From the creator of the wildly popular blog Wait but Why, a fun and fascinating deep dive into what the hell is going on in our strange, unprecedented modern times.

Three of the most important words in science are I don't know. Not knowing implies a universe of opportunities—the possibility of discovery and surprise. Our understanding of science has advanced immeasurably over the last 500 years, yet many fundamental mysteries of existence persist: How did our universe begin? How big is the universe? Is time travel possible? What’s at the center of a black hole? How did life on Earth arise? Are we alone? What is consciousness, and can we create it?

Derek Parfit (1942–2017) is the most famous philosopher most people have never heard of. Widely regarded as one of the greatest moral thinkers of the past hundred years, Parfit was anything but a public intellectual. Yet his ideas have shaped the way philosophers think about things that affect us all: equality, altruism, what we owe to future generations, and even what it means to be a person. In Parfit, David Edmonds presents the first biography of an intriguing, obsessive, and eccentric genius.

You are about to hear several more stories in this volume that are shocking and disturbing, but they’re also true. These things really do happen in the world. The stories paint a picture of human depravity that many would prefer to remain hidden. However, it is only by dragging evil into the light that we can begin to understand its terrible allure.

Social psychologist and Professor at the Stanford Graduate School of Business Brian Lowery argues for the radical idea that the “self” as we know it, does not exist. The self—that “voice in your head”—is a social construct, created in our relationships and social interactions. We are unique because our individual pattern of relationships is unique. We change because our relationships change. Your self isn’t just you, it’s all around you.

There is a war on for your mind. We are endlessly confronted by those who would manipulate us – advertisers, pick-up artists, politicians, big tech, cult leaders and many more – even the humble waiter who asks, ‘Still or sparkling?’ All forms of communication are designed to persuade you in some way. Politicians and nudge units manipulate us into agreeing with controversial policies. Adverts tell us to buy lots of this, but none of that. The news tells us what to care about. Charities compete for our support. Social media buffets us with algorithms.

Conjectures and Refutations is one of Karl Popper’s most wide-ranging and popular works, notable not only for its acute insights into the way scientific knowledge grows, but also for applying those insights to politics and to history. It provides one of the clearest and most accessible statements of the fundamental idea that guided his work: not only our knowledge but our aims and our standards grow through an unending process of trial and error.

Jay Garfield, a leading expert on Buddhist philosophy, offers a brief and radically clear account of an idea that at first might seem frightening but that promises to liberate us and improve our lives, our relationships, and the world. Drawing on Indian and East Asian Buddhism, Daoism, Western philosophy, and cognitive neuroscience, Garfield shows why it is perfectly natural to think you have a self—and why it actually makes no sense at all and is even dangerous. Most importantly, he explains why shedding the illusion that you have a self can make you a better person.

From Stoics to existentialists, in philosophy and literature, discussion of the philosophy of life—of love and death, of courage, fortitude and wisdom—challenges us all to think about what kinds of life are truly worth living. In this summation of a lifetime thinking and writing about this great question, A. C. Grayling explores with clarity and depth the ideas that each of us must use in answering it for ourselves.

Medicine has become inhuman, to disastrous effect. The doctor-patient relationship - the heart of medicine - is broken: doctors are too distracted and overwhelmed to truly connect with their patients, and medical errors and misdiagnoses abound. In Deep Medicine, leading physician Eric Topol reveals how artificial intelligence can help. AI has the potential to transform everything doctors do, from notetaking and medical scans to diagnosis and treatment, greatly cutting down the cost of medicine and reducing human mortality.