Showing titles in Genetics

In this New York Times bestseller and longlist nominee for the National Book Award, “our greatest living chronicler of the natural world” (The New York Times), David Quammen explains how recent discoveries in molecular biology, evolutionary biology, and genetics and genomics affect our...

The discovery of DNA’s structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Howard Markel skillfully recreates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin - fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s - who becomes a focal point for Markel.

For over a century we saw Neanderthals as inferior to Homo Sapiens. After new discoveries, the pendulum swung the other way and they are generally seen as our relatives: not quite human, but similar enough, and still not equal. Now, thanks to an ongoing revolution in palaeoanthropology in which he has played a key part, Ludovic Slimak shows us that they are something altogether different - and they should be understood on their own terms rather than by comparing them to ourselves. As he reveals in this stunning book, the Neanderthals had their own history, their own rituals, their own customs.

Taking us on an incredible journey across centuries and galaxies, accompanied by his characteristic wit, Professor Luke O’Neill explains how it all began, how it will all end and everything in between. Listeners will benefit from Luke’s insatiable curiosity for life when they dive into this ultimate journey through life and death. Among other fascinating facts, you’ll discover the science behind how we got to be so smart, why sex with a caveman was a good idea, the science of finding love, why we follow religions and how robots will become part of everyday life.

Almost daily, headlines announce newly discovered links between cancers and their genetic causes. Science journalist Jessica Wapner vividly relates the backstory behind those headlines, reconstructing the crucial breakthroughs, explaining the science behind them, and giving due to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 50,000 people diagnosed each year with chronic myeloid leukemia (CML).

Stepping effortlessly from myth to cutting-edge science, Mutants gives a brilliant narrative account of our genetic code and the captivating people whose bodies have revealed it - a French convent girl who found herself changing sex at puberty; children who, echoing Homer's Cyclops, are born with a single eye in the middle of their foreheads; a village of long-lived Croatian dwarves; one family, whose bodies were entirely covered with hair, was kept at the Burmese royal court for four generations and gave Darwin one of his keenest insights into heredity.

Genetic engineering, which refers to the direct manipulation of DNA, became a reality in the 1970s. In this audiobook, we take a look at how far the field has come, starting with a revolutionary gene-editing tool called CRISPR that’s taking the research world by storm. We then examine how CRISPR and other approaches are being investigated to treat disease, the fantastic-sounding research being done in synthetic biology, controversial efforts in modifying crops and saving species, as well as the numerous ethical issues raised in these areas.

Today, with relatively easy access to our DNA ancestry, we have more data about ourselves and family history than previous generations could have imagined. In the 12 fascinating lessons of Identity in the Age of Ancestral DNA, Anita Foeman, PhD, professor of communication and media, and founder and primary investigator of the DNA Discussion Project at West Chester University, takes us behind the scenes to examine what really happens when individuals receive their personal DNA ancestry results.

Where did I come from? Why do I have two arms but just one head? How is my left leg the same size as my right one? Why are the fingerprints of identical twins not identical? How did my brain learn to learn? Why must I die? Questions like these remain biology's deepest and most ancient challenges. They force us to confront a fundamental biological problem: How can something as large and complex as a human body organize itself from the simplicity of a fertilized egg?

The Living Spirit of Inquiry explores the deep, timeless questions that lie at the heart of the human experience. With a focus on spiritual philosophy, mythic wisdom, and sacred reflection, this volume invites readers into a journey of meaningful questioning, inner awareness, and contemplative practice.

At a conference in Hong Kong in November 2018, Dr. He Jiankui announced that he had created the first genetically modified babies - twin girls named Lulu and Nana - sending shockwaves around the world. A year later, a Chinese court sentenced Dr. He to three years in prison for "illegal medical practice". As scientists elsewhere start to catch up with China's vast genetic research program, gene editing is fueling an innovation economy that threatens to widen racial and economic inequality. Fundamental questions about science, health, and social justice are at stake.

Just 45 years ago, the age of gene modification was born. Researchers could create glow-in-the-dark mice, farmyard animals producing drugs in their milk, and vitamin-enhanced rice that could prevent half a million people going blind every year. But now GM is rapidly being supplanted by a new system called CRISPR or "gene editing". Using this approach, scientists can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago.

How could a relatively simple chemical code give rise to the complexity of a human being? How could our human genome have evolved? And how does it actually work? Your genome defines you at the most profound level. That same genome is present in every one of the approximately 100,000 billion cells that make you who you are as an individual member of the human species. An important ingredient of the genome, and its essential nature, is memory .

An eye-opening investigation into ancestry and origins in the Middle East that synthesizes thousands of years of genetic history in the region to question what it means to be indigenous to any land “Ancestors transcends geography to launch an eye-opening inquiry into the relationship of...

We are on the cusp of a major transformation in healthcare—yet few people know it. At top hospitals and a few innovative health-tech startups, scientists are working closely with patients to dramatically extend their "healthspan"—the number of healthy years before disease sets in. In The Age of Scientific Wellness, two visionary leaders of this revolution in health take us on a thrilling journey to this new frontier of medicine.

In Food, Genes, and Culture, renowned ethnobotanist Gary Nabhan shows why the perfect diet for one person could be disastrous for another. If your ancestors were herders in Northern Europe, milk might well provide you with important nutrients, whereas if you’re Native American, you have a higher likelihood of lactose intolerance. If your roots lie in the Greek islands, the acclaimed Mediterranean diet might save your heart; if not, all that olive oil could just give you stomach cramps.

From the author of Seed of Israel: DNA Guide to Tracing Your Jewish Ancestry comes this great dive into the history of Ashkenazi Jews. While controversial debates spark disagreements on the crystallization of this Jewish Diaspora, modern genetic studies and personal DNA samples finally conclude the Levantine Middle Eastern and Mediterranean roots of Ashkenazi ancestry: Judean people from the Holy Land that journeyed across the Mediterranean to the bottleneck of Europe.

In this exploration of the concept of the gene, Jonathan Slack looks at the discovery, nature, and role of genes in both evolution and development. Explaining the nature of genetic variation in the human population, how hereditary factors were identified as molecules of DNA, and how certain specific mutations can lead to disease, Slack highlights how DNA variants are used to trace human ancestry and migration, and can also be used by forensic scientists to identify individuals in crime.

In From Darwin to Derrida, evolutionary biologist David Haig explains how a physical world of matter in motion gave rise to a living world of purpose and meaning. Natural selection, a process without purpose, gives rise to purposeful beings who find meaning in the world. The key to this, Haig proposes, is the origin of mutable “texts”―genes―that preserve a record of what has worked in the world. These texts become the specifications for the intricate mechanisms of living beings.

To make this groundbreaking audiobook, Dr. James Lyons-Weiler combed through the past fifty years of published research on autism, exploring subjects such as genetic variation, mechanisms of neurotoxicity of metals and pesticides, and the central and combined roles of each in causing autism.