Showing results by publisher "----RM Alexander" in History & Commentary

A decade after World War II, there was still no such thing as open-heart surgery, and yet half a million Americans were dying from heart disease every year. After the first daring operation in 1954 and through the next three decades, five heroic surgeons braved the scorn of their peers, withstood fierce desperation, and faced possible death in order to devise procedures that would save overwhelming numbers of those doomed children and provide hope for a new life to all manner of heart-failing individuals.

The Immune Mystery follows doctor and researcher Anita Kåss' quest to solve the autoimmune puzzle, beginning with the premature death of her mother, who developed rheumatoid arthritis shortly after giving birth to Anita. As a child, Anita vowed to study the illness and one day find a cure. Becoming a respected doctor and researcher, Anita devoted herself to studying autoimmune disorders like rheumatoid arthritis, lupus, and multiple sclerosis. A compelling blend of incredible determination and cutting-edge science, this book changes the way we think about autoimmune diseases.

When the SARS virus broke out in China in January 2003, Karl Taro Greenfeld was the editor of Time Asia in Hong Kong, just a few miles from the epicenter of the outbreak. After vague, initial reports of terrified Chinese boiling vinegar to "purify" the air, Greenfeld and his staff soon found themselves immersed in the story of a lifetime. Deftly tracking a mysterious viral killer, China Syndrome takes listeners on a gripping ride that blows through the Chinese government's effort to cover up the disease and sounds a clarion call warning of a catastrophe to come.

Witness early, bloody, anaesthetic-free operations and first crude surgical instruments, trace the mapping of the circulatory system, follow the painstaking detective work that led to the decoding of the human genome and understand the role that potions, cures, therapies, herbal medicines and drugs have played in the human quest to tame and conquer disease, injury and death. An engrossing history and tale of drama and discovery that celebrates the milestones of medical history across generations and cultures.

As scientists confidently look forward to average life expectancies hitting 100+ years in some Western societies, it’s easy to forget how precarious our grasp on good health has been. It is a struggle no better demonstrated than by the myriad and extraordinary measures that humans have gone to – as diverse as animal sacrifice to stem cell transplants – in their quest to stave off death and disease. Acclaimed historian Mark Jackson takes a fresh global view of mankind’s great battle, exploring both Western and Eastern traditions.

Drawing on Crampton’s own experience of surviving a life-threatening disease only to find herself beset by almost constant anxiety about her health, A Body Made of Glass explores part of the landscape of illness that most memoirs don’t reach: the territory beyond survival or cure, where body and mind seem locked in a strange and exhausting kind of dance. The result is both a fascinating cultural history of hypochondria and a moving account of what it means to live with this invisible, elusive and increasingly widespread condition.

Beginning with the origins of the concept of mania—and the term maniac—in ancient Greek and Roman civilizations, renowned psychiatrist David Healy examines how concepts of mental afflictions evolved as scientific breakthroughs established connections between brain function and mental illness. Healy recounts the changing definitions of mania through the centuries, explores the effects of new terminology and growing public awareness of the disease on culture and society, and examines the rise of psychotropic treatments and pharmacological marketing over the past four decades.

In the late 1600s, a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth merchant, Antonie van Leeuwenhoek, look down their handmade microscopes. What they see introduces a radical concept that sweeps through biology and medicine, touching virtually every aspect of the two sciences and altering both forever. It is the fact that complex living organisms are assemblages of tiny self-contained, self-regulating units. Our organs, our physiology, our selves—hearts, blood, brains—are built from these compartments. Hooke christens them 'cells'.

Intensive care units and mechanical ventilation are the crucial foundation of modern medical care: without them, the appalling death toll of the COVID-19 pandemic would be even higher. In The Autumn Ghost, Dr. Hannah Wunsch traces the origins of these two innovations back to a polio epidemic in the autumn of 1952. Drawing together testimony from doctors, nurses, medical students, and patients, Wunsch relates a gripping tale of an epidemic that changed the world.

