Greg and Matias interview Natalie Yivgi-Ohana of Minovia. Natalie is a life science entrepreneur with twenty years’ experience in mitochondrial research and received her PhD in Biochemistry at The Hebrew University in 2007, after which she performed her postdoctoral fellowship at the Weizmann Institute of Science until 2010.

In this episode, we discuss:

• How mitochondria impacts health by not just regulating energy, but also hormones, cell survival, and overall cellular function
• Why mitochondrial dysfunction is a root cause of many conditions, from rare genetic disorders to aging and mental health issues.
• What mitochondrial therapy does by restoring function and improving cellular health
• What makes mitochondrial therapies distinct from gene therapies
• How to scale mitochondrial therapies for clinical adoption

Credits:

Created by Greg Kubin and Matias Serebrinsky
Host: Matias Serebrinsky & Greg Kubin
Produced by Caitlin Ner & Nico V. Rey

Find us at businesstrip.fm and psymed.ventures
Follow us on Instagram and Twitter!
Theme music by Dorian Love
Additional Music: Distant Daze by Zack Frank

Matias and Greg interview Ying-Hui Fu, PhD, is a Professor of Neurology at UCSF and a world leader in the genetics of sleep. Her lab has discovered the first-known genes behind “natural short sleepers”. Her work bridges human genetics and neuroscience to uncover how to modulate sleep for brain health, aging, and neurodegenerative diseases.

In this episode, we discuss:

• How some people thrive on 4–6 hours of sleep with rare genetic mutations
• Why sleep efficiency is more important than total hours slept
• What short sleeper genes reveal about preventing Alzheimer’s and autism
• Why current sleep research tools miss deeper brain activity patterns
• What’s next in sleep science with potential therapies

Credits:

Created by Greg Kubin and Matias Serebrinsky
Host: Matias Serebrinsky & Greg Kubin
Produced by Caitlin Ner & Nico V. Rey

Find us at businesstrip.fm and psymed.ventures
Follow us on Instagram and Twitter!
Theme music by Dorian Love
Additional Music: Distant Daze by Zack Frank

Matias and Greg interview Justin Mares, co-founder of TrueMed and Kettle & Fire on current US healthcare and how startups have the opportunity to change the system.

In this episode, we discuss:

• How the US system profits from chronic illness
• Fixing the food system, environmental toxins, pharma incentives & more
• Opportunities for founders building in brain and body health.
• Contrarian ideas Justin is investing in today

Credits:

Created by Greg Kubin and Matias Serebrinsky
Host: Matias Serebrinsky & Greg Kubin
Produced by Caitlin Ner & Nico V. Rey

Find us at businesstrip.fm and psymed.ventures
Follow us on Instagram and Twitter!
Theme music by Dorian Love
Additional Music: Distant Daze by Zack Frank