The Philadelphia Chromosome cover art

The Philadelphia Chromosome

A Mutant Gene and the Quest to Cure Cancer at the Genetic Level

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The Philadelphia Chromosome

By: Jessica Wapner
Narrated by: Heather Henderson
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About this listen

Almost daily, headlines announce newly discovered links between cancers and their genetic causes. Science journalist Jessica Wapner vividly relates the backstory behind those headlines, reconstructing the crucial breakthroughs, explaining the science behind them, and giving due to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 50,000 people diagnosed each year with chronic myeloid leukemia (CML). It is an astonishing tale that will provide victims of other cancers and their loved ones realistic hope that cures may yet be found in their lifetimes.

The Philadelphia Chromosome charts the milestones that led to present-day cancer treatment and tells the inspiring story of the dedicated men and women who, working individually and in concert, have sought to plum the mysteries of the human genome in order to conquer those deadly and most feared diseases called cancer.

©2013 Jessica Wapner (P)2013 HighBridge Company.
Biological Sciences Cancer Evolution & Genetics Genetics History History & Commentary History & Philosophy Medicine & Health Care Industry Pharmacology Physical Illness & Disease Science Genetic disease Medicine

Critic Reviews

“[Wapner’s] gracefully written history skillfully combines both the science and humanity of this fascinating search for a cure for chronic myeloid leukemia.” ( Publishers Weekly)
“The story of the Philadelphia chromosome is truly the story of modern cancer biology. . . . Jessica Wapner stitches the whole story together with tenacity, diligence (and humor). This is a wonderful, readable, and highly informative book.” (Siddhartha Mukherjee, Pulitzer Prize-winning author of The Emperor of all Maladies)
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