Showing titles in Evolution & Genetics

High in the Canadian Rockies is a small limestone quarry formed 530 million years ago called the Burgess Shale. It holds the remains of an ancient sea where dozens of strange creatures lived—a forgotten corner of evolution preserved in awesome detail. In this book, Stephen Jay Gould explores what the Burgess Shale tells us about evolution and the nature of history.

We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often - 200 times more often than a dog does? How come our wrists have so many useless bones? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last.

In the spring of 2012, the Berkeley biochemist Jennifer Doudna and her collaborators turned a curiosity of nature into an invention that will transform the future of the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. It has already been deployed to cure deadly diseases, fight the coronavirus pandemic of 2020, and make inheritable changes in the genes of babies.

Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases.

In a book that is both groundbreaking and accessible, Daniel C. Dennett, whom Chet Raymo of The Boston Globe calls "one of the most provocative thinkers on the planet", focuses his unerringly logical mind on the theory of natural selection, showing how Darwin's great idea transforms and illuminates our traditional view of humanity's place in the universe. Dennett vividly describes the theory itself and then extends Darwin's vision with impeccable arguments to their often surprising conclusions, challenging the views of some of the most famous scientists of our day.

Biology is undergoing a quiet but profound transformation. Several aspects of the standard picture of how life works—the idea of the genome as a blueprint, of genes as instructions for building an organism, of proteins as precisely tailored molecular machines, of cells as entities with fixed identities, and more—have been exposed as incomplete, misleading, or wrong. In How Life Works, Philip Ball explores the new biology, revealing life to be a far richer, more ingenious affair than we had guessed.

In this landmark book of popular science, Daniel E. Lieberman - chair of the department of human evolutionary biology at Harvard University and a leader in the field - gives us a lucid and engaging account of how the human body evolved over millions of years, even as it shows how the increasing disparity between the jumble of adaptations in our Stone Age bodies and advancements in the modern world is occasioning this paradox: greater longevity but increased chronic disease.

Over the last half a billion years, there have been five mass extinctions of life on earth. Scientists around the world are currently monitoring the sixth, predicted to be the most devastating extinction event since the asteroid impact that wiped out the dinosaurs. Elizabeth Kolbert combines brilliant field reporting, the history of ideas and the work of geologists, botanists and marine biologists to tell the gripping stories of a dozen species – including the Panamanian golden frog and the Sumatran rhino – some already gone, others at the point of vanishing.

Epigenetics is the science of living DNA, charting the chemical pathways that spur DNA into action by turning genes on and off. While the Human Genome Project of the early 2000s was hailed as the key to understanding human heredity and disease, that historic effort was just the beginning. It has taken epigenetics to fill in the picture, explaining how the fixed code of our genome is implemented in countless living processes.

Why did humans abandon hunting and gathering for sedentary communities dependent on livestock and cereal grains and governed by precursors of today's states? Most people believe that plant and animal domestication allowed humans, finally, to settle down and form agricultural villages, towns, and states, which made possible civilization, law, public order, and a presumably secure way of living. But archaeological and historical evidence challenges this narrative.

We are a wonder of evolution. Powerful yet dextrous, instinctive yet thoughtful, we are expert communicators and innovators. Our exceptional abilities have created the civilisation we know today. But we're also deeply flawed. Our bodies break, choke and fail, whether we're kings or peasants. Diseases thwart our boldest plans. Our psychological biases have been at the root of terrible decisions in both war and peacetime. This extraordinary contradiction is the essence of what it means to be human - the sum total of our frailties and our faculties.

Challenging leading scientific theories that claim that our senses report back objective reality, cognitive scientist Donald Hoffman argues that while we should take our perceptions seriously, we should not take them literally. How can it be possible that the world we see is not objective reality? And how can our senses be useful if they are not communicating the truth? Hoffman grapples with these questions and more over the course of this eye-opening work.

For the first time in over ten millennia, the rate of human population growth is slowing down. The global population is forecast to begin declining in the second half of this century, and in 10,000 years’ time, our species will likely be extinct.

We are capable of savage acts of violence but also spectacular feats of kindness: is one side of our nature destined to win out over the other? Every act of human behaviour has multiple layers of causation, spiralling back seconds, minutes, hours, days, months, years, even centuries, right back to the dawn of time and the origins of our species. In the epic sweep of history, how does our biology affect the arc of war and peace, justice and persecution? How have our brains evolved alongside our cultures?

Known as the ‘four horsemen’ of New Atheism, these four big thinkers of the 21st century met only once. Their electrifying examination of ideas on this remarkable occasion was intense and wide-ranging. Everything that was said as they agreed and disagreed with one another, interrogated ideas and exchanged insights - about religion and atheism, science and sense - speaks with urgency to our present age.

Nessa Carey’s The Epigenetics Revolution looks at how modern biology is rewriting our understanding of genetics, disease and inheritance....

While plenty of entertaining books have been written about the history of alcohol and other intoxicants, none have offered a comprehensive, convincing answer to the basic question of why humans want to get high in the first place. Drunk elegantly cuts through the tangle of urban legends and anecdotal impressions that surround our notions of intoxication to provide the first rigorous, scientifically grounded explanation for our love of alcohol.

In November 1987, a young couple on an overnight trip to Seattle vanished without a trace. A week later, the bodies of Tanya Van Cuylenborg and her boyfriend Jay Cook were found in rural Washington. It was a brutal crime, and it was the perfect crime: With few clues and no witnesses, an international manhunt turned up empty, and the sensational case that shocked the Pacific Northwest gradually slipped from the headlines.

Are men literally born to cheat? Does monogamy actually serve women's interests? These are among the questions that have made The Moral Animal one of the most provocative science books in recent years. Wright unveils the genetic strategies behind everything from our sexual preferences to our office politics - as well as their implications for our moral codes and public policies.

Richard Dawkins, author of The God Delusion and a life-long committed Darwinist, abridges and reads this special audio version of Charles Darwin's famous book. A literally world-changing book, Darwin put forward the anti-religious and scientific idea that humans in fact evolved over millions of generations from animals, starting with fish, all the way up through the ranks to apes, then to our current form.