Biological Age

Oxygen takes the listener on an enthralling journey, as gripping as a thriller, as it unravels the unexpected ways in which oxygen spurred the evolution of life and death.

For decades, the medical community has looked to a variety of reasons for why we age, and the consensus is that no-one dies of old age; they die of age-related diseases. That's because ageing is not a disease - it is inevitable. But what if everything you think you know about ageing is wrong? What if ageing is a disease? And that disease is curable. In Lifespan, Dr David Sinclair, one of the world’s foremost authorities on genetics and ageing, argues just that.

Professor Rose Anne Kenny has 35 years of experience at the forefront of ageing medicine. In Age Proof, she draws on her own pioneering research and the latest evidence to demystify why we age and shows us that 80% of our ageing biology is within our control: we can not only live longer lives but become happier and healthier deep into our later years.

Revealed for the first time in Racing for the Bomb, Groves played a crucial and decisive role in the planning, timing, and targeting of the Hiroshima and Nagasaki missions. Norris offers new insights into the complex and controversial questions surrounding the decision to drop the bomb in Japan and Groves' actions during World War II, which had a lasting imprint on the nuclear age and the Cold War that followed.

Working with thousands of patients, Dr. Gundry has discovered that the “diseases of aging” we most fear are not simply a function of age; rather, they are a byproduct of the way we have lived over the decades. In The Longevity Paradox, he maps out a new approach to aging well - one that is based on supporting the health of the “oldest” parts of us: the microorganisms that live within our bodies.

The fascinating group of animals called dinosaurs became extinct some 65 million years ago (except for their feathered descendants). In their place evolved an enormous variety of land creatures, especially mammals, which in their way were every bit as remarkable as their Mesozoic cousins. The Age of Mammals, the Cenozoic Era, has never had its Jurassic Park, but it was an amazing time in earth's history, populated by a wonderful assortment of bizarre animals. The rapid evolution of thousands of species of mammals brought forth many incredible creatures—including our own ancestors.

All of us would like to live longer, or to slow the debilitating effects of age. In How We Age, Coleen Murphy shows how recent research on longevity and aging may be bringing us closer to this goal. Murphy, a leading scholar of aging, explains that the study of model systems, particularly simple invertebrate animals, combined with breakthroughs in genomic methods, have allowed scientists to probe the molecular mechanisms of longevity and aging.

Life is the most extraordinary phenomenon in the known universe; but how does it work? Even in this age of cloning and synthetic biology, the remarkable truth remains: nobody has ever made anything living entirely out of dead material. Life remains the only way to make life. Are we missing a vital ingredient in its creation? Like Richard Dawkins' The Selfish Gene, which provided a new perspective on how evolution works, Life on the Edge alters our understanding of life's dynamics.

When Mail journalist Sandra Parsons suffered a serious back injury in her mid-40s, she knew things had to change. Years of smoking, drinking, and late-night takeaways at her desk had taken their toll; she was in pain, and she felt... well, old. In her quest to heal her body, Sandra delved into the science of ageing and was astonished by what she found - that ageing is now considered a treatable 'disease', and by addressing its root causes, we can turn back the clock and dramatically extend our health span.

The domestic cat – your cat – has, from its evolutionary origins in Africa, been transformed in comparatively little time into one of the most successful and diverse species on the planet. Jonathan Losos, writing as both a scientist and a cat lover, explores how researchers today are unravelling the secrets of the cat, past and present, using all the tools of modern technology. In addition to solving the mysteries of your cat's past, it gives us a cat's-eye view of today's habitats, including meeting wild cousins around the world whose habits your sweet house cat sometimes eerily parallels.

Marcos Vázquez nos adentra en el proceso de envejecimiento del cuerpo humano para descubrirnos qué es y por qué y cómo envejecemos. Nuestra edad cronológica avanza siempre a la misma velocidad y en la misma dirección, pero nuestra edad biológica es mucho más flexible y moldeable; los últimos avances científicos indican que puede incluso retroceder: REJUVENECER ES POSIBLE.

Synthetic biology promises to reveal how life is created and how it can be re-created, enabling scientists to rewrite the rules of our reality. It could help us, for example, heal without prescription medications, grow meat without harvesting animals, or confront our looming climate catastrophe. Synthetic biology will determine the ways in which we conceive future generations and how we define family, how we identify disease and treat aging, where we make our homes, and how we nourish ourselves.

Best-selling author Brian Fagan brings early humans out of the deep freeze with his trademark mix of erudition, cutting-edge science, and vivid storytelling. Cro-Magnon reveals human society in its infancy, facing enormous environmental challenges - including a rival species of humans, the Neanderthals. For ten millennia, Cro-Magnons lived side by side with Neanderthals, an encounter that Fagan fills with drama.

More than 12,000 years ago, in one of the greatest triumphs of prehistory, humans colonized North America, a continent that was then truly a new world. Just when and how they did so has been one of the most perplexing and controversial questions in archaeology.

We are now on the doorstep of a fourth change brought about by two technologies: AI and robotics. The Fourth Age provides extraordinary background information on how we got to this point, and how - rather than what - we should think about the topics we’ll soon all be facing: machine consciousness, automation, employment, creative computers, radical life extension, artificial life, AI ethics, the future of warfare, superintelligence, and the implications of extreme prosperity.

Molecular biologist Nicklas Brendborg takes us on a journey from farthest reaches of the globe to the most cutting-edge research to explore what nature has to teach us about longevity. From immortal lobsters, backwards-aging jellyfish and the centuries-old Greenland shark to the woman who successfully edited her own DNA in search of immortality, Jellyfish Age Backwards brings together everything the natural world and science have to offer on the mystery of ageing.

First published more than 50 years ago, this award-winning classic brings Rachel Carson's unique vision to a new generation of listeners. The Sense of Wonder is Carson's intimate account of adventures with her young nephew, Roger, as they enjoy walks along the rocky coast of Maine and through dense forests and open fields, observing wildlife, strange plants, moonlight, and storm clouds, and listening to the "living music" of insects in the underbrush.

As recently as 11,000 years ago - "near time" to geologists - mammoths, mastodons, gomphotheres, ground sloths, giant armadillos, native camels and horses, the dire wolf, and many other large mammals roamed North America. In what has become one of science's greatest riddles, these large animals vanished in North and South America around the time humans arrived at the end of the last great ice age.

Over more than 25 years of teaching and research, Christine Desdemaines-Hugon has become an unrivaled expert in the cave art and artists of the Dordogne region. In Stepping-Stones she combines her expertise in both art and archaeology to convey an intimate understanding of the "cave experience." Her keen insights communicate not only the incomparable artistic value of these works but also the near-spiritual impact of viewing them for oneself.

A new gene editing technology, invented just seven years ago, has turned humanity into gods. Enabling us to manipulate the genes in virtually any organism with exquisite precision, CRISPR has given scientists a degree of control that was undreamt of even in science fiction. But CRISPR is just the latest, giant leap in a long journey to master genetics. The Genetic Age shows the astonishing, world-changing potential of the new genetics and the possible threats it poses, sifting between fantasy and the reality when it comes to both benefits and dangers.