Are you an executive or business owner secretly wrestling with doubt, fatigue, or fear that your leadership might not be enough in the next storm? What if you could tap into the hard-won secrets of a leader forged in war and tested in biotech’s wildest innovation cycles?

This episode is a high-voltage sit-down between J. Michael Fisher Jr. and David Esposito, CEO of ONL Therapeutics and decorated former Army officer. Together, they crack open the reality of modern leadership, reveal the invisible thread between military service and world-class execution, and share unfiltered routines for resilience and team alignment in chaos.

Listen now if you want to escape the pain of unanchored teams, avoid costly self-doubt, and grab exclusive tools that only proven leaders are teaching. Stakes are high, innovation waits for no one, and these lessons aren’t in any playbook… yet.

[00:01] – Why a Jersey kid chose West Point, and what it revealed about real purpose

[00:22] – The “Aha!” moment: Can military leadership really transfer into biotech?

[00:53] – How ONL Therapeutics protects vision—what most execs miss about relentless innovation

[01:48] – The moment family, community, and business shaped a calling to serve

[03:33] – Crushing self-doubt: Inside the pressure cooker of leading teams when everything’s at stake

[08:32] – What top business athletes, Green Berets, and private equity stars share—The secret ingredient

[13:35] – The 3 proven leadership lessons that build unstoppable companies (and why most miss #3)

[23:48] – Real talk: Managing fatigue, optimism, and the brutal truth when the gut punches keep coming

1. University of Michigan (Dr. David Zaks)
2. West Point
3. 101st Airborne Division (U.S. Army)
4. Bronze Star Medal
5. NIH – National Institutes of Health

David Esposito is the CEO of ONL Therapeutics, a cutting-edge biotech company pioneering life-changing treatments to prevent retinal cell death and preserve vision. A former Army platoon leader awarded the Bronze Star, David is known for his unmatched resilience and ability to transpose battlefield clarity into executive mastery. With more than 30 years in life sciences, he’s led teams through both soaring exits and humbling failures, always championing purpose and people above the transaction.

🔗 LinkedIn | Website

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What if you could add a decade or more of vibrant, high-performance living to your life, starting now?

In this electrifying episode, J. Michael Fisher Jr. sits down with Jean Fallacara, scientist, serial entrepreneur, and founder of Lifespan, to decode the real science (and the misunderstood buzz) behind biohacking for busy leaders. From building $100M companies on only four hours of work daily to practical strategies for outsmarting burnout and building true resilience, Speaker B reveals what actually moves the needle for high achievers.

You’ll get straight talk (and specific tips) on how to reclaim your health span, optimize work blocks for explosive focus, and create routines even skeptics can stick with. Don’t miss the battle-tested blueprint that could literally change—maybe even save—your life.

Listen now: the cost of inaction is years of lost vitality, thriving, and leadership edge. The only place you’ll hear these transformative, exclusive tactics is in this episode.

[00:01:00] – What “biohacking” actually means (and why we shouldn’t need a word for it)

[00:06:18] – From selling postcards on the street to $32M exits: Speaker B's origin story

[00:11:29] – The biggest entrepreneurship myth: why sleep deprivation signals failure, not hustle

[00:12:40] – How Speaker B ran a 205-person company in just four hours a day

[00:17:26] – The plan B trap: the brutal indicator you’re not cut out for this

[00:22:42] – The unexpected science (and danger) of ignoring your body’s natural cycles

[00:28:57] – “Start with data, but don’t obsess”—the surprising dark side of tracking everything

[00:41:10] – Five tiny daily tweaks that can instantly impact your longevity and performance

• Monroe Institute Hemi-Sync
• Whoop
• Ōura Ring
• Fisher Scientific
• Book: Peter Attia, MD (on healthspan)
• Andon Sound
• Grant Cardone
• Charles Scott (Intel Chief of Staff)
• Andrew Huberman (Huberman Lab, circadian rhythm science)

Jean Fallacara is the founder and CEO of Lifespan, a breakthrough longevity platform making radical health optimization accessible to everyone. A renowned scientist, technologist, and serial entrepreneur, Jean has launched and exited 11 companies, managing teams of 200+ and driving $100M+ in annual revenue—all while living out the protocols he teaches. With expertise spanning biotechnology, neurobiology, and AI, Jean leads the charge in democratizing the secrets of peak performance for high achievers worldwide.

🔗 LinkedIn | Website

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Ever felt trapped by your own success, secretly craving a reboot but fearing what’s next?

This isn’t just another ex-exec startup story. Eric Frankel, former Warner Bros. President turned founder of AdGreetz, sits down with J. Michael Fisher Jr. for a raw, revealing conversation on what it truly takes to leap from a billion-dollar seat into entrepreneurship, without a safety net. They dig into the hidden emotional costs, the rush of early wins, and the guts required to walk away from the familiar and reimagine what’s possible (even after 30 years at the top).

If you’ve ever wondered what it’s really like to reinvent your life, build a next-level team, and find meaning beyond the deal, press play now. The pain of staying stuck is real, and the window to thrive is closing. This episode offers unfiltered, exclusive takeaways for leaders who don’t just want to win, they want to matter.

[00:01:27] – How a single call from the chairman turned a lifelong New Yorker into a Los Angeles media boss

[00:04:04] – The boyhood obsession with film that shaped a future executive—and the “aha” moment of radical delegation

[00:09:26] – When the right story lands, doors fling open: The secret portfolio that made competitive hiring a breeze

[00:12:53] – Navigating money, family, and meaning: Why he walked away from millions (twice) to start over

[00:19:54] – The simple trigger behind AdGreetz: Realizing brands never talk “to” you, just “at” you

[00:29:32] – Are you a “cat in the data mine”? How AdGreetz wins at personalization without crossing the line

[00:36:34] – Why B2B targeting is harder and what most sales teams still get wrong in 2024

[00:44:00] – Frankel’s daily success routine: trainers, sleep, boundaries… and admitting when to take the L

• BizGreetz
• Warner Bros.
• Syracuse University Concert Committee
• Fred Silverman (TV programming legend)
• Nike
• Kiehl’s
• Barney’s New York
• Columbia House
• Stone Pony (music venue)
• Cole Haan
• Salesforce and Adobe (as B2B marketing examples)
• Landmark Theatre (Syracuse)

Eric Frankel is the Founder and CEO of AdGreetz, a cutting-edge personalization platform transforming how brands communicate with customers. Previously, he spent 30 years climbing the ranks at Warner Bros., where he ultimately served as President of Warner Bros. Domestic Cable Distribution. A sought-after innovator in media and tech, Frankel blends deep entertainment industry insight with a bold, data-driven approach to modern marketing.

🔗 LinkedIn |