Where did the 10,000 steps recommendation come from? Why has it proven so stubborn? What's the science behind the new recommendations? How strong is the evidence?

Professor Melody Ding joins Gavin to talk about her new systematic review published in The Lancet Public Health, examining the relationship between step counts and health outcomes. We also explore the challenges of measuring physical activity, the importance of inclusive research, and the role of environmental and policy interventions in promoting population health.

Read the article from The Lancet Public Health here:

https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(25)00164-1/fulltext?dgcid=buzzsprout_tlv_podcast_August_25_lanpub

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It’s no exaggeration to say that the past decade has revolutionized how we think about and treat obesity. Drugs like semaglutide (Wegovy) and tirzepatide (Zepbound) have dominated headlines, enabling significant weight loss at speeds once considered unthinkable. The market for innovative weight loss medications is booming, with pharmaceutical companies investing heavily in hopes of developing the next blockbuster drug.

However, amid this race for market dominance, many experts are questioning whether the amount of weight loss alone is the best measure of these drugs’ usefulness. How can the next generation of obesity treatments meaningfully improve upon the powerful options already available?

Joining The Lancet editors Callam Davidson and Miriam Sabin to discuss this question is Professor Steven Heymsfield from the Pennington Biomedical Research Center. This wide-ranging conversation covers exciting pharmaceutical advances and limitations of these treatments, including the significant disparities in access, and why these breakthroughs may have broader societal implications.

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The sustainability of our existence relies on the health of every human, every animal, and the environment we all share. Published today, "The Lancet One Health Commission: harnessing our interconnectedness for equitable, sustainable, and healthy socioecological systems" highlights challenges like climate change, food security, and antimicrobial resistance to lay out the One Health approach to informing and implementing solutions.

Senior Executive Editor at The Lancet Pam Das is joined by lead Commissioners, Andrea Winkler and John Amuasi, to explain the past, present, and future of the One Health concept.

You can read the Commission here:

https://www.thelancet.com/commissions-do/one-health?dgcid=buzzsprout_tlv_podcast_lancetonehealth25_lancet

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