London 1950. Peggy Ronoscki is happily settling into life running her guesthouse on Mulberry Lane, surrounded by close friends and family. Life just seems too good...but then disaster strikes. Pip, her beloved son, is left in a coma following a devastating car crash, and a young girl collapses in the market, leaving Peggy no option but to nurse her back to health. As things begin to go awry, Peggy worries she has brought trouble to her doorstep Can her life ever return to normal? Or has Peggy’s good nature led her astray?

Liverpool, 1939. Bella Rogers thought her life was just starting; she can’t wait to get married to her childhood sweetheart, Bobby. But when war is declared and Bobby is called up, his letters stop, leaving Bella heartbroken and alone. Then her family is torn apart by tragedy when her angelic 5-year-old sister dies from a terrible illness. They can barely afford a funeral, but the church is packed with the entire community, devastated for their loss. Grieving for her sister and lost love, Bella finds a job at the Bryant and May factory, making matches.

Oxford Street, London 1915. Sally Harper quietly battles to keep Harpers afloat in the difficult days of the war, whilst husband Ben is working all hours for the War Office. Beth Burrow is fighting concern for her husband, Jack, now at sea with the Merchant Navy, and the fear she may never see him again and be blessed with a child. Driven to exhaustion, Maggie Gibbs, is now working as a nursing assistant on the battlefields in France. With the everyday horrors of the casualties of war to contend with she suffers her own personal tragedy when her fiancé's plane ditches in the sea.

England, 1943: Home is no longer safe for eight-year-old twins Molly and Jacob. Night after night, wailing bombs and screeching planes skim the rooftops overhead. They cradle each other, shivering in terror, not knowing if they'll live to see dawn. Their mother, Martha, has no choice but to evacuate them to the safety of the countryside. At the train station, Martha bites back tears as she says good-bye to her precious children. Knowing she might never see them again, she gives Jacob a letter, pressing the envelope into his hands and telling him to only read it if they are in danger.

Bristol, 1939. School leaver Maisie Miles suspects her father, a small-time crook, has an ulterior motive for insisting she gets a job at the W. D. & H. O. Wills tobacco factory but keeps it to herself. She's befriended by effervescent Phyllis Mason and kind-hearted Bridget Milligan who take pity on her and take Maisie under their wing. But beneath their happy-go-lucky exteriors, they all harbour dreams and worries about what the future holds. 

Liverpool, 1945. As the war draws to a close, Alice and Terry Lomax are building a new life with their young daughter Cathy. After years away fighting, Terry is a stranger to his daughter and must work hard to win her trust and love. Alice and old friend Sadie work in the haberdashery of Lewis’s department store, where bomb damage scars the walls and rationing is still in force. Though memories of those lost in the war are fresh, Alice and Sadie look forward to the future. 

1940, Liverpool: Alice Turner and her best friend, Millie Markham, work for the war effort at Rootes munitions factory, making shell caps and Halifax bombers. Alice’s sweetheart, Terry, is home from the front for a brief period of leave. But the honeymoon is soon over. Terry must go back to the dangers of Nazi-occupied France, and the ever-present air raid sirens quickly bring Alice back down to earth. 

It is 1939, and working-class Evie Bishop has received a scholarship to study mathematics at Oxford when tragedy turns her life upside down. Evie must seek a new future for herself and, inspired to contribute to the war effort, joins the Women’s Auxiliary Air Force as an Ops Room plotter. Posted to a fighter station on the Sussex Coast, Evie befriends two other WAAFs. But the German bombers seem to know more than they should about the base’s operations, and soon Evie, May and Jess are caught up in a world more dangerous than they ever imagined. 

1949. Peggy and Able Ronoscki's seaside cafe in Devon is thriving, and their twins, Fay and Freddie, are growing up fast. To pursue her daughter’s destiny, Fay must train in London and Peggy is faced with a dilemma of moving the family back to London once more. Meanwhile, Peggy’s elder daughter, Janet, has her own troubles. She fears her husband is having an affair and is desperately unhappy. Peggy is torn two ways and can only hope that a reunion with her friends at Christmas can help resolve her problems. 

It is two years since Harpers opened in Oxford Street and Ben is planning to expand the premises. Life is good for Sally and Ben as they look forward to their first child and hope for a prosperous future. Beth is settling into married life with Jack, gradually recovering from her aunt’s tragic death, though still unable to conceive a child. New girls have joined Harpers and Marion, Janice and Becky all become a part of the daily life at the busy store. Rachel is undecided whether to marry a man she isn’t sure she can trust, while Minnie meets an old love.

England, 1937: After a devastating childhood at Blakely Hall Orphanage, 15-year-old Sandra is released. She finds work as a housemaid, finally able to put her past behind her. But the start of World War Two throws the country into turmoil, and her brother, Alf, is sent away to fight, leaving her completely alone. Germany, 1939: Eleven-year-old Frieda is about to board a ship bound for England with her brother, Kurt. But at the last moment, as Frieda stands on the deck crammed with frightened children, she spots her brother jumping off, back to land.

Lara Perryman has spent her whole life travelling for her busy corporate job, so it's a relief when she takes early retirement and settles in a leisure village in Wiltshire. She quickly makes friends with the other residents and finds herself entangled in the ups and downs, triumphs and tragedies of her new community. 

After a health scare, 77-year-old Barbara goes to convalesce in the sleepy Somerset village of Winsleigh Green with her sister, Pauline, who is now a widow. The sisters are like chalk and cheese - Barbara, outspoken and aloof and Pauline, good natured and homely - so it’s not long before the tension starts to rise. But when Pauline accidentally knocks down a vagrant who goes by the name of Bisto Mulligan, the ladies find themselves with another houseguest.

Lillian is distraught - she must register for compulsory war work. Emily is also furious - her dream job as a chef will have to be put on hold, whilst Alice must abandon her plans of college. Staring at an identical letter, Elsie feels a kindling of hope, and down in London Agnes is packing her bags with a smile. Sharing grief and joy, lost dreams and gained opportunities, the five new bomb girls will find friendship and strength that they never before thought possible.

Belinda Layton is a surplus girl. One of the many women whose dreams of marriage perished in the Great War, with the death of her beloved fiancé, Ben. After four years of mourning, she finally feels ready to face whatever her future holds without him. But Ben's family can't countenance her putting him to rest, while all her own family care about is getting hold of her meagre factory wages. When Belinda joins a secretarial class to try to better herself, little does she imagine that it will open up a whole new world to her.