/in/jasenepetersen/

TopHealth Media Website - https://tophealth.care/

Welcome back to Health Unlocked! In this episode, Jasen Petersen dives into the fascinating world of decentralized science, or DeSci, and explores how it could revolutionize medicine as we know it. With trust in traditional health institutions and pharmaceutical companies at an all-time low, this conversation opens up new possibilities for how drugs and therapies can be developed, funded, and governed.

Jasen breaks down what DeSci actually means, drawing parallels to decentralized finance (DeFi) and blockchain technology, and explains how shifting decision-making and funding power from centralized gatekeepers to communities could make drug development faster, more open, and more affordable. He discusses the potential benefits for contributors, the role of DAOs (Decentralized Autonomous Organizations), and how transparency and democratization could reshape outcomes: not just in research, but for real-world patients.

Using the case of Ionic Alliance and the innovative ion-based wound gel, the hosts illustrate how DeSci models could offer tangible paths to market, bypassing conventional hurdles and sharing both governance and potential rewards with the community.

Of course, no new model is without risks, and Jasen doesn’t shy away from discussing the potential pitfalls, including whether DeSci could simply repackage old problems in new wrappers. He wraps up with a look at the future: what medicine could look like if DeSci truly takes off, and why the journey is just beginning.

Whether you’re a healthcare innovator, a curious patient, or just interested in the intersection of blockchain and biotech, this episode is packed with insights you won’t want to miss!

Timestamps:

00:00 Streamlining Science with Smart Contracts

04:01 Decentralized Approach to Faster Science

08:21 DAO Tokens: Governance, Not Ownership

11:12 Decentralized Research Funding Revolution

13:39 Biotech Breakthrough: Fundable Eyeball Ion Theory

16:37 Decentralized Science: Early Challenges

20:23 Decentralized Science Needs Practical Solutions

26:12 "Guidance vs. ROI Projects"

29:12 Decentralized Funding for Medical Device Approval

31:23 NFTs in Regulatory Approvals

34:00 Transparent Medicine and On-Chain Development

39:06 Exploring Eyeball and Similar Projects

41:42 Appreciation for Blockchain Insights

“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Show Website - https://powerofsalutogenesis.com/

Ionic Alliance Foundation Website - https://iaf.care/

Jasen Petersen's LinkedIn - https://www.linkedin.com/in/jasenepetersen/

TopHealth Media Website - https://tophealth.care/

Welcome back to Health Unlocked! In this episode, Jasen Petersen dives deep into a fresh and holistic approach to understanding health, unveiling a concept Jasen has coined as “micro immune dynamics.” The discussion begins with a personal reflection on summer, parenting, and fostering kids’ creativity, before shifting gears to explore why traditional models of immunity and healing often feel incomplete.

Jasen breaks down the need for a new, unified language to describe the dynamic interplay between immune cells, local nutrients, tissue function, and even resident microbes, all at the micro level where real health and repair begin. They reveal how the micro immune dynamics framework reshapes our approach to chronic illness, inflammation, and even everyday wellness, urging us to move from a reactive to a truly salutogenic strategy.

The episode contrasts current conventional and integrative medical models with this new approach, showing how symptom-driven, terrain-focused interventions can often outpace both systemic drugs and standard diagnostics. Jasen offers real-world signs that our internal terrain may be off balance (long before lab tests catch it), and hands out practical examples and actionable strategies.

Plus, discover how innovative solutions like ion biotechnology and the product IBAL fit into this model, targeting core imbalances to support true, lasting healing. Whether you’re a practitioner or simply navigating your own health, this episode is packed with insight, new language, and a mapping tool for your wellness journey.

Timestamps:

00:00 Youth Entrepreneurial Show Challenge

05:43 Cratogenic Term Explains Drug Breakdown

08:03 "Micro Immune Dynamics: Unified Health Framework"

11:16 "Micro Immune Dynamics in Tissue Health"

15:40 Integrative Microbiome and Diet Therapy

18:13 "Micro Immune Restoration First"

23:03 Cancer Treatment Missteps and Challenges

24:00 Addressing Intracellular Fungal Infections

28:19 "Integrative Remedies Before Antibiotics"

32:51 Subclinical Symptoms and Health Clues

34:15 Spotting Health Imbalance Signals

40:37 Micro Immune Exhaustion and Systemic Signs

42:56 "Nutrient Deficiency Mimics Immunocompromise"

47:21 Salutogenic Restoration for Antibiotic Use

53:16 Micro Immune Restoration via Ion Biotechnology

55:02 Discovering Mechanisms of Healing Effects

58:31 "Expanding Micro Immune Dynamics"

“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Show Website - https://powerofsalutogenesis.com/

Ionic Alliance Foundation Website - https://iaf.care/

Jasen Petersen's LinkedIn - https://www.linkedin.com/in/jasenepetersen/

TopHealth Media Website - https://tophealth.care/

Welcome back to Health Unlocked, where we dive deep into the science and strategies behind living a truly healthy, resilient life. In this episode, Jasen Petersen celebrates a milestone of over 50,000 downloads and takes a journey into the hot topic of metabolic flexibility, a concept that’s buzzing in both the health and biohacking worlds but is often misunderstood.

