Showing titles in Evolution & Genetics

Could extinct species, like mammoths and passenger pigeons, be brought back to life? The science says yes. In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks listeners through the astonishing and controversial process of de-extinction.

Throughout history, people have sought to reduce suffering, eliminate disease and enhance desirable qualities in their children. In the Victorian era eugenics, a full-blooded attempt to impose control over unruly biology, began to grow among the powerful and quickly spread to dozens of countries around the world. But these ideas are not merely historical: today, with new gene editing techniques, conversations are happening about tinkering with the DNA of our unborn children to make them smarter, fitter, stronger.

An entertaining deep dive into muscle, from the discovery of human anatomy to the latest science of strength training.

DNA Demystified satisfies the public appetite for and curiosity about DNA and genetics. The book begins with the basic groundwork and a brief history of DNA and genetics. Chapters then cover newsworthy topics, including DNA fingerprinting, using DNA in forensic analyses, and identifying cold-case criminals. For listeners intrigued by the proliferation of at-home DNA tests, the text includes fascinating explorations of genetic genealogy and family tree construction.

Nearly every depressed person is assured by doctors, well-meaning friends and family, the media, and ubiquitous advertisements that the underlying problem is a chemical imbalance. Such a simple defect should be fixable, yet despite all of the resources that have been devoted to finding a pharmacological solution, depression remains stubbornly widespread. Why are we losing this fight?

Humans are the only mammals to walk on two, rather than four, legs. From an evolutionary perspective, this is an illogical development, as it slows us down. But here we are, suggesting there must have been something tremendous to gain from bipedalism. First Steps takes our ordinary, everyday walking experience and reveals how unusual and extraordinary it truly is. The seven-million-year-long journey through the origins of upright walking shows how it was in fact a gateway to many of the other attributes that make us human.

Astrobiology is an exciting new subject, and one, arguably, more interdisciplinary than any other. Astrobiologists seek to understand the origin and evolution of life on Earth in order to illuminate and guide the search for life on other planets. In this Very Short Introduction, David C. Catling introduces the subject through our understanding of the factors that allowed life to arise and persist on our own planet, and for the signs we are looking for in the search for extraterrestrial life.

The scientific evidence behind why maintaining a lifestyle more like that of our ancestors will restore our health and well-being. In Go Wild, Harvard Medical School Professor John Ratey, MD, and journalist Richard Manning reveal that although civilization has rapidly evolved, our bodies have not kept pace.

In Origins, Frank H. T. Rhodes explores the origin and evolution of living things, the changing environments in which they have developed, and the challenges we now face on an increasingly crowded and polluted planet. Rhodes argues that the future well-being of our burgeoning population depends in no small part on our understanding of life's past, its long and slow development, and its intricate interdependencies.

Perched on the exterior of our delicate and intricate bodies, the skin is our largest and fastest growing organ. We see it, touch it and live in it every day. It's a habitat for a mesmerisingly complex world of micro-organisms, its physical functions are vital to our health and indeed our survival, and it's crucial to our sense of identity. Yet how much do we really know about it? Through the lenses of science, sociology and history, Dr Monty Lyman leads us on a journey through the comedy, tragedy and exquisite humanity of our most underrated and overlooked organ.

When we think of the forces driving cancer, we don’t necessarily think of evolution. But evolution and cancer are closely linked, for the historical processes that created life also created cancer. The Cheating Cell delves into this extraordinary relationship, and shows that by understanding cancer’s evolutionary origins, researchers can come up with more effective, revolutionary treatments.

How did life begin? It is perhaps the most important question science has ever asked. Over the centuries, the search for an answer has been entwined with some of science's most revolutionary advances, including van Leeuwenhoek's microscope, Darwin's theory of evolution, and Crick and Watson's unveiling of DNA.

How does life work? How does nature produce the right numbers of zebras and lions on the African savanna, or fish in the ocean? How do our bodies produce the right numbers of cells in our organs and bloodstream? In The Serengeti Rules, award-winning biologist and author Sean B. Carroll tells the stories of the pioneering scientists who sought the answers to such simple yet profoundly important questions.

To the modern mind, the idea of honor is outdated, sexist, and barbaric. It evokes Hamilton and Burr and pistols at dawn, not visions of a well-organized society. But for philosopher Tamler Sommers, a sense of honor is essential to living moral lives. In Why Honor Matters, Sommers argues that our collective rejection of honor has come at great cost. Reliant only on Enlightenment liberalism, the United States has become the home of the cowardly, the shameless, the selfish, and the alienated. Properly channeled, honor encourages virtues like courage, integrity, and solidarity.

If you think you are you, think again. Primate Change is a wide-ranging, polemical look at how and why the human body has changed since humankind first got up on two feet. Spanning the entirety of human history - from primate to transhuman - Vybarr Cregan-Reid's book investigates where we came from, who we are today and how modern technology will change us beyond recognition.

For decades medical science has believed that genes determined our biological destiny. Now the new genetics has changed that assumption forever. You will always have the genes you were born with, but genes are dynamic, responding to everything we think, say, and do. Suddenly they've become our strongest allies for personal transformation. When you make lifestyle choices that optimize how your genes behave, you can reach for a state of health and fulfillment undreamed of even a decade ago.

"It's the animal in us," we often hear when we've been bad. But why not when we're good? Primates and Philosophers tackles this question by exploring the biological foundations of one of humanity's most valued traits: morality.In this provocative book, primatologist Frans de Waal argues that modern-day evolutionary biology takes far too dim a view of the natural world, emphasizing our "selfish" genes.

The burgeoning new science of epigenetics offers a cornucopia of insights - some comforting, some frightening. For example, the male fetus may be especially vulnerable to certain common chemicals in our environment, in ways that damage not only his own sperm but also the sperm of his sons. And it’s epigenetics that causes identical twins to vary widely in their susceptibility to dementia and cancer. But here’s the good news: unlike mutations, epigenetic effects are reversible. Indeed, epigenetic engineering is the future of medicine.

How did human minds become so different from those of other animals? What accounts for our capacity to understand the way the physical world works, to think ourselves into the minds of others, to gossip, read, tell stories about the past, and imagine the future? These questions are not new: they have been debated by philosophers, psychologists, anthropologists, evolutionists, and neurobiologists over the course of centuries. One explanation widely accepted today is that humans have special cognitive instincts.

The cells in our bodies consist of molecules, made up of the same carbon, oxygen, and hydrogen atoms found in air and rocks. But molecules, such as water and sugar, are not alive. So how do our cells - assemblies of otherwise "dead" molecules - come to life, and together constitute a living being? In Life’s Ratchet, physicist Peter M. Hoffmann locates the answer to this age-old question at the nanoscale.