Hi everyone.

Happy New Year.

As the new year 2026 unfolds, I want to share three things in this episode.
1. What I hope LipidCurious continues to represent.
2. What I’m working on right now.
3. How I’m thinking about content on this platform moving forward.

I see LipidCurious as a shared journey between you and me. Let’s build it thoughtfully, together.

If you have ideas you’d like to share, I’d love to hear from you. This includes:

• Topics you'd like to be discussed in an episode
• Collaboration idea with groups or societies aligned with the mission of expanding cardiometabolic medicine.
• Mentors in the cardiometabolic space you’d love to see highlighted in an episode
• Cardiometabolic or lipid-focused training opportunities for our colleagues to explore.
• Non-clinical topic you want discussed in a future episode.

You can reach me anytime at hello@lipidcurious.com

Download the Free LipidCurious Starter Kit here

Disclaimer: This podcast is intended for educational purposes for clinicians and healthcare professionals. It does not provide medical advice, establish a physician–patient relationship, or replace individualized clinical judgment. The opinions expressed are those of the creator and do not represent the views of any affiliated institutions or organizations.

Inflammation!

We use the word all day in the clinic. We blame it for half the problems in medicine. Yet when you strip it down to its core, inflammation is one of the most misunderstood forces in cardiometabolic medicine.

In this episode of LipidCurious, we discuss

1. What is inflammation?

2. How do we measure it?

3. How do we treat it?

By the end, you’ll walk away with a sharper, cleaner understanding of inflammation’s role in cardiometabolic disease — and how to act on it in everyday practice.

And finally, a heartfelt wrap-up of Season 1, the journey behind building LipidCurious, and where this platform may go next.

Bonus: For the full collection of visuals across Season 1, visit the Podcast page.

Download the Free LipidCurious Starter Kit here

Questions or feedback? Reach out at hello@lipidcurious.com

Disclaimer: This podcast is for educational purposes only. It is NOT medical advice.

Most heart attacks don’t start with a clogged artery! They start with a microscopic storm — a small, invisible wound inside the artery wall.

That storm begins decades before symptoms, sometimes before high school. By the time someone hits their forties or fifties, the real question isn’t whether atherosclerosis has begun…It’s how far it’s already gone.

Let’s zoom in — literally inside the artery wall — and trace this disease from its very first spark.
From the moment an ApoB-containing particle sneaks beneath the endothelium…
To the slow, simmering inflammation that follows…
To the day a plaque finally stops being silent.

In this episode of LipidCurious, we’ll uncover

1. Anatomy & The Birth of an Atherosclerotic Plaque
2. Why Some Arteries Are More Prone to Atherosclerosis
3. Seeing, Treating, and Reversing Atherosclerosis

You’ll walk away seeing cholesterol numbers in a completely different light — not as abstract labs, but as a daily pressure on the artery wall.

By the end, you’ll understand why atherosclerosis is the slow burn beneath the surface — invisible for years, yet capable of erupting into the events we fear most.

Bonus: The Visual Guide for this episode is waiting for you — click here. For the full collection of visuals across episodes, visit the Podcast page.

Download the Free LipidCurious Starter Kit here

Questions or feedback? Reach out at hello@lipidcurious.com

Disclaimer: This podcast is for educational purposes only. It is NOT medical advice.

LDL may get all the blame — but there’s a darker twin hiding in the shadows.
Same cholesterol core. Same ApoB backbone.
But with one sinister twist: a sticky tail called apolipoprotein(a).
That extra piece transforms an ordinary LDL particle into something far more dangerous.

Meet Lipoprotein(a) — or Lp(a) — one of the strongest, most under-recognized genetic drivers of premature cardiovascular disease.
It’s pro-atherogenic, pro-thrombotic, and pro-inflammatory — a triple threat that can quietly turn even the healthiest-looking lipid panel into a ticking time bomb.

In this episode of LipidCurious, we’ll uncover

1. What is Lp(a)?

2. How and when to test for it?

3. What to do when Lp(a) is high?

We’ll walk through genetics, testing strategy, and real-world management — plus a glimpse into the promising therapies now in late-phase trials.
By the end, you’ll understand why Lp(a) is the ghost in the lipid story — invisible on a standard panel, but capable of haunting even the fittest hearts.

