TWiM explains a candidate signature of health in the gut microbial community, and how an intestinal bacterium exacerbates cardiac ischemia/reperfusion injury.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson and Petra Levin.

Become a patron of TWiM.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

• A candidate signature of health in the gut microbiome (Cell Host Microbe)
• 204,938 reference genomes from the human gut microbiome (Nat Biotech)
• A human gut metagenome-assembled genome catalogue spanning 41 countries (Nat Micro)
• A comprehensive ruminant microbial catalog (Gigascience)
• Bacteroides acidifaciens exacerbates cardiac ischemia/reperfusion injury (Cell Host Microbe)
• The Great Ozempic Experiment (NY Times, paywall)
• Take the TWiM Listener survey!

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

TWiM explains how to use microbes to enhance maize yield and reduce corn rootworm damage, and how the human microbiota modulates IgE-mediated reactions to foods through allergen metabolism.

Hosts: Michael Schmidt, Petra Levin, and Michele Swanson.

Guest: Mark O. Martin

Become a patron of TWiM.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

• Harnessing Microbes for Crop Production (Phytobiome J)
• Microbes take on corn rootworm (Science)
• Microbial metabolism of food allergens (Cell Host Microbe)
• Take the TWiM Listener survey!

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

TWiM reveals the archaeal roots of eukaryotic life, and a building a gut malabsorption biosensor with bacteria.

Become a patron of TWiM.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

• The archaeal roots of eukaryotic life (PNAS)
• Building a malabsorption biosensor (Cell)
• Engineering gut biosensors with microbes (Natuer)
• Take the TWiM Listener survey!

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

TWiM discusses the use of bacteriophage-loaded microneedle patches for targeted and minimally disruptive foodborne pathogen decontamination, and a conjugal gene drive-like system that efficiently suppresses antibiotic resistance in bacteria.

Become a patron of TWiM.

Links for this episode:

• Bacteriophage-loaded microneedle patches for food (Sci Adv)

• Gene drive to suppress antibiotic resistance (npj antimicrob and resistance)

• CRISPR gene drives (Syntego)

• Bier laboratory

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

Nancy and Maggie join TWiM to share how and why they created a freely available ebook of TWiM-based science literacy resources and classroom exercises that support teaching across key microbiology and molecular biology topics.

Become a patron of TWiM.

Links for this episode:

• Podcast annotation and resources in microbiology (Iowa State U)

• Curriculum guidelines for undergraduate microbiology (ASM)
  
  

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

TWiM explains how mechano-bactericidal surfaces made from diverse materials and patterned with spikes kill bacteria on contact, and virus-host evolution is reshaped by microgravity aboard the International Space Station.

Become a patron of TWiM.

Links for this episode:

• Mechano-Bactericidal Surfaces (Adv Sci)

• Piercing pathogens (ASM)

• Natural bactericidal surfaces (Small)

• Virus-host evolution in microgravity (PLoS Biol)
  
  

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

TWiM explains the finding that owning a dog during adolescence alters the microbiota and improves mental health, and the molecular basis for multidrug efflux by an anaerobic-associated resistance-nodulation-cell division transporter.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson and Petra Levin.

Become a patron of TWiM.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

• Dog ownership and the microbiome during adolescence (iScience)
• Molecular basis for multidrug efflux (Nat Comm)
• Take the TWiM Listener survey!

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

TWiM explains how S. aureus pathogenicity is a dynamic, niche-specific choreography that constantly recalibrates in response to the host microenvironment, and short chain fatty acids produced by commensal microbiota reduces its competitive fitness.

Become a patron of TWiM.

Links for this episode:

• Niche-specific fitness of S. aureus at the wound edge (Nat Comm)

• Commensal derived short chain fatty acids attenuate S. aureus (mBio)

• Ditch the term pathogen (Nature)
  

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv