Steve A. Webb, MBBS, MPH, PhD, professor, Royal Perth Hospital, The University of Western Australia discusses Platform Clinical Trials for the Efficient Evaluation of Multiple Treatments with JAMA Statistical Editor Roger J. Lewis, MD, PhD.

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• How to Use and Interpret the Results of a Platform Trial

Kendra D. Sims, PhD, postdoctoral associate in Epidemiology, Boston University, discusses Tipping Point Analysis: Assessing the Potential Impact of Missing Data with JAMA Statistical Editor Roger J. Lewis, MD, PhD.

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Edward C. Norton, PhD, University of Michigan Health Management and Policy, discusses Instrumental Variables and Heterogeneous Treatment Effects with JAMA Statistical Editor Roger J. Lewis, MD, PhD.

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Jody D. Ciolino, PhD, Northwestern University, Feinberg School of Medicine discusses Factorial Clinical Trial Designs with JAMA Statistical Editor Roger J. Lewis, MD, PhD

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Maria Mori Brooks, PhD, University of Pittsburgh School of Public Health, discusses "Assessing Unexpected Circumstances That Lead to Modifications in Clinical Trial Design, Conduct, or Analysis" in the JAMA Guide to Statistics and Methods series, with JAMA Statistical Editor Roger J. Lewis, MD, PhD.

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• Assessing Unexpected Circumstances That Lead to Modifications in Clinical Trial Design, Conduct, or Analysis

Lars W. Andersen, MD, MPH, PhD, DMSc, Aarhus University, discusses collider bias in the JAMA Guide to Statistics and Methods series with JAMA Statistical Editor Roger J. Lewis, MD, PhD.

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John M. Lachin, ScD, Biostatistics Center, George Washington University, discusses Nonparametric Statistical Analysis with JAMA Statistical Editor Roger J. Lewis, MD, PhD.

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Andrew D. Althouse, PhD, University of Pittsburgh School of Medicine discusses The Use of Historical Controls in Clinical Trials with JAMA Statistical Editor Roger J. Lewis, MD, PhD.

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