Kenneth McCurry, MD, and Marie Budev, DO, share Cleveland Clinic’s multidisciplinary approach to managing end-stage lung disease and advancing lung transplantation. They discuss innovations such as ex vivo lung perfusion (EVLP), ECMO bridging, and strategies for expanding donor and recipient criteria, including complex and multi-organ cases. The episode also highlights ongoing research and clinical trials aimed at improving post-transplant outcomes and reducing chronic rejection.

Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Samir Kapadia, MD, Chairman of Cardiovascular Medicine at Cleveland Clinic, and David Zidar, MD, PhD, an interventional cardiologist and immunologist, introduce Cleveland Clinic’s Cardioimmunology Center, a new initiative focused on the intersection of immune pathways and cardiovascular disease. They discuss how immune system activity can influence heart health and discuss innovative approaches to identifying and managing cardiovascular risk through immunologic biomarkers.

Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Lee Kirksey, MD, Aravinda Nanjundappa, MBBS, MD, and G. Jay Bishop, MD, discuss a multidisciplinary approach to peripheral artery disease (PAD) management. They explore evidence-based strategies including early detection, optimal medical therapy, supervised exercise programs and advanced endovascular and surgical interventions, emphasizing team-based care and longitudinal follow-up for improved outcomes.

Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469

Allan Klein, MD, and Tom Kai Ming Wang, MBChB, discuss the 2025 ACC Concise Clinical Guidance on pericardial disease. They explore updated diagnostic criteria, the role of multimodality imaging and a shift toward IL-1 blockers for recurrent pericarditis. Learn practical strategies to optimize patient outcomes and avoid misdiagnosis or undertreatment, along with insights on surgical options and emerging clinical trials.

Read about the new guidance. https://consultqd.clevelandclinic.org/resource-for-avoiding-misdiagnosis-and-undertreatment-in-pericarditis

Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469

Lars Svensson, MD, PhD, and Xiaoying Lou, MD, share a deep dive into valve-sparing aortic root surgery, an advanced technique that preserves the patient’s native valve while treating aortic aneurysms.

Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Steven Nissen, MD, and Luke Laffin, MD, discuss a groundbreaking phase 1 trial of a CRISPR-Cas9 gene-editing therapy targeting ANGPTL3. They explore its potential as a one-time treatment to significantly lower LDL cholesterol and triglycerides, with promising safety and efficacy data that could reshape lipid management.

Learn more about C5 Research at Cleveland Clinic.
https://my.clevelandclinic.org/research/c5research

Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

A. Marc Gillinov, MD, and Tarek Malas, MD, discuss the long-term benefits of mitral valve repair for patients with degenerative mitral valve disease. They explore surgical decision-making, robotic techniques and post-operative recovery strategies like cardiac rehab that support lifelong valve function and optimal patient outcomes.

Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.

Kenneth McCurry, MD, and Marie M. Budev, DO, discuss Cleveland Clinic’s leadership in lung and multi-organ transplantation, highlighting innovations like ex vivo lung perfusion (EVLP) and the collaborative care model that supports complex transplant cases. They also acknowledge Lung Transplant Awareness Day, a national initiative aimed at increasing education about end-stage lung disease.

Looking to refer a patient? Please reach out to our Physician Referral team Mon. - Fri., 8 a.m. - 5 p.m. (ET) at 855.751.2469.