• Magnus Unemo on Zoliflodacin treatment for gonorrhea
    Feb 5 2026

    Elisa Pucu from The Lancet Microbe interviews Dr. Magnus Unemo of Örebro University about the clinical implications and key findings from his research. They discuss about the the microbiological analysis and whole genome sequencing of treatment failures from the zoliflodacin phase 3 clinical trial for gonorrhea—revealing insights that could change the future of treatment and antibiotic resistance.

    Click here to read the full articles: https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(25)00198-3/fulltext

    https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01953-1/fulltext

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    16 mins
  • Amber Barton on mass drug administration to eradicate yaws in Papua New Guinea
    Jan 6 2026

    Phoebe Ashley-Norman of The Lancet Microbe speaks to Amber Barton about the neglected tropical disease, yaws. Efforts to eradicate yaws were first made in the 1950s through a WHO and UNICEF campaign that reduced yaws prevalence by 90%, but it remained endemic in some regions.

    Global efforts involving the mass drug administration of azithromycin continue in pursuit of the WHO 2030 yaws eradication goal. In this podcast, Amber discusses how genomic epidemiology can be used to investigate the effectiveness of yaws eradication strategies, detect sublineages of yaws at higher resolution, and improve our understanding of macrolide resistance.

    Click here to read the full article: https://www.thelancet.com/journals/lanmic/article/piiS2666-5247(25)00157-0/fulltext

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    22 mins
  • Britt Koskella on bacteriophages as a signature of microbiome health
    Dec 22 2025

    Elena Dalla Vecchia of The Lancet Microbe speaks to Dr Britt Koskella about bacteriophages and phageome, their role in modulating the bacteriome, their potential use as signatures of microbiome health and dysbiosis, and hence, indirectly, as markers of host health and disease status.

    From an ecological perspective, parasites (such as bacteriophages) are key drivers of the evolution of their hosts (bacteria), and so one might expect to find diverse and rich bacteriomes in the presence of a highly diverse and thriving microbiome: Britt has been exploring this possibility and discusses it in this episode.

    Click here to read the full article: https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(25)00124-7/fulltext

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    28 mins
  • Christian Malaka and Livia Patrono on the surveillance of mpox in the Central African Republic
    Nov 3 2025

    Rebecca Barksby of The Lancet Microbe speaks to Dr Christian Malaka and Dr Livia Patrono on mpox in the Central African Republic and how researchers are using genomic surveillance to provide insights into the epidemiology of the virus.

    Read the full article: https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(25)00101-6/fulltext

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    34 mins
  • Sam Lipworth and Nicole Stoesser on genotypic and phenotypic antimicrobial resistance in Escherichia coli
    Oct 7 2025

    Elena Dalla Vecchia talks with Dr Sam Lipworth and Prof Nicole Stoesser about the challenges and variability in genotypic predictions of antimicrobial resistance in Escherichia coli, about which they have published two papers in The Lancet Microbe: “Exploring uncatalogued genetic variation in antimicrobial resistance gene families in Escherichia coli: an observational analysis” and “Estimating the association of antimicrobial resistance genes with minimum inhibitory concentration in Escherichia coli, an observational study”.

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    26 mins
  • Anastasia Theodosiou on controlled human infection with Neisseria lactamica in pregnancy
    Apr 1 2025

    Rebecca Barksby of The Lancet Microbe speaks to Dr Anastasia Theodosiou about performing a controlled human infection study in pregnant women investigating mother-to-infant transmission of Neisseria lactamica.

    Read the full article:

    https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(24)00254-4/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanmic

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    30 mins
  • Susan Meiring, Vanessa Quan, and Nelesh Govender on bloodstream infections in neonates in South Africa
    Feb 25 2025

    Elena Dalla Vecchia of The Lancet Microbe speaks to Susan Meiring, Vanessa Quan, and Nelesh Govender about bloodstream infections in neonates at lower-tier South African hospitals.

    Read the full paper, Pathogen aetiology and risk factors for death among neonates with bloodstream infections at lower-tier South African hospitals: a cross-sectional study, at https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(24)00257-X/fulltext

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    26 mins
  • Laurence Armand-Lefevre and Luc Samison on surveillance of antimicrobial resistant Escherichia coli in humans, chickens, and the environment in Madagascar
    Aug 5 2024

    Rebecca Barksby of The Lancet Microbe speaks to Professor Laurence Armand-Lefevre and Professor Luc Hervé Samison about implementing the WHO Tricycle Protocol in Madagascar for the surveillance of extended-spectrum β-lactamase producing Escherichia coli in humans, chickens, and the environment.

    Read the full article:
    https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(24)00228-1/fulltext?dgcid=buzzsprout_icw_podcast_generic_eclinm

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    27 mins