In 1820, Salem Street is sparkling and new: eight small terraced houses built by a Lancashire mill owner for his best workers. Annie Gibson's family is one of the first to move in - a step up in the world for them. But when her mother dies, Annie's happy childhood ends and she is left to bring up her brother and sister. Red-haired, intelligent and startlingly pretty, Annie soon finds herself banished from home by a jealous stepmother. She finds work in the local doctor's household, where she learns about the fascinating world outside Salem Street.

Lancashire, 1930: Leah Turner's father has been killed in an accident at the laundry, and since her mother died years ago it falls to her to become sole provider for her little sister. But women's wages are half those of men, and pawning the few belongings she has left will keep their vicious rent collector at bay for only a few weeks, so even if she finds a job, they'll lose their home. Out of the blue, Charlie Willcox, the local pawnbroker, offers her a deal.

Lancashire, 1895. When her controlling stepfather suddenly dies, it seems that Elinor Pendleton finally has a chance of freedom. But her hopes are soon dashed when she learns that the thuggish Jason Stafford has inherited every penny, and is determined to have Elinor too. Forced to flee with her maid, Maude, Elinor finds shelter with Maude's distant cousin in the remote village on the shore of Jubilee Lake. But Walter Crossley has troubles of his own. Having lost his closest family in a tragic accident, he needs one of his grandsons to return from America to inherit his farm.

Jo Melling has arrived in Birch End from Australia, still grieving her father's recent death. She's not intending to stay long, but after tracking down her distant family, Jo becomes more involved in village life than she could ever have imagined - and suddenly in danger too. Jo also finds herself drawn to Nick, a handsome newcomer to the village. Nick had planned to settle in Birch End and start a business, but as he grows closer to Jo, he realises he may have to choose between his dreams and a chance at love. 

Emmy Carter's mother is a prostitute - and her life has made Emmy determined to avoid the same fate. But Emmy is beautiful, so attracts unwanted attention; her mother's protector has his eye on her, as does evil Marcus Armistead, her employer's nephew. Marcus is excited by Emmy's virginity and has her kidnapped, but Emmy hits him over the head and escapes. Marcus, further enraged, kills her mother and becomes even more determined to rape Emmy, but the combined efforts of the local parson and Emmy's young suitor manage to keep her safe from harm. 

Keara Michaels doesn't want to leave her family in Ireland, but fate sends her first to Lancashire, then across the sea to Australia, pregnant and penniless. And Theo Mullane, the man who loves her, is married, with an ailing baby son, so cannot follow her as he longs to. Mark Gibson leaves Lancashire to avoid marriage. But gold prospecting is a dangerous pursuit, and when his gentle young wife dies in childbirth, his father-in-law kidnaps the baby. So Mark runs away again, this time to Western Australia, where he employs Keara in his country inn.

Cassandra Blake has raised her three motherless sisters. The girls are the pride of their book-loving, impractical father, and not in a hurry to marry. Then the American Civil War cuts off supplies of cotton to Lancashire, the mills fall silent and there is no work. There is a stark choice: stay and risk starvation or pack up and begin again elsewhere. Cassandra has fallen in love with Reece Gregory, but he can't support a wife. When he's given the chance to start a new life in Western Australia, he seizes the opportunity, promising to send for her.

Janey is 18 and living in a small flat with her baby daughter. Just as her new life starts to show promise, her past catches up with her. Nicole is renting one of the new luxury flats. She’s just walked away from her husband and teenage sons, tired of being treated as a servant, suspecting her husband of having an affair. Winifred has lived in her large family home for over 80 years but it’s all getting too much, though she doesn’t want to leave. Things are not what they seem, and danger can strike both rich and poor.

Seventeen-year-old Liza is happy working as a lady's maid - until her employers decide to emigrate and her father makes up his mind that she is to wed an older widower whom she detests. Determined to avoid a loveless marriage, Liza plans to run away. But when the widower rapes her to force her to marry him, she flees back to the family for whom she worked. She feels she has no choice but to go with them to Australia, and they all set out on the long voyage. On board ship, Liza discovers to her horror that she has fallen pregnant. 

In a village in Wiltshire, just off a busy road, Larch Tree Lane winds slowly up a low hill. Among the residents is Maggie Hatherall, full of life despite her advancing years, who worries what she is going to do with her 200-year-old home. Lucia Grey has escaped a bad marriage but her ex is reluctant to let her start a new life free of him. And for architect Corin Drayton, an unexpected inheritance is the start of a complicated family wrangle. From the cottages and farms to the local shop, pub and old manor house, the residents' lives are set to intertwine and relationships bloom.

Carrie Preston is used to hard work - oldest of 10, with an incompetent mother and a drunken father, she struggles to find food for her siblings. But nothing could have prepared her for the day fate deals her family the cruellest of hands, rendering them more desperate than ever. In a harsh world, small acts of kindness can bring great hope - Eli Beckett's offer of a job at the Dragon pub promises a better future for Carrie, especially as Eli's uncle has offered his nephew some spare land to build a music room.

Bristol 1936. Jenny Crawford has resigned herself to a loveless marriage living hand to mouth with their two children. Like many others, husband Roy struggles to find work at the docks but a chance encounter turns the family's fortunes around. Not only does he get regular work but they are also allocated a council house on Coronation Close on the outskirts of the city. Jenny and the children are overjoyed, this is the fresh start she could only ever dream of. But trouble feels never too far away.

Jessie Burton is lively and intelligent - she wants more than the respectable life in service her mother has planned for her. Times are changing; railways are being built across the land, bringing new freedom and possibilities. Jessie tastes that freedom when she meets an ambitious young navvy, newly arrived in Yorkshire. The attraction between them is overwhelming. And Jared Wilde is determined to make Jessie his wife. 

When Emily Mattison falls victim to a near-fatal accident shortly after receiving an unexpected inheritance from a distant cousin, her ruthless nephew George seizes the opportunity to take control of his aunt's assets. It's only when Emily reaches The Drover's Hope, the former pub on the edge of the Lancashire moors bequeathed to her by her late cousin Penelope, that she begins to feel safe. She also discovers that love can be found in the most unexpected places. But it's not so easy to escape the clutches of someone as determined as George.

Singapore in the 1860s is exotic and yet terrifying for a penniless Englishwoman, alone and vulnerable after her mother's death. Too pretty to obtain a governess' job, Isabella Saunders accepts an offer from Singapore merchant Mr Lee to teach him English and live with his family. Two years later Bram Deagan arrives in Singapore, determined to make his fortune as a trader. Mr Lee sees a way to expand his business connections and persuades Isabella to marry Bram. Bravely, she sets sail for a new land and life.