Showing titles in Evolution & Genetics

Genetic engineering, which refers to the direct manipulation of DNA, became a reality in the 1970s. In this audiobook, we take a look at how far the field has come, starting with a revolutionary gene-editing tool called CRISPR that’s taking the research world by storm. We then examine how CRISPR and other approaches are being investigated to treat disease, the fantastic-sounding research being done in synthetic biology, controversial efforts in modifying crops and saving species, as well as the numerous ethical issues raised in these areas.

More than half a billion years ago, our world was completely covered by glaciers, a "Snowball Earth" that persisted for millions of years. Incredibly, this unimaginable cold led to the remarkable diversification of life on earth known as the Cambrian explosion. With a geologist's eye and a knack for storytelling, Graham Shields explores when and how such inhospitable conditions enabled animals to evolve, radiate, and diversify into our earliest ancestors.

In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease.

In 1955, on a visit to South Africa, Robert Ardrey became aware of the growing evidence that man had evolved on the African continent from carnivorous, predatory stock - ones who had also, long before man, achieved the use of weapons. A dramatist, Ardrey's interest in the African discoveries sprang less from purely scientific grounds than from the radical new light they cast on the eternal question: Why do we behave as we do? Are we naturally inclined towards war and weapons?

When we think of the forces driving cancer, we don’t necessarily think of evolution. But evolution and cancer are closely linked, for the historical processes that created life also created cancer. The Cheating Cell delves into this extraordinary relationship, and shows that by understanding cancer’s evolutionary origins, researchers can come up with more effective, revolutionary treatments.

The Apples, Amazons and Googles of the next few decades will be biotech companies. The tech companies of the last few years have changed how we do things but the businesses driving the biotech revolution are about making life better. These companies will solve many of our most intractable problems: cancer, dementia, diabetes, elderly care, mental health challenges, even power generation and agricultural production. Biotech will mean that we can live far better, safer, healthier, wealthier, happier, and longer lives.

What defines who we are? For decades, the biological answer has been our genes. In The Master Builder, leading biologist Alfonso Martinez Arias breaks with decades of scientific and popular tradition to make a bold argument: what defines us is our cells. Drawing on new research from his lab and others, Martinez Arias reveals that we are composed of a thrillingly complex, constantly rearranging symphony of cells that know how to count, feel, and ultimately give form to our bodies.

A list of the attributes that define a mammal is a ragbag of things - fur, live birth, three bones in the middle ear, a brain whose two halves are robustly joined together.... But this curious collection of features contain the roots of all the biology that makes us what we are: monkeys with massive brains who parent extensively, enjoy sport and think lots. Which is to say, what makes us mammals makes us human.

Humans are the only species who can reprogram themselves. This is astounding. In episode 8 of The Book Club, Amit Varma recommends you read 'Hacking Darwin' by Jamie Metzl, a lucid summation of the technological implications of genetic science – and the ethical questions they raise.

SHORTLISTED FOR THE 2018 BAILLIE GIFFORD PRIZE FOR NON-FICTION 'Elegantly written, wittily constructed . . . My science book of the year.' Robin McKie, Observer, 'Best Books of 2018' She Has Her Mother’s Laugh presents a profoundly original perspective on what we pass along from generation to...

What makes us human? Why are we the only animals who wear clothes, drive cars, trawl the internet, and fly helicopters on Mars? It’s all because we’ve learnt to talk, yet remarkably, we still don’t know how we did it. Speech! suggests an answer that’s been hiding in plain sight - the simple yet radical shift that turned our analog grunts and shrieks into words. But, its consequences are far from simple: being able to share ideas through language was an evolutionary tipping point - it allowed us to link up our minds.

Was ist Leben? Und was bedeutet die Antwort auf diese Frage für die Herausforderungen, denen sich die Menschheit heute gegenübersieht - Klimawandel, Pandemien und Artensterben? Paul Nurse erhielt den Nobelpreis dafür, gezeigt zu haben, wie lebende Zellen funktionieren. In seinem so klar wie elegant verfassten Buch synthetisiert er auf wenigen Seiten sämtliches Wissen darüber, was es heißt, am Leben zu sein. Schritt für Schritt erläutert Nurse die fünf revolutionären Ideen, die der Biologie zugrunde liegen - die Zelle, das Gen, Evolution durch natürliche Selektion, das Leben als Chemie und das Leben als Information.

Evolutionary theory in the theme that binds together these essays on such seemingly disparate topics as the feeding habits of flamingos, flowers and snails that change from male to female and sometimes back again, and the extinction from baseball of the .400 hitter.

In this book, the author uses chronological evolution as the outline as we observe the foundations of our universe and the unfolding of the phenomenon of "man". The evolutionary process as explained in the Human Phenomenon, a new edition of de Chardin's The Phenomenon of Man (1065 English edition), as edited and translated from the French 1955 edition by Sarah Appleton Weber in 1999, is categorized under four parts: prelife, life, thought, and superlife.

For a long time, scientists have wondered how life has emerged from inanimate chemistry, and whether Earth is the only place where it exists. Charles Darwin speculated about life on Earth beginning in a warm little pond. Some of his contemporaries believed that life existed on Mars. It once seemed inevitable that the truth would be known by now. It is not. For more than a century, the origins and extent of life have remained shrouded in mystery. But, as Mario Livio and Jack Szostak reveal in Is Earth Exceptional?, the veil is finally lifting.

All of us would like to live longer, or to slow the debilitating effects of age. In How We Age, Coleen Murphy shows how recent research on longevity and aging may be bringing us closer to this goal. Murphy, a leading scholar of aging, explains that the study of model systems, particularly simple invertebrate animals, combined with breakthroughs in genomic methods, have allowed scientists to probe the molecular mechanisms of longevity and aging.

Nearly every depressed person is assured by doctors, well-meaning friends and family, the media, and ubiquitous advertisements that the underlying problem is a chemical imbalance. Such a simple defect should be fixable, yet despite all of the resources that have been devoted to finding a pharmacological solution, depression remains stubbornly widespread. Why are we losing this fight?

On his popular science blog, Pharyngula, PZ Myers has entertained millions of fans with his infectious love of evolutionary science and his equally infectious disdain for creationism, biblical literalism, intelligent design theory, and other products of godly illogic. This funny and fearless book collects and expands on some of his most popular writings, giving the religious fanaticism of our times the gleeful disrespect it deserves by skewering the apocalyptic fantasies, magical thinking, hypocrisies, and pseudoscientific theories advanced by religious fundamentalists of all stripes.

In this engaging exploration, archaeologist Ian Hodder departs from the two prevailing modes of thought about human evolution: the older idea of constant advancement toward a civilized ideal and the newer one of a directionless process of natural selection. Instead, he proposes a theory of human evolution and history based on "entanglement," the ever-increasing mutual dependency between humans and things.

Biogeography is the study of geographic variation in all characteristics of life - ranging from genetic, morphological, and behavioral variation among regional populations of a species, to geographic trends in diversity of entire communities across our planet's surface. From the ancient hunters and gatherers to the earliest naturalists, Charles Darwin, Alfred Russel Wallace, and scientists today, the search for patterns in life has provided insights that proved invaluable for understanding the natural world.