Jasen breaks down what metabolic flexibility really means, moving beyond oversimplified discussions about diets like keto or fasting, and into how our mitochondria, the energy powerhouses of our cells, adapt to different fuel sources. He discusses why adaptability, not just optimization, is crucial, especially when it comes to battling chronic disease and recovering from stress or illness.

Throughout the episode, you’ll learn how metabolic flexibility is lost, why simply burning fat isn’t enough, the pitfalls of “carb-cutting” trends, and why true resilience comes from restoring your body’s ability to seamlessly switch between energy sources. Whether you’re dealing with chronic illness, striving to improve your health, or just curious about how movement, nutrition, and mitochondrial function all connect, this conversation offers plenty of science-backed insights and practical takeaways.

So grab your headphones, get ready for some myth-busting, and discover how you can start cultivating a “salutogenic” (health-promoting) lifestyle, one mitochondrion at a time!

Timestamps:

00:00 Understanding Metabolic Flexibility

06:25 Metabolic Flexibility vs. Fat Adaptation

10:58 Hybrid Car Glucose-Fat Analogy

20:09 Metabolic Rigidity and Glycolysis Dynamics

26:46 Metabolic Flexibility and Mitochondrial Health

27:55 Carb Intake Simplification Misconception

37:48 Humans: Endurance Runners of Nature

40:48 "Macrophage Metabolism and Immune Flexibility"

45:02 Reevaluating Cancer Treatment Approach

50:37 "Glutaminolysis: Risks in Energy Metabolism"

55:22 Challenges of Long-Term Veganism

01:03:13 Grass vs. Grain-Fed Beef Debate

01:07:15 Metabolic Flexibility and Health Signals

“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Show Website - https://powerofsalutogenesis.com/

Ionic Alliance Foundation Website - https://iaf.care/

Jasen Petersen's LinkedIn - https://www.linkedin.com/in/jasenepetersen/

TopHealth Media Website - https://tophealth.care/

Welcome back to Health Unlocked! In this episode, host Jasen Petersen dives into the fascinating topic of "community as medicine," exploring the essential role that social connection plays in our healing and overall well-being. Drawing from evolutionary biology, lived experiences at Eudaimonia (Jasen’s wellness community), and real-world examples like Blue Zones, they reveal how our brains are deeply wired for connection, and how isolation isn't just an emotional burden, but a true biological stressor that can affect everything from our immune system to our cellular health.

Jasen shares powerful insights into how supportive environments, whether in-person or even virtual, can dial down the body’s threat responses, paving the way for genuine healing and growth. Along the way, they discuss the hidden impacts of modern lifestyles, why support groups work, and how even AI companions might play a surprising role in fostering salutogenesis (a framework that focuses on factors contributing to health and well-being, rather than solely on disease and illness). As the world gets busier and more isolated, this conversation will challenge how you view health, healing, and the importance of finding your tribe.

Tune in to discover why community might just be the most powerful "biohack" of all, and how you can start leveraging it in your own life.

Timestamps:

00:00 Apologizing for Potential Noise

05:44 Brain's Somatic Threat Mapping

07:40 "Social Ties and Neuroimmune Response"

12:26 Navigating Modern World Overload

17:36 Community Growth Through Connection

20:13 Brain's Healing and Growth Cycle

23:46 Loma Linda's Lifestyle Longevity Secrets

26:04 "Blue Zones: Natural Wellbeing Cultures"

30:26 Body's Response to Perceived Threats

33:29 "Community Aids Healing Process"

36:11 AI's Impact on Social Perception

40:32 Body's Decision Process

41:41 Chronic Stress Overload Harms Brain

45:47 Biohacking and Unnoticed Benefits

48:35 "Scaling Online Community Goals"

“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Show Website - https://powerofsalutogenesis.com/

Ionic Alliance Foundation Website - https://iaf.care/

Jasen Petersen's LinkedIn - https://www.linkedin.com/in/jasenepetersen/

TopHealth Media Website - https://tophealth.care/

Welcome back to Health Unlocked! In this episode, host Jasen Petersen has an eye-opening discussion that peels back the layers, literally, of the immune system. After catching up on alumni volleyball adventures and conference buzz, the conversation dives deep into why the phrase “support the immune system” is dangerously imprecise and how most of us misunderstand what immunity support actually means.

Jasen unpacks the concept of a “layered immune system,” revealing why focusing on specific layers, like the often-overlooked local innate immune system, is key to real healing and resilience, especially in the face of chronic disease. The show also explores the strengths and blind spots of the Integrative Functional Medicine (IFM) model, how precision medicine is (and isn’t) making headway, and practical ways practitioners and listeners can identify which “immune layers” their current strategies are really supporting.

Plus, Jasen shares compelling personal stories and real-world insights, including how tools like Lumen are changing the way we measure metabolic flexibility and support whole-body healing. Whether you’re a health professional or simply curious about what it really takes to unlock lifelong wellness, this episode will change the way you think about integrative medicine, chronic illness, and immune health.

