When DC crime scene analyst Dr. Ellie Carr is called to investigate the heartrending case of a missing baby, she's shocked to discover that the child's mother is her own cousin. Close during their impoverished childhoods, Ellie and Rebecca eventually drifted apart. Rebecca is now half of a Washington power couple, and she and her wealthy lobbyist husband, Hunter, have been living a charmed life in an opulent mansion—until their infant son is taken. At first antagonists, then allies, Ellie and Rachael race to find the baby alive and bring the kidnappers to justice.

In the quiet town of Painters Mill, an Amish family of seven has been found brutally murdered on their farm. Chief of Police Kate Burkholder and her small force have few clues, no motive, and no suspect. Formerly Amish herself, Kate is no stranger to secrets, but she can't get her mind around the senseless brutality of the crime. State agent John Tomasseti arrives on the scene to assist. He and Kate worked together on a previous case during which they began a tentative relationship, but each is wary of commitment. The disturbing details of this case will push them to their limits.

Everyone in the small town of Denton is searching for Isabelle Coleman, a missing 17-year-old girl. All they've found so far is her phone and another girl they didn't even know was missing. Mute and completely unresponsive to the world around her, it's clear this mysterious girl has been damaged beyond repair. All Detective Josie Quinn can get from her is a name: Ramona. Currently suspended from the force for misconduct, Josie takes matters into her own hands as the name leads her to evidence linking the two girls.

An eight-year-old girl, Chelsea Compton, is missing in Pine Valley, California, and for Detective Katie Scott it’s a cruel reminder of the friend who disappeared from summer camp 20 years ago. Unable to shake the memories, Katie vows she won’t rest until she discovers what happened to Chelsea. But as Katie starts to investigate, the case reveals itself to be much bigger and more shocking than she feared. Hidden deep in the forest she unearths a makeshift cemetery: a row of graves, each with a brightly colored teddy bear.

FBI Agent Ava James had a difficult entrance into the FBI. After shadowing famed agent Emma Griffin inside the disturbing underbelly of Windsor Island, Ava James is now ready to carve out her own path in the agency.

When Penny Matthews, a seven-year-old girl with blonde curls and a gap-toothed smile, goes missing in the Appalachian mountains, Detective Ellie Reeves is called straight to the scene. According to Penny’s parents, their daughter vanished after a picnic by the creek. All that’s left behind is a pink friendship bracelet etched with “Penny”.

Four bodies have been discovered along Europe’s riverbanks, placed with care—and completely drained of blood. Pinpricks on their throats indicate a slender murder weapon, but DNA found in the wounds suggests something far more sinister. Tasked with investigating, the FBI recruits Agents Della Hamilton and Mason Carter to Blackbird, an international offshoot of the Krewe of Hunters. If you want to catch a vampire killer, you need agents who can speak with the dead.

In 1919, Delano, Georgia, appoints its first chief of police. Honest and hardworking, the new chief is puzzled when young men start to disappear. But his investigation is ended by the fatal blast from a shotgun. Delano's second chief-of-police is no hero, yet he is also disturbed by what he sees in the missing-persons bulletins. In 1969, when Delano's third chief takes over, the unsolved disappearances still haunt the police files.

Detective Kara Quinn, on leave from the LAPD, is on an early morning jog in her hometown of Liberty Lake when she comes upon the body of a young nurse. The manner of death shows a pattern of highly controlled rage. Meanwhile in DC, FBI Special Agent Mathias Costa is staffing his newly minted Mobile Response Team. Word reaches Matt that the Liberty Lake murder fits the profile of the compulsive Triple Killer. It will be the first case for the MRT. This time, they have a chance to stop this zealous, if elusive, killer before he strikes again.

Twenty years ago Emily Mills's father was murdered, and she found his body hanging in the backyard. Her younger sister, Madison, claims she was asleep in her room. Her older sister, Tara, claims she was out with friends. The tragedy drove their mother to suicide and Tara to leave town forever. The killer was caught. The case closed. Ever since, Emily and Madison have tried to forget what happened that night - until an eerily similar murder brings it all back.