Jolly Copper is one of the few people who know the world is on the brink of cataclysmic destruction.... not because he had any scientific knowledge or prophetic dreams, but because he is nosey and read what was on a fellow bus passenger's phone one day. He learns there will be an unprecedented series of natural disasters, and the expected grand finale disaster is predicted to be a tidal wave massive enough to swallow half the globe.

Following a control breach at a top-secret facility, a weapons grade biological pathogen, YPP-234, escapes and quickly spirals out of control. It is deadly, it is fast, and it goes unnoticed until it is too late. YPP-234 isn’t just a manmade biological weapon, it is a manmade extinction level event. Now it is out.

In the height of the Cold War, in the aftermath of Hiroshima, in the fear of nuclear annihilation, in the heart of West Virginia the surviving salvation was born. A huge bunker designed to house 1,000 people, most of which were government officials, was constructed and code named "Project Greek Island" for secrecy. In 1995, the secret was exposed and the United States Government ultimately revealed this buried treasure. It was nestled in the hills of West Virginia 750 feet beneath a plush resort. A few years later, the resort made the bunker a tourist attraction and offered tours for the curious.

Greg Benedict watches in horror as his wife and baby stand by the window inside of a burning building. Then, before the flames reach them, they vanish. It was just the beginning. Sporadic vanishings occur over the next several months, all leading to the day when half the population disappears. Gone. Chaos ensues as humanity struggles to come to grips with the sudden vanishing of half the life on Earth.

On a late spring day, the United States of America is hit with a biological terror attack that brings the nation to her knees. The virus is deadly and highly contagious. It spreads like wildfire, infecting, and killing almost everyone it hits.

When the news of an impending extinction-level meteor impact is made public, humanity struggles to find some way to survive. Violet journals her life in a notebook in the form of letters to her grandmother. They start out sarcastic and funny, as she shares entertaining and exaggerated tales of her teenage life. But when Violet finds out about the meteor, everything changes. Suddenly she is thrust into a grown-up world, and her survival isn't guaranteed.

It is a very rare occasion that Abby Miller travels into the city, but an errand that can only be done in town prompts her to make it a girls' day out with her two daughters. Unfortunately, the day is far from perfect and they are in the worst place possible when nuclear war strikes... ground zero.

What starts as an emergence of a new virus quickly turns into Mother Nature’s ultimate population control. While attending a seminar at the Ambassador Hotel, Ava Mason is unknowingly exposed to a carrier of a highly contagious virus. The next morning, she wakes to a steady pounding on her door. Within minutes, her home is stormed and she and her three children are apprehended, placed in a van and taken away. They are told nothing. No one is. Ava, her children, and others are brought to the Ambassador and sealed in.

Before the sun rose over the town of Sisterville, everything went black. A natural disaster of unknown origins takes the lives of every living creature and decimates the small town. Disgraced NASA scientist and now Cleveland weatherman Hero Galanis knows he is more than a local celebrity on television. He recognizes the anomaly on the satellite image as a repeat of the event that cost him his career. Decades earlier, Hero made predictions about the devastation the anomaly would cause, but those predictions pale in comparison to the reality the world currently faces.

When an outbreak of H7N2, or as the news calls it, Whitby Fever, begins striking cats and dogs, it is newsworthy but not panic-inducing, until it is confirmed that Whitby Fever has crossed the boundaries, spreading from domestic pets to humans at an astronomical rate. Mills Run, Ohio, is not much different from any other small town. The residents have a bond and kinship. The townspeople brag that Mills Run is isolated, and at times, cut off from the rest of the world. However, not even Mills Run is secluded enough for a global pandemic. 

Darius Cobb wasn't thinking of man's extinction. He honestly never gave it a thought. A college professor and part time country singer, Darius worried only about teaching and playing his guitar until the day he is attacked by cockroaches and is placed into a special government quarantine. There, he and the others start piecing together the inevitable. Using his knowledge, he begins predicting the events that unfold. Together he and his group plan and then implement a long term survival plan.

For a decade now, the world has known of the existence of the immuno-degenerative and epidermal decomposition virus (strain two). The world governments and several civilian agencies have, so far, managed to keep the unimaginable from happening. They achieved it by keeping the outbreaks under control and preventing a global pandemic.

A mysterious growth covers three deer on Miller Run Road outside of Griffin, Arizona. The sickly animals are mistaken for scared until they brazenly attack a car, causing a fatal accident. Like everyone else in town, Cass “Scoop” McDaniels has lived in Griffin her entire life. When she is assigned the accident story, her findings are dismissed. The story dies with the people on the road. But Cass doesn’t give up.

Without warning the United States is invaded and attacked. The result: World War III. In the sanctity of her shelter, Joanna Collins reconciles her life on the pages of a notebook. In doing so, she gains the determination to discover what has become of those she loves in a world that has turned to dust.

Danny Bishop is successful, happy, and the epitome of a good person. Young and energetic, there is no obstacle Danny believes he won't overcome. Life is his highway, one he designed. Everything is ideal until that road comes to a grinding halt and Danny finds out he has six weeks to live.