Showing results by publisher "----RM Alexander" in Evolution & Genetics

Cancer has always been with us. It killed our hominid ancestors, the mammals they evolved from and the dinosaurs that trampled the ground before that. Tumours grow in pets, livestock and wild animals. Even tiny jelly-like Hydra - creatures that are little more than a tube full of water - can get cancer. Paradoxically, many of us think of cancer as a contemporary killer, a disease of our own making caused by our modern lifestyles.

Our Political Nature is the first book to reveal the hidden roots of our most deeply held moral values. It shows how political orientations across space and time arise from three clusters of measurable personality traits. These clusters entail opposing attitudes toward tribalism, inequality, and differing perceptions of human nature. Together, these traits are by far the most powerful cause of left-right voting, even leading people to regularly vote against their economic interests.

For decades after the structure of DNA was identified, scientists focused purely on genes, the regions of the genome that contain codes for the production of proteins. Other regions - 98 percent of the human genome - were dismissed as ‘junk’. But in recent years researchers have discovered that variations in this ‘junk’ DNA underlie many previously intractable diseases, and they can now generate new approaches to tackling them.

Among the estimated 100 billion solar systems in the known universe, evolving life is surely abundant. That evolution is a process of "becoming" in each case. Since Newton, we have turned to physics to assess reality. But physics alone cannot tell us where we came from, how we arrived, and why our world has evolved past the point of unicellular organisms to an extremely complex biosphere.

In Born in Africa, Martin Meredith follows the trail of discoveries about human origins made by scientists over the last hundred years, recounting their intense rivalry, personal feuds, and fierce controversies, as well as their feats of skill and endurance. The results have been momentous. Scientists have identified more than 20 species of extinct humans. They have firmly established Africa as the birthplace not only of humankind but also of modern humans.

Charles Darwin’s theories, first published more than 150 years ago, still set the paradigm of how we understand the evolution of life--but scientific advances of recent decades have radically altered that. Now two pioneering scientists draw on their years of experience in paleontology, biology, chemistry, and astrobiology to deliver an eye-opening narrative using a generation’s worth of insights culled from new research.

No other life form on the planet has generated a brain like ours. How did a bundle of cells weighing just 1.2 kg give rise to conscious, self-aware beings capable of understanding time, language, mathematics and music, of exploring outer space and sequencing their own DNA? The answer to such questions is a seven-million-year saga. How the Mind Changed is the definitive audiobook on human brain evolution: a sweeping natural history.

Lately, the most passionate advocates of the theory of evolution seem to present it as bad news. Scientists such as Richard Dawkins, Lawrence Krauss, and Sam Harris tell us that our most intimate actions, thoughts, and values are mere byproducts of thousands of generations of mindless adaptation. We are just one species among multitudes and therefore no more significant than any other living creature. Now comes Brown University biologist Kenneth R. Miller to make the case that this view betrays a gross misunderstanding of evolution.

Edward Larson's classic, Summer for the Gods, received the Pulitzer Prize in History in 1998 and is the single most authoritative account of a pivotal event whose combatants remain at odds in school districts and courtrooms. For this edition Larson has added a new preface that assesses the state of the battle between creationism and evolution and points the way to how it might potentially be resolved.

Few people know much about stem cell research beyond the ethical questions raised by using embryos. But in the last decade, stem cell research has made huge advances toward eliminating some of our most intractable diseases. Now this sweeping and accessible book introduces us to this cutting-edge science, which will revolutionize medicine and change the way we think about and treat disease.

For all that science knows about the living world, notes David P. Barash, there are even more things we don't know, genuine evolutionary mysteries that perplex the best minds in biology. Paradoxically, many of these mysteries are very close to home, involving some of the most personal aspects of being human. Homo Mysterious examines a number of these evolutionary mysteries, exploring things we don't yet know about ourselves, laying out the best current hypotheses, and pointing toward insights that scientists are just beginning to glimpse.

Darwin developed the theory of sexual selection to explain why the animal world abounds in stunning beauty, from the brilliant colors of butterflies and fishes to the songs of birds and frogs. He argued that animals have "a taste for the beautiful" that drives their potential mates to evolve features that make them more sexually attractive and reproductively successful. But if Darwin explained why sexual beauty evolved in animals, he struggled to understand how.

Nearly every depressed person is assured by doctors, well-meaning friends and family, the media, and ubiquitous advertisements that the underlying problem is a chemical imbalance. Such a simple defect should be fixable, yet despite all of the resources that have been devoted to finding a pharmacological solution, depression remains stubbornly widespread. Why are we losing this fight?

In 2010, scientists led by J. Craig Venter became the first to successfully create "synthetic life" - putting humankind at the threshold of the most important and exciting phase of biological research, one that will enable us to actually write the genetic code for designing new species to help us adapt and evolve for long-term survival. The science of synthetic genomics will have a profound impact on human existence, including chemical and energy generation, health, clean water and food production, environmental control, and possibly even our evolution.

In this engaging exploration, archaeologist Ian Hodder departs from the two prevailing modes of thought about human evolution: the older idea of constant advancement toward a civilized ideal and the newer one of a directionless process of natural selection. Instead, he proposes a theory of human evolution and history based on "entanglement," the ever-increasing mutual dependency between humans and things.

We've all asked ourselves the question. It's impossible to look up at the stars and NOT think about it: Are we alone in the universe? Books, movies, and television shows proliferate that attempt to answer this question and explore it. In Out There, Space.com senior writer Dr. Michael Wall treats that question as merely the beginning, touching off a wild ride of exploration into the final frontier. He considers, for instance, the myriad of questions that would arise once we do discover life beyond Earth (an eventuality which, top NASA officials told Wall, is only drawing closer).

Genetic engineering, which refers to the direct manipulation of DNA, became a reality in the 1970s. In this audiobook, we take a look at how far the field has come, starting with a revolutionary gene-editing tool called CRISPR that’s taking the research world by storm. We then examine how CRISPR and other approaches are being investigated to treat disease, the fantastic-sounding research being done in synthetic biology, controversial efforts in modifying crops and saving species, as well as the numerous ethical issues raised in these areas.

At a conference in Hong Kong in November 2018, Dr. He Jiankui announced that he had created the first genetically modified babies - twin girls named Lulu and Nana - sending shockwaves around the world. A year later, a Chinese court sentenced Dr. He to three years in prison for "illegal medical practice". As scientists elsewhere start to catch up with China's vast genetic research program, gene editing is fueling an innovation economy that threatens to widen racial and economic inequality. Fundamental questions about science, health, and social justice are at stake.

The cells in our bodies consist of molecules, made up of the same carbon, oxygen, and hydrogen atoms found in air and rocks. But molecules, such as water and sugar, are not alive. So how do our cells - assemblies of otherwise "dead" molecules - come to life, and together constitute a living being? In Life’s Ratchet, physicist Peter M. Hoffmann locates the answer to this age-old question at the nanoscale.

Just 45 years ago, the age of gene modification was born. Researchers could create glow-in-the-dark mice, farmyard animals producing drugs in their milk, and vitamin-enhanced rice that could prevent half a million people going blind every year. But now GM is rapidly being supplanted by a new system called CRISPR or "gene editing". Using this approach, scientists can manipulate the genes of almost any organism with a degree of precision, ease and speed that we could only dream of ten years ago.