Shocking cases of abusive medical research and the whistleblowers who spoke out against them, sometimes at the expense of their careers. The Occasional Human Sacrifice is an intellectual inquiry into the moral struggle that whistleblowers face and why it is not the kind of struggle that most people imagine.

We are on the cusp of a major transformation in healthcare—yet few people know it. At top hospitals and a few innovative health-tech startups, scientists are working closely with patients to dramatically extend their "healthspan"—the number of healthy years before disease sets in. In The Age of Scientific Wellness, two visionary leaders of this revolution in health take us on a thrilling journey to this new frontier of medicine.

Just months ago, millions of people were stunned by ChatGPT's amazing abilities–and its bizarre hallucinations. But that was 2022. GPT-4 is now here, with smarter, more accurate, and deeper technical knowledge. GPT-4 and its competitors and followers are on the verge of transforming medicine. But with lives on the line, you need to understand these technologies–stat.

David Fajgenbaum, a former Georgetown quarterback, was nicknamed the Beast in medical school, where he was also known for his unmatched mental stamina. But things changed dramatically when he began suffering from inexplicable fatigue. In a matter of weeks, his organs were failing and he was read his last rites. Doctors were baffled by his condition, which they had yet to even diagnose. Floating in and out of consciousness, Fajgenbaum prayed for a second chance, the equivalent of a dramatic play to second the game into overtime.

The effort to destroy facts and make America ungovernable didn't come out of nowhere. It is the culmination of seventy years of strategic denialism. In On Disinformation, Lee McIntyre shows how the war on facts began, and how ordinary citizens can fight back against the scourge of disinformation that is now threatening the very fabric of our society.

An entertaining deep dive into muscle, from the discovery of human anatomy to the latest science of strength training.

Optimization is the driving principle of our modern world. We now can manufacture, transport, and organize things more cheaply and faster than ever. Optimized models underlie everything from airline schedules to dating site matches. We strive for efficiency in our daily lives, obsessed with productivity and optimal performance. How did a mathematical concept take on such outsize cultural shape? And what is lost when efficiency is gained? Optimal Illusions traces the fascinating history of optimization from its roots in America’s founding principles to its modern manifestations.

According to estimates, the healthcare AI market will grow to over $45 billion by 2026. Now is the time for everyone involved, including medical consumers and entrepreneurs, to understand and embrace the AI in healthcare revolution. AI continues to advance at breakneck speeds. Nowhere else is AI moving faster than in the health care sector, where it’s being used to improve millions of lives at every point in the healthcare system. In this book, you will take a deep dive into the remarkable strides that AI is making.

Since Copernicus, humanity has increasingly seen itself as adrift, an insignificant speck within a large, cold universe. Brazilian physicist, astronomer, and winner of the 2019 Templeton Prize Marcelo Gleiser argues that we’re using the wrong paradigm to relate to the universe and our position in it. In this deeply researched and beautifully rendered book, he calls for us to embrace a new life-centric perspective, one which recognizes just how rare and precious life is and why it should be our mission to preserve and nurture it.

When economist Angus Deaton immigrated to the United States from Britain in the early 1980s, he was awed by America’s strengths and shocked by the extraordinary gaps he witnessed between people. Economics in America explains in clear terms how the field of economics addresses the most pressing issues of our times—from poverty, retirement, and the minimum wage to the ravages of the nation’s uniquely disastrous health care system—and narrates Deaton’s own account of his experiences as a naturalized US citizen and academic economist.

In GATTACA Has Fallen: how population genetics failed the populace, Dr. Ian Myles explains that the root of all of these issues is the belief that genetics meaningfully guide our fate. Using less controversial examples like eczema and allergic diseases, the book demonstrates how claiming there are genes for asthma is similar to claiming there are genes for intellect or favorite flavor of tea.

Scientists are learning more and more about how brain activity controls behavior and how neural circuits weigh alternatives and initiate actions. As we probe ever deeper into the mechanics of decision making, many conclude that agency—or free will—is an illusion. In Free Agents, leading neuroscientist Kevin Mitchell presents a wealth of evidence to the contrary, arguing that we are not mere machines responding to physical forces but agents acting with purpose.

In The Genome Odyssey, Dr. Euan Ashley, Stanford professor of medicine and genetics, brings the breakthroughs of precision medicine to vivid life through the real diagnostic journeys of his patients and the tireless efforts of his fellow doctors and scientists as they hunt to prevent, predict, and beat disease.

For more than a century, Dr. J. Marion Sims was hailed as the “father of modern gynecology.” He founded a hospital in New York City and had a profitable career treating gentry and royalty in Europe, becoming one of the world’s first celebrity surgeons. Statues were built in his honor, but he wasn’t the hero he had made himself appear to be. Sims’s greatest medical claim was the result of several years of experimental surgeries—without anesthesia—on a young enslaved woman known as Anarcha; his so-called cure for obstetric fistula forever altered the path of women’s health.

Cystic fibrosis was once a mysterious disease that killed infants and children. Now it could be the key to healing millions with genetic diseases of every type - from Alzheimer's and Parkinson's to diabetes and sickle cell anemia. Told from the perspectives of the patients, families, physicians, scientists, and philanthropists fighting on the front lines, Breath from Salt is a remarkable story of unlikely scientific and medical firsts, of setbacks and successes, and of people who refused to give up hope....