​​Are You Picking the Wrong KOLs? cover art

​​Are You Picking the Wrong KOLs?

​​Are You Picking the Wrong KOLs?

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Darshan Kulkarni and Edye Edens tackle the complexities of identifying and working with Key Opinion Leaders (KOLs) in clinical research. While KOLs can bring valuable expertise to a therapeutic area, simply labeling someone as a KOL—especially when they self-identify—can raise significant compliance concerns.

They unpacks two major red flags:

  1. High Prescribers – Is the KOL being compensated for research or for prescribing power?

  2. Influencer Effect – Are they being used to sway other physicians’ prescribing behavior?

They also highlight issues with KOL selection based on outdated reputation or academic status rather than real-time operational capacity. Choosing the wrong KOL—one who can’t meet documentation or compliance standards—can derail your site’s performance.

Key takeaway:
Don't focus on titles—focus on capability, compliance, and fit. Avoid the label "KOL" and instead qualify experts based on their patient databases, research experience, and operational readiness.

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