Dr. Stacey Clardy talks with Casey R. Vanderlip about whether the accelerated decline in episodic memory among APOE4 carriers is due to increased Aβ deposition or heightened susceptibility to Aβ-related effects.

Read the related article in Neurology®.

Disclosures can be found at Neurology.org.

Dr. Halley Alexander talks with Dr. Juan Luis Alcala-Zermeno about the outcomes of epilepsy surgery, specifically for patients with tonic-clonic seizures.

Read the related article in Epilepsia.

Read the additional related article in Epilepsia.

Listen to the previous podcast episode mentioned in this episode.

Disclosures can be found at Neurology.org.

The August 2025 recall spotlights four previously released episodes on topics related to dementia diagnosis. The episode begins with Dr. Amy Brodtmann discussing the complexities of diagnosing frontotemporal dementia in clinical practice. Next, Dr. Joseph Therriault delves into the use of plasma biomarkers in diagnosing Alzheimer disease. In the third episode, Dr. Trey Bateman discusses the growing significance of blood-based biomarkers in Alzheimer disease. The episode concludes with Dr. Gregg Day discussing the clinical implications of using plasma biomarkers in real-world patient care.

Podcast links:

Frontotemporal Dementia Differential Diagnosis in Clinical Practice

Diagnosis of Alzheimer Disease Using Plasma Biomarkers

Understanding Blood-Based Biomarkers in Alzheimer Disease

Diagnostic Performance of Plasma Biomarkers in the Outpatient Memory Clinic

Article links:

Frontotemporal Dementia Differential Diagnosis in Clinical Practice

Diagnosis of Alzheimer’s Disease Using Plasma Biomarkers Adjusted to Clinical Probability

Diagnostic Performance of Plasma p-tau217 and Aβ42/40 Biomarkers in the Outpatient Memory Clinic

Disclosures can be found at Neurology.org.

Dr. Kathryn Krulisky talks with Dr. Jordan Garris about educational gaps in understanding FND, the impact of stigma on patient care, and the importance of empathy in medical training.

Read the related article in Neurology® Education.

Disclosures can be found at Neurology.org.

Dr. Shuvro Roy talks with Dr. Daniel Blockmans about the efficacy and safety of upadacitinib as a treatment option for giant-cell arteritis.

Read the related article in The New England Journal of Medicine.

Disclosures can be found at Neurology.org.

Dr. Jason Crowell talks with Dr. Daniel Weintraub about clinical considerations and strategies for effective communication when addressing cognitive concerns in patients with Parkinson disease.

Read the related article in Neurology®.

Listen to the related podcast episode with Dr. Jeff Ratliff.

Disclosures can be found at Neurology.org.

Dr. Dan Ackerman talks with Dr. James Ernest Siegler about the complexities of treating ESUS and emphasizes the importance of personalized treatment approaches based on individual patient factors.

Read the related article in Neurology®.

Disclosures can be found at Neurology.org.

Dr. Trey Bateman talks with Dr. Gregg Day about the study design, findings, and clinical implications of using plasma biomarkers in real-world patient care.

Read the related article in Alzheimer's & Dementia.

Disclosures can be found at Neurology.org.