Showing results by publisher "Audible Studios" in Genetics

Richard Dawkins' brilliant reformulation of the theory of natural selection has the rare distinction of having provoked as much excitement and interest outside the scientific community as within it. His theories have helped change the whole nature of the study of social biology, and have forced thousands to rethink their beliefs about life.

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

The burgeoning new science of epigenetics offers a cornucopia of insights - some comforting, some frightening. For example, the male fetus may be especially vulnerable to certain common chemicals in our environment, in ways that damage not only his own sperm but also the sperm of his sons. And it’s epigenetics that causes identical twins to vary widely in their susceptibility to dementia and cancer. But here’s the good news: unlike mutations, epigenetic effects are reversible. Indeed, epigenetic engineering is the future of medicine.

Could extinct species, like mammoths and passenger pigeons, be brought back to life? The science says yes. In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks listeners through the astonishing and controversial process of de-extinction.

A preeminent geneticist hunts the Neanderthal genome to answer the biggest question of them all: what does it mean to be human? What can we learn from the genes of our closest evolutionary relatives? Neanderthal Man tells the story of geneticist Svante Pbo’s mission to answer that question, beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in his sequencing of the Neanderthal genome in 2009.

By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.

A tiny mutation on the X chromosome can shape a family’s history. Passed down from a “carrier” parent to a child, fragile X syndrome is the most common inherited cause of intellectual disability and autism. Beyond that—and a rarity among genetic disorders—some fragile X carriers not only transmit the mutation, but also experience related conditions themselves.

In Food, Genes, and Culture, renowned ethnobotanist Gary Nabhan shows why the perfect diet for one person could be disastrous for another. If your ancestors were herders in Northern Europe, milk might well provide you with important nutrients, whereas if you’re Native American, you have a higher likelihood of lactose intolerance. If your roots lie in the Greek islands, the acclaimed Mediterranean diet might save your heart; if not, all that olive oil could just give you stomach cramps.

Where did I come from? Why do I have two arms but just one head? How is my left leg the same size as my right one? Why are the fingerprints of identical twins not identical? How did my brain learn to learn? Why must I die? Questions like these remain biology's deepest and most ancient challenges. They force us to confront a fundamental biological problem: How can something as large and complex as a human body organize itself from the simplicity of a fertilized egg?

Delve deeper into the scientific terms and theories at the core of the Peabody-winning, cult favorite show. With exclusive insights from the show's cocreator, Graeme Manson, and science consultant Cosima Herter, The Science of Orphan Black takes you behind the closed doors of the Dyad Institute and inside Neolution.

While we joke that men are from Mars and women are from Venus, our gender differences can't compare to those of other animals. For instance: the male garden spider spontaneously dies after mating with a female more than fifty times his size. Female cichlids must guard their eggs and larvae--even from the hungry appetites of their own partners. And male blanket octopuses employ a copulatory arm longer than their own bodies to mate with females that outweigh them by four orders of magnitude. Why do these gender gulfs exist?

A panoramic overview of biotechnologies that can endlessly boost human capabilities and the drastic changes these "superhuman" traits could trigger. Biotechnology is moving fast. In the coming decades, advanced pharmaceuticals, bioelectronics, and genetic interventions will be used not only to heal the sick but to boost human physical and mental performance to unprecedented levels.

チャールズ・ダーウィンの『種の起源』は、生物の進化がなぜ起こるのかを自然淘汰で説明し「神が天地創造の際にすべての生き物を完璧な姿でつくった」というキリスト教の世界観を覆した。コペルニクスの地動説と並び、人類に知的革命を起こした大名著である。

人類の歴史は、地球規模の支配を築いた壮大な成功の物語のようにも見える。しかし、その成功の裏で、ホモ・サピエンスはずっと「借りものの時間」を生きてきた。何千年も続いた栄光は、今や終わりが近づいている。なぜそうなったのか？

≪累計300万部突破!『眠れなくなるほど面白い図解シリーズ』≫環境や努力は遺伝に勝てない!?行動遺伝学者が語る“遺伝のタブー”を図解でわかりやすく解説!【遺伝の話】

人間だけがもっているスーパーパワーってなに？　私たちはそれをどう使えばいいんだろう？　世界的ベストセラー『サピエンス全史』の著者が、未来をになう子どもたちに贈る、驚きの歴史！

Una piccola sigla, un mondo di significati: il DNA è una risorsa contro le malattie, uno strumento per identificare gli assassini e una chiave per comprendere il comportamento umano. La sua storia è talmente antica da intrecciarsi con quella della comparsa della vita sulla Terra. E in futuro? Proviamo a parlarne direttamente con lui. Dalla genetica di Neandertal alla clonazione di esseri umani, metteremo a fuoco speranze (e timori) che grazie al DNA si aprono per la scienza e per le nostre esistenze.

I nostri geni non sono scolpiti nella pietra e i nostri fattori ereditari non sono un' "impronta digitale" fissa e immodificabile. Un essere umano infatti è molto più della somma dei suoi geni. Tutto quello che mangiamo, facciamo e sentiamo, tutto ciò che ci accade può influire sull'attività del DNA, a prescindere dalla configurazione genetica con la quale nasciamo. L'epigenetica, cioè la branca della genetica che si occupa di indagare le variazioni dell'espressione del nostro DNA, ci porta infatti una buona notizia: tali variazioni sono reversibili.

From the Siberian permafrost to balmy California, scientists across the globe are working to resurrect all kinds of extinct animals, from ones that just left us to those that have been gone for many thousands of years. Their tools in this hunt are both fossils and cutting-edge genetic technologies. Some of these scientists are driven by sheer curiosity; others view the lost species as a powerful weapon in the fight to preserve rapidly changing ecosystems. It seems certain that these animals will walk the earth again, but what world will that give us? And is any of this a good idea?

Since the birth of civilization, human beings have manipulated other life-forms. We have selectively bred plants and animals for thousands of years to maximize agricultural production and cater to our tastes in pets. The observation of the creation of artificial animal and plant variants was a key stimulant for Charles Darwin's theory of evolution. The ability to directly engineer the genomes of organisms first became possible in the 1970s, when the gene for human insulin was introduced into bacteria.