In the early 1960s, Dr. Frances Oldham Kelsey of the U.S. Food and Drug Administration became one of the most celebrated women in America when she prevented a deadly sedative from entering the U.S. market. A Canadian-born pharmacologist and physician, Kelsey saved countless Americans from the devastating side effects of thalidomide, routinely given to pregnant women to prevent morning sickness. As the FDA medical officer charged with reviewing Merrell Pharmaceutical’s application for approval, Kelsey was unconvinced that there was sufficient evidence of the drug’s efficacy and safety.

In Germany on Christmas Day 1956 a baby girl was born without ears. She was the first victim of the notorious thalidomide epidemic. There would be over 10,000 more across 46 countries. For years the world believed the United States had avoided the catastrophe. After Frances Kelsey at the FDA became suspicious of the dangers of thalidomide in 1960, she led a successful fight to block its commercial approval. But now, having probed government and corporate archives and interviewed hundreds of key players, Jennifer Vanderbes reveals a darker truth that lay buried for decades.

IQ scores have the power to determine the chances we have in life: the people we meet, the schools we attend, the jobs we get, the lives we live. Very few of us, however, understand what IQ tests and ratings really mean. In this fascinating, provocative book, Stephen Murdoch explains the turbulent history and controversial current uses of intelligence testing.

Notes on Nursing is a classic by Florence Nightingale (the first modern nurse). Florence Nightingale's methods were revolutionary in her time, and they form the basis for the techniques of patient management that have been taught ever since. Notes on Nursing is a great overview, in her own words, of Florence Nightingale's ideas on care, cleanliness, and the nursing process in general. Her directives are widely applicable today. First published in 1860, Notes on Nursing served as the cornerstone of the curriculum at the Nightingale School and other nursing schools established.

The cultural and medical history of dementia and Alzheimer's disease by a leading psychiatrist and bioethicist who urges us to turn our focus from cure to care.

Post-traumatic stress disorder was recognized as a psychiatric disorder in the latter part of the 19th century. In PTSD, Allan V. Horwitz traces the fluctuations in definitions of and responses to traumatic psychic conditions. Arguing that PTSD, perhaps more than any other diagnostic category, is a lens for showing major historical changes in conceptions of mental illness, he surveys the conditions most likely to produce traumas, the results of those traumas, and how to evaluate the claims of trauma victims.

This major new Radio 4 series charts the development of Western medicine and healing, from the ancient Greeks to the pioneering organ transplant operations of the 20th century and beyond.

Leading transplant surgeon Dr. Joshua Mezrich creates life from loss, moving organs from one body to another. In this intimate, profoundly moving work, he examines more than one hundred years of remarkable medical breakthroughs, connecting this fascinating history with the stories of his own patients. Gripping and evocative, How Death Becomes Life takes us inside the operating room and presents the stark dilemmas that transplant surgeons must face daily.

Part memoir, part illuminating treatise on why science is looking to the past for the future of medicine, Unlocking the Ancient Secrets to Healing chronicles the personal tribulations and professional discoveries behind the remarkable realization of Gail Lynn’s dream.

The Nobel laureate Otto Warburg was widely regarded in his day as one of the most important biochemists of the 20th century, a man whose research was integral to humanity’s understanding of cancer. He was also among the most despised figures in Nazi Germany. As a Jewish homosexual living openly with his male partner, Warburg represented all that the Third Reich abhorred. Yet Hitler and his top advisors dreaded cancer, and protected Warburg in the hope that he could cure it.

In the last half of the twentieth century, Don Thomas discovered a cure for every marrow-based disease—like leukemia, lymphoma, and sickle-cell anemia—forever changing treatment for some of the deadliest illnesses. His feats were extraordinary, earning him a Nobel Prize, and the cascade of treatments he inspired have reshaped and will continue to reshape the practice of clinical medicine. Yet no one has ever written Thomas’s courageous story.Dr. Frederick R. Appelbaum, a member of Thomas’s research team, does so for the first time.