Timestamps:

00:00 "Local Innate Immunity's Importance"

06:12 Systemic Innate Immunity Explained

11:36 Integrative Protocols: Incomplete Solutions

18:38 "ATP: Energy and Signal Dilemma"

26:57 "Prioritizing Local Immune Support"

31:17 Shingles and Immune Response Explained

35:02 Apoptosis vs. Necrosis in Healing

43:51 "Targeting Immune Layers in Medicine"

44:58 Immune System Workouts: Probiotics & Cold Therapy

53:37 "Challenges of Optimizing Chronic Health"

56:52 Metabolic Flexibility and Fasting Insights

01:01:11 "Episode Conclusion & Thanks"

“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Show Website - https://powerofsalutogenesis.com/

Ionic Alliance Foundation Website - https://iaf.care/

Jasen Petersen's LinkedIn - https://www.linkedin.com/in/jasenepetersen/

TopHealth Media Website - https://tophealth.care/

Welcome back to Health Unlocked: The Power of Salutogenesis, where we explore the science and mystery behind healing and what it really means to achieve lifelong wellness. In this episode, host Jasen Petersen dive deep into a groundbreaking perspective on aging - not as inevitable wear and tear, but as a process of "unfinished healing."

Jasen unpacks the cell danger response (CDR) cycle and reveals how stress, both physical and emotional, can interrupt our body’s natural repair processes at the cellular level. Instead of seeing aging as just decline, Jasen shares research from Dr. Naviaux and others to reframe it as a backlog of repairs the body was never quite able to finish - leaving behind so-called "senescent" cells that subtly fuel dysfunction over time.

The conversation goes further, exploring why persistent stress leads to cellular roadblocks, how chronic pain and lingering injuries are signals of incomplete healing, and why most of us "don’t bounce back" as quickly in later years. You'll also hear about the emerging promise of salutogenic therapies designed to support the body’s self-repair - and why targeted cellular support, like Jasen’s own product “IBAL”, is at the cutting edge of anti-aging and preventative health.

Whether you’re interested in the science of longevity, new perspectives on daily wellness, or practical tips for supporting your body’s natural healing cycles, this episode is full of fascinating insights that will change the way you think about health and aging. Join us as we unlock the keys to healthier, more resilient living!

Timestamps:

00:00 Cell Cycle Disruption and Aging

08:56 Cellular Dysfunction and Healing Reset

12:40 Emotional vs. Physical Stress Response

18:38 Cell Cycle Stagnation in Aging

25:03 Senescence: Protective Yet Dysfunctional Cells

27:35 Immune System and Cellular Senescence

32:32 Senescent Cells and Healing Impairment

39:20 Restoring Body's Natural Healing Ability

43:01 Understanding Salutogenics vs. Kratogenics

49:41 Salutogenic Aging Therapy Evolution

57:06 Fast-Absorbing Immune Booster

58:29 Microbiome Health: Balancing Good and Bad Bacteria

01:05:24 Balancing Action and Resource Use

01:09:54 "Purchase Info Available Online"

“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Show Website - https://powerofsalutogenesis.com/

Ionic Alliance Foundation Website - https://iaf.care/

Jasen Petersen's LinkedIn - https://www.linkedin.com/in/jasenepetersen/

TopHealth Media Website - https://tophealth.care/

Welcome to another compelling episode of Health Unlocked: The Power of Salutogenesis, where host Jasen Petersen dive deep into the challenges of bringing innovative healthcare solutions to the world. In today's episode, we cover our core theme around the cost of doing good, and how hard it is to help people. Jasen navigates the complex maze of bureaucratic nightmares and unexpected hurdles faced by revolutionary ventures like Eudaimonia and IBAL.

Jasen opens up about the relentless fight against a system designed more for profit than for curing diseases. He shares personal stories of sacrifices, from losing the house his father built to battling those trying to control his proprietary innovations.

This episode offers an eye-opening perspective on resisting a profit-oriented healthcare system and striving to build something meaningful beyond it. Get ready to explore how resilience, vision, and a community-driven approach can make an indelible impact in the world of health. Whether you're a healthcare provider, investor, or someone passionate about making a difference, this episode will undoubtedly pique your interest. Stay tuned and join us on this transformative journey.

Timestamps:

00:00 Navigating Credibility in Digital Age

06:07 "Eudaimonia: Vision of Human Flourishing"

11:02 Unexpected Zoning Issue Delays Business

16:26 Case Management Challenges and Rezoning

26:41 "Lost Cancer Remedy Led to Tragedy"

30:32 Shifting Blame for Bold Claims

37:08 Inventor Exploited by Lawyers?

42:21 "Resilience Against Systemic Challenges"

44:19 Trusting in People Despite Risks

53:41 Mission-Driven Biotech Approach

58:17 Transparent Investments in Ion Gel Innovation

01:04:36 "Global Distribution & Development Strategy"

01:07:23 Bureaucratic Battle for Intellectual Property

“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”

Show Website - https://powerofsalutogenesis.com/

Ionic Alliance Foundation Website - https://iaf.care/

Jasen Petersen's LinkedIn - https://www.linkedin.com/in/jasenepetersen/

TopHealth Media Website - https://tophealth.care/