Episode 960: Frank's Sign - A Marker for Coronary Artery Disease
Failed to add items
Sorry, we are unable to add the item because your shopping cart is already at capacity.
Add to basket failed.
Please try again later
Add to Wish List failed.
Please try again later
Remove from Wish List failed.
Please try again later
Follow podcast failed
Unfollow podcast failed
Episode 960: Frank's Sign - A Marker for Coronary Artery Disease
-
Narrated by:
-
By:
About this listen
Contributor: Travis Barlock MD
Educational Pearls
- Frank’s sign is a curious physical exam finding first described in the literature in 1973
- Bilateral earlobe creases are recognized as a marker of coronary artery disease and cerebrovascular disease
- Some studies have found an increase in all-cause mortality in patients with bilateral diagonal earlobe creases
- The pathophysiology is still not fully understood
- One 2020 study found histopathological changes associated with diagonal earlobe creases, potentially linking them via a model of hypoxia/reoxygenation
References
- Elliott WJ, Karrison T. Increased all-cause and cardiac morbidity and mortality associated with the diagonal earlobe crease: a prospective cohort study. Am J Med. 1991;91(3):247-254. doi:10.1016/0002-9343(91)90123-f
- Nazzal S, Hijazi B, Khalila L, Blum A. Diagonal Earlobe Crease (Frank's Sign): A Predictor of Cerebral Vascular Events. Am J Med. 2017;130(11):1324.e1-1324.e5. doi:10.1016/j.amjmed.2017.03.059
- Stoyanov GS, Dzhenkov D, Petkova L, Sapundzhiev N, Georgiev S. The Histological Basis of Frank's Sign. Head Neck Pathol. 2021;15(2):402-407. doi:10.1007/s12105-020-01205-4
Summarized & Edited by Jorge Chalit, OMS4
Donate: https://emergencymedicalminute.org/donate/
What listeners say about Episode 960: Frank's Sign - A Marker for Coronary Artery Disease
Average Customer RatingsReviews - Please select the tabs below to change the source of reviews.
In the spirit of reconciliation, Audible acknowledges the Traditional Custodians of country throughout Australia and their connections to land, sea and community. We pay our respect to their elders past and present and extend that respect to all Aboriginal and Torres Strait Islander peoples today.