Bonus: The Visual Guide for this episode is waiting for you — click here. For the full collection of visuals across episodes, visit the Podcast page.

Download the Free LipidCurious Starter Kit here

Questions or feedback? Reach out at hello@lipidcurious.com

Disclaimer: This podcast is for educational purposes only. It is NOT medical advice.

LDL-C is the number we’ve all been trained to chase. But what if the real culprit isn’t the cholesterol itself… but the number of particles carrying it?

Meet ApoB — the quiet truth-teller of lipidology.
It doesn’t care how perfect your LDL number looks. It counts every atherogenic particle capable of injuring the arterial wall — the true measure of risk hiding beneath the surface.

In this episode of LipidCurious, we’ll dig into what makes ApoB the stronger, sharper, and more honest marker of atherogenic burden:

1. Why ApoB is a better measure of atherogenic burden
2. How ApoB drives atherosclerosis
3. How ApoB fits into clinical practice

We’ll also explore practical takeaways — when to order ApoB, what cutoffs to use, and how to apply it when your LDL and ApoB numbers don’t agree.
By the end, you’ll see why every atherogenic particle counts — and why ApoB just might be the number that finally tells the truth about cardiovascular risk.

Bonus: The Visual Guide for this episode is waiting for you — click here. For the full collection of visuals across episodes, visit the Podcast page.

Download the Free LipidCurious Starter Kit here

Questions or feedback? Reach out at hello@lipidcurious.com

Disclaimer: This podcast is for educational purposes only. It is NOT medical advice.

For decades, HDL — the so-called “good cholesterol” — has been celebrated as the body’s knight in shining armor. Patients brag about their high HDL levels like it’s a shield against heart disease. But is HDL truly the hero we once thought?

In this episode of LipidCurious, we’ll separate myth from science and uncover the real story of HDL:

1. Why is HDL called the “good cholesterol” — and is that nickname really fair?
2. What exactly is reverse cholesterol transport, and why does it matter?
3. Why did drugs that raise HDL fail to improve cardiovascular outcomes?

We’ll also explore clinical twists: how HDL can become dysfunctional in high-triglyceride states, and why extremely high HDL might not always be protective.

Bonus: The Visual Guide for this episode is waiting for you — click here. For the full collection of visuals across episodes, visit the Podcast page.

Download the Free LipidCurious Starter Kit here

Questions or feedback? Reach out at hello@lipidcurious.com

Disclaimer: This podcast is for educational purposes only. It is NOT medical advice.

Picture an atherosclerotic artery as a crime scene. Cholesterol piles up on the walls — thick deposits blocking what should be a free-flowing highway of blood. For decades, cholesterol was blamed as the culprit. But here’s the twist: cholesterol is just the passenger. The real suspects are the lipoproteins — the vehicles smuggling cholesterol into places it doesn’t belong.

In this episode of LipidCurious, we’re stepping into the role of detective. We’ll assemble a lipoprotein from scratch, meet the different lipoproteins, and follow their pathways through the body.

Here’s what we’ll cover together:

1. Structure and types of Lipoproteins

2. Exogenous and endogenous pathways of lipid metabolism

3. How cholesterol-lowering medications leverage lipid biology

Bonus: The Visual Guide for this episode is waiting for you — click here. For the full collection of visuals across episodes, visit the Podcast page.

Download the Free LipidCurious Starter Kit here

Questions or feedback? Reach out at hello@lipidcurious.com

Disclaimer: This podcast is for educational purposes only. It is NOT medical advice.

Cholesterol is one of the most talked-about molecules in medicine — and one of the most misunderstood. It’s essential for life, but when carried in the wrong lipoproteins, it becomes the driving force behind atherosclerosis.

In this episode of LipidCurious, we step away from the headlines and hype to explore what cholesterol really means for clinical practice and board prep.

Here’s what we’ll unpack together:

1. The Cholesterol paradox — why it’s both essential and dangerous.

2. How cholesterol is carried and measured in blood.

3. LDL-C in clinical practice — Targets, Percent Reduction, and How Low is Too Low

Bonus: The Visual Guide for this episode is waiting for you — click here. For the full collection of visuals across episodes, visit the Podcast page.

Download the Free LipidCurious Starter Kit here

Questions or feedback? Reach out at hello@lipidcurious.com

Disclaimer: This podcast is for educational purposes only. It is NOT medical advice.