Epigenetics is the science of living DNA, charting the chemical pathways that spur DNA into action by turning genes on and off. While the Human Genome Project of the early 2000s was hailed as the key to understanding human heredity and disease, that historic effort was just the beginning. It has taken epigenetics to fill in the picture, explaining how the fixed code of our genome is implemented in countless living processes.

In Mitochondria and the Future of Medicine, naturopathic doctor Lee Know tells the epic story of mitochondria - the widely misunderstood and often-overlooked powerhouses of our cells. The legendary saga began over two billion years ago, when one bacterium entered another without being digested, which would evolve to create the first mitochondrion. Since then, for life to exist beyond single-celled bacteria, it's the mitochondria that have been responsible for this life-giving energy.

Why does your weather app say “there’s a 10 percent chance of rain” instead of “it will be sunny”? In large part, this is due to the insight of award-winning physicist Tim Palmer, who pioneered the introduction of uncertainty into weather and climate prediction. Now, he wants to apply it to how we study everything else.

The burgeoning new science of epigenetics offers a cornucopia of insights - some comforting, some frightening. For example, the male fetus may be especially vulnerable to certain common chemicals in our environment, in ways that damage not only his own sperm but also the sperm of his sons. And it’s epigenetics that causes identical twins to vary widely in their susceptibility to dementia and cancer. But here’s the good news: unlike mutations, epigenetic effects are reversible. Indeed, epigenetic engineering is the future of medicine.

To understand the roots of personality is to understand motivations and influences that shape behavior, which in turn reflect how you deal with the opportunities and challenges of everyday life. That's the focus of these exciting 24 lectures, in which you examine the differences in people's personalities, where these differences come from, and how they shape our lives. Drawing on information gleaned from psychology, neuroscience, and genetics, Professor Leary opens the door to understanding how personality works and why.