Episodes

  • Glycogen Summary: Liver vs Muscle
    Dec 23 2025

    This podcast summarizes glycogen metabolim hidhlighting some of the major differences between liver and muscle glycogenolysis. In addition, allosteric and hormonal regulation of glycogenolysis in both tissues are covered in detail.

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    10 mins
  • Understanding Metabolism
    Dec 16 2025

    This podcast provides a detailed overview of metabolism, defining it as the complete set of cellular processes essential for survival, which are categorized into catabolic (energy-producing breakdown) and anabolic (energy-consuming synthesis) pathways. It emphasizes that metabolic regulation is heavily dependent on three main factors: hormone levels (particularly insulin and glucagon from the pancreas), the availability of substrates in the bloodstream, and input from the nervous system. The text further explains the metabolic shifts that occur during the well-fed state, where insulin dominates to promote glucose storage and uptake, versus the fasting state, where glucagon and stress hormones increase glucose production and shift tissues toward utilizing fatty acids and ketone bodies for energy. Specifically, the regulation of blood glucose by these key hormones is highlighted, demonstrating their antagonistic roles in maintaining energy homeostasis.



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    11 mins
  • Catabolism of D/L Amino Acids
    Dec 13 2025

    In nature, amino acids exist as two distinct isomers, designated D and L Isomers. These mirror images of one another are metabolized differently in the cell. Only L isomers are used in cellular protein synthesis. Most catabolic enzymes metabolize L-isomers only while D-isomers are metabolized by D-Amino acid oxidase.

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    3 mins
  • FAT: The most Abundant Energy Depot in The Body - AI Podcast
    Nov 28 2025

    This YouTube video transcript from "Metabolism Made Easy" highlights the significant role of fat reserves in the human body. The speaker emphasizes the substantial quantity of fat, primarily in the form of triacylglycerols (TAGs), stored within us. This reserve represents a considerable percentage of body mass and, crucially, an enormous energy depot. The transcript points out that the caloric potential of fat far surpasses that of both protein and glycogen, making it the body's most important long-term energy source.

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    3 mins
  • The TCA Cycle: A Central Role in Metabolism
    Nov 22 2025

    In addition to providing significant energy through the oxidation of Acetyl CoA, the TCA cycle plays important roles in anabolic processes like gluconeogenesis, ketogenesis, fatty acid, and cholesterol biosynthesis by providing essential precursors for those processes.

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    3 mins
  • Amino Acid Carbon Skeletons
    Nov 15 2025

    Catabolism of amino acids involves the removal of nitrogen by either specific transaminases or by glutamate dehydrogenase. These pathways will produce alpha-keto acids/ carbon skeletons which can be used for energy production or biosynthesis of other molecules.

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    3 mins
  • Amino Acid Functional Groups I
    Nov 10 2025

    Amino acids are defined by two functional groups: An amino group and a carboxylic group. Both groups can donate/accept protons under specific pH conditions. At a neural pH (7.0) amino acids exist in the zwitterionic form of NH3 + and COO-.

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    3 mins
  • Amino Acid Catabolism: The Mandatory Urea Cycle -AI Podcast
    Nov 1 2025

    The source, an excerpt from the YouTube video "Catabolism of Amino Acids @Metabolism Made Easy," discusses the unique aspects of amino acid metabolism. It explains that amino acids are the sole nitrogen-containing molecules utilized by the body, which leads to the eventual production of ammonia during catabolism. To manage this toxic byproduct, the body employs the urea cycle to safely eliminate the nitrogen. The video also highlights that unlike glucose or fatty acids, the body lacks a storage mechanism for excess amino acids, meaning any surplus not used for synthesizing proteins or specialized products is broken down. This catabolism generates a carbon skeleton or keto acid that can then be used by the body for energy production.



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    10 mins