Showing titles in Genetics

Almost daily, headlines announce newly discovered links between cancers and their genetic causes. Science journalist Jessica Wapner vividly relates the backstory behind those headlines, reconstructing the crucial breakthroughs, explaining the science behind them, and giving due to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 50,000 people diagnosed each year with chronic myeloid leukemia (CML).

One of the biggest discoveries in physics, the quest for the Higgs boson demonstrates the value of a good theory. In July 2012, a Higgs-like particle was found near the energies scientists predicted. Now, armed with better evidence and better questions, the scientific process continues. In this audiobook, we’ve gathered our best reporting to explain that process - the theories, the search, the discovery, and the ongoing questions.

Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way.

In Ancestors in Our Genome, molecular anthropologist Eugene E. Harris presents us with a complete and up-to-date account of the evolution of the human genome and our species. Written from the perspective of population genetics, and in simple terms, the book traces human origins back to their source among our earliest human ancestors, and explains many of the most intriguing questions that genome scientists are currently working to answer.

The science of epigenetics has been scientifically proven to give anyone the power to change the expressions of their genes. Genes can be altered by either the external environmental or internal mental and emotional signals without altering the gene sequence itself. The protocols in this book take a person through the step-by-step process of doing it. By using the detailed processes given, anyone can send new signals to their genes to produce and manufacture the different proteins to restore health, gain new strength, and extend life expectancy.

With all the advances in science in the last century, why are there still so many infectious diseases? Why haven’t we found cures for difficult cancers? Why hasn’t any major progress been made in the treatment of mental illness? And how do we intend to stop, and not only that but reverse, global warming and the climate crisis? In Saved by Science, scientist Mark Poznansky examines the many crises facing humanity while encouraging us with the promise of an emerging solution: synthetic biology.

In Valley of Forgetting, Jennie Erin Smith brings listeners into the clinic, the laboratories, and the Medellín trial center where Lopera’s patients receive an experimental drug to see if Alzheimer’s can be averted. She chronicles the lives of people who care for sick parents, spouses, and siblings, all while struggling to keep their own dreams afloat.

A powerful treatise that demonstrates the existence of altruism in nature, with surprising implications for human society. Does altruism exist? Or is human nature entirely selfish? In this eloquent and accessible book, famed biologist David Sloan Wilson provides new answers to this age-old question based on the latest developments in evolutionary science.

Again and again, microbes have shaped our health, our genetics, our history, our culture, our politics, even our religion and ethics. This book reveals much that scientists and cultural historians have learned about the pervasive interconnections between infectious microbes and humans. It also considers what our ongoing fundamental relationship with infectious microbes might mean for the future of the human species.

One in 3,000 people is born with neurofibromatosis. It affects all of them in different ways. For some, neurofibromatosis is as clear as the tumors on their face. For others, it hides beneath the surface, creating tumors that destroy hearing, vision, and more. Many of them are misdiagnosed, misunderstood, and often simply missed by a world of medicine that doesn't have a full grasp on all the effects of NF.

Few people know much about stem cell research beyond the ethical questions raised by using embryos. But in the last decade, stem cell research has made huge advances toward eliminating some of our most intractable diseases. Now this sweeping and accessible book introduces us to this cutting-edge science, which will revolutionize medicine and change the way we think about and treat disease.

p53: The Gene That Cracked the Cancer Code reveals the tale of the search for this gene, as well as the excitement of the hunt for new cures - the hype, the lost opportunities, the blind alleys, and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is still at the forefront of the game. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.

To make this groundbreaking audiobook, Dr. James Lyons-Weiler combed through the past fifty years of published research on autism, exploring subjects such as genetic variation, mechanisms of neurotoxicity of metals and pesticides, and the central and combined roles of each in causing autism.

If you could bring back one living being from the whole of the history of time, what would you choose? Comedian and former stem-cell biologist Helen Pilcher has thought about this problem - a lot. In Bring Back the King, Helen explains the cutting-edge science that makes the resurrection of extinct animals a very real possibility and highlights her choices from eras gone by, from the king of the dinosaurs, Tyrannosaurus rex, to the King of Rock 'n' Roll, Elvis Presley.

The DNA Restart, by world-renowned neurogeneticist and New York Times best-selling author Dr. Sharon Moalem, walks you through revolutionary steps to a diet and lifestyle perfect for your individual genetic makeup. The DNA Restart plan utilizes decades of in-depth scientific research into genetics, epigenetics, nutrition, and longevity to explain the pivotal role genes play in the journey to ideal weight and health status.

Sociogenomics brings together advances in molecular genetics and traditional social and behavioral science. The key tool is the polygenic index, which allows us to analyze DNA to measure a child's genetic potential. Today, we can estimate a child's adult height, how far they will go in school, and their weight as an adult—all from a cheek swab, finger prick, or vial of saliva. Dalton Conley and other researchers are using this new science to shed light on the ways in which genes shape our world, influencing how each person both creates and responds to the environment around them.

Just 45 years ago, the age of gene modification was born. Researchers could create glow-in-the-dark mice, farmyard animals producing drugs in their milk, and vitamin-enhanced rice that could prevent half a million people going blind every year. But now GM is rapidly being supplanted by a new system called CRISPR or "gene editing". Using this approach, scientists can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago.

At a conference in Hong Kong in November 2018, Dr. He Jiankui announced that he had created the first genetically modified babies - twin girls named Lulu and Nana - sending shockwaves around the world. A year later, a Chinese court sentenced Dr. He to three years in prison for "illegal medical practice". As scientists elsewhere start to catch up with China's vast genetic research program, gene editing is fueling an innovation economy that threatens to widen racial and economic inequality. Fundamental questions about science, health, and social justice are at stake.

In From Darwin to Derrida, evolutionary biologist David Haig explains how a physical world of matter in motion gave rise to a living world of purpose and meaning. Natural selection, a process without purpose, gives rise to purposeful beings who find meaning in the world. The key to this, Haig proposes, is the origin of mutable “texts”―genes―that preserve a record of what has worked in the world. These texts become the specifications for the intricate mechanisms of living beings.

The language of genes has become common parlance. We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise. So we've all heard of genes, but how do they actually work?