In this solo podcast episode, Dr. Mike Hart delves into the intricacies of insulin resistance, a prevalent yet misunderstood condition. The episode covers the fundamental role of insulin, what happens during insulin resistance, and its linkage to various diseases like diabetes and heart disease. It includes a detailed discussion on how to measure insulin resistance using markers like triglyceride to HDL ratio, fasting insulin, fasting glucose, and hemoglobin A1c. Dr. Hart also explains the significance of advanced glycation end products (AGEs) and how they contribute to aging and diabetes. Practical tips on improving insulin sensitivity through diet, exercise, and supplements such as fiber, mulberry leaf extract, and berberine are provided. Additional considerations for managing blood sugar levels and preventing insulin resistance are also discussed.

Links:

Fasting Insulin Test: https://medlineplus.gov/lab-tests/insulin-in-blood/

Fructosamine Test: https://medlineplus.gov/lab-tests/insulin-in-blood/

Carnosine: https://examine.com/supplements/carnosine/?show_conditions=true

P5P (Pyridoxal-5-Phosphate): https://examine.com/supplements/vitamin-b6/?show_conditions=true

Show Notes:

00:00 Welcome back to the Hart2Heart Podcast with Dr. Mike Hart

00:56 Understanding Insulin and Insulin Resistance

03:02 Markers and Tests for Insulin Resistance

11:30 Advanced Glycation End Products (AGEs)

14:16 Exercise and Insulin Sensitivity

14:53 "Exercise keeps your body insulin sensitive for up to 48 hours — not just two."

16:21 Nutritional Strategies for Blood Sugar Control

20:59 Supplements and Medications for Blood Sugar Management

—

The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to

cutting through the noise and uncovering the most effective strategies for optimizing health,

longevity, and peak performance. This podcast dives deep into evidence-based approaches to

hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise

protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.

Beyond health science, we tackle the intersection of public health and politics, exposing how

policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.

Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary

(Commissioner of the Food and Drug Administration (FDA) and high-profile names such as

Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).

If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.

Connect on social with Dr. Mike Hart:

• Instagram: https://www.instagram.com/drmikehart/

• Twitter: https://twitter.com/drmikehart

• Facebook: https://www.facebook.com/MikeHartEPS/

In this episode, host Dr. Mike Hart welcomes neuroscientist and author Dr. Ben Rein to discuss his new book, 'Why Brains Need Friends: The Neuroscience of Social Connection.' Dr. Rein shares his journey in neuroscience, his research on autism and MDMA, and his pivot towards science communication. They delve into the devastating effects of loneliness, comparing its impact on mortality to smoking 15 cigarettes a day, and explore why human connections are critical for our brain health. Dr. Rein also discusses the benefits of having pets, the intricate balance of social interactions across a lifespan, the effects of MDMA on feelings of connection, and the role of oxytocin in social bonding. This episode provides a deep dive into the science behind social interactions, offering actionable insights to improve mental health and wellbeing.

Dr. Ben Rein is a neuroscientist, educator, and science communicator whose work explores the biology of human connection, empathy, and social behavior. With a Ph.D. in neuroscience and postdoctoral research at Stanford University, Dr. Rein has studied everything from the neural underpinnings of autism spectrum disorder to how MDMA (ecstasy) enhances empathy in the brain.

Follow his work at mindscience.org or connect with him on Instagram.

Links:

• Oxytocin ("the love hormone")

• Loneliness and mortality studies

• Stanford University

• Lion's Mane

Show Notes:

00:00 Welcome back to the Hart2Heart podcast with Dr. Mike Hart

00:30 Dr. Ben Rein's background and new book

02:30 The loneliness epidemic and its effects

04:00 The science behind social interaction

04:15 " Being isolated is worse for you or as bad for you as smoking 15 cigarettes a day."

10:30 Extroversion vs. introversion: social needs

24:00 Oxytocin: the love hormone

33:00 Teamwork and social bonds

36:30 The power of tribalism in sports

38:00 Romantic relationships and health

42:00 The impact of loneliness across a lifetime

49:00 Social media and loneliness

01:02:00 The therapeutic potential of MDMA

—

The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to

cutting through the noise and uncovering the most effective strategies for optimizing health,

longevity, and peak performance. This podcast dives deep into evidence-based approaches to

hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise

protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.

Beyond health science, we tackle the intersection of public health and politics, exposing how

Policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.

Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary

(Commissioner of the Food and Drug Administration (FDA) and high-profile names such as

Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).

If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.

Connect on social with Dr. Mike Hart:

• Instagram: @drmikehart

• Twitter: @drmikehart

• Facebook: @drmikehart

In this episode of the Heart to Heart podcast, Dr. Mike Hart chats with Dr. Jose Antonio about the evolution and impact of sports nutrition research, particularly focusing on creatine and protein consumption. Dr. Antonio shares his journey from studying muscle physiology to pioneering research in sports nutrition, highlighting the initial skepticism in the scientific community and the eventual acceptance of supplements like creatine. They also delve into the benefits of various supplements for athletic performance, the ongoing debates in the medical field regarding supplementation, and exciting upcoming research on creatine's effects on eye muscle performance in athletes.

Links:

• University of Central Florida – Dr. Jeff Stout

• University of Regina – Dr. Darren Candow (Creatine researcher)

• Protein Intake & High-Protein Diets

• Caffeine + L-Theanine Combination
  
  

Show Notes:

00:00 Welcome back to the Hart2Heart Podcast with Dr. Mike Hart

00:00 Introduction and guest welcome

01:00 Dr. Jose Antonio's academic journey

01:30 Challenges in sports nutrition research

04:00 Breakthrough in sports supplements

08:00 The evolution of sports nutrition

13:00 High protein diet studies

14:20 "We had people eating 600 to 800 extra calories of pure protein—and nothing happened. No fat gain. That alone blew people's minds."

17:00 Protein timing and intake

20:30 Impact of hormones on protein absorption

23:00 Testosterone and protein intake

24:00 Peptides and growth hormone

25:00 Protein timing and casein

25:30 Creatine for brain and muscle

42:00 Mitochondrial health and supplements

—

The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to

cutting through the noise and uncovering the most effective strategies for optimizing health,

longevity, and peak performance. This podcast dives deep into evidence-based approaches to

hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise

protocols, leveraging sunlight light, and de-prescribing pharmaceuticals—using medications only when absolutely necessary.

Beyond health science, we tackle the intersection of public health and politics, exposing how

Policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being.

Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary

(Commissioner of the Food and Drug Administration (FDA) and high-profile names such as

Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen).

If you're ready to take control of your health and performance, this is the podcast for you. We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being.

Connect on social with Dr. Mike Hart:

• Instagram: @drmikehart

• Twitter: @drmikehart

• Facebook: @drmikehart