When the Dionne Quintuplets were born on May 28, 1934, weighing a grand total of just over 13 pounds, no one expected them to live so much as an hour. Overnight, Yvonne, Annette, Cécile, Émilie, and Marie Dionne mesmerized the globe, defying medical history with every breath they took. In an effort to protect them from hucksters and showmen, the Ontario government took custody of the five identical babies, sequestering them in a private, custom-built hospital across the road from their family - and, in a stunning act of hypocrisy, proceeded to exploit them for the next nine years.

In 1918, Philadelphia was a city teeming with promise. Even as its young men went off to fight in the Great War, there were opportunities for a fresh start on its cobblestone streets. Into this bustling town came Pauline Bright and her husband, filled with hope that they could now give their three daughters - Evelyn, Maggie, and Willa - a chance at a better life. But just months after they arrive, the Spanish flu reaches the shores of America.

In the last months of the Nazi occupation of Poland, two children are left by their father and stepmother to find safety in a dense forest. Because their real names will reveal their Jewishness, they are renamed "Hansel" and "Gretel". They wander in the woods until they are taken in by Magda, an eccentric and stubborn old woman called "witch" by the nearby villagers.

London, 1915. As German bombs rain down on the East End of London and hungry children queue for rations in the blistering cold, 15-year-old Florrie is forced to grow up fast. With her father fighting in the muddy trenches, Florrie turns to her older sister Edith for comfort. But the war has changed Edith. She has grown quiet, with dark shadows under her eyes, and has started leaving the house at night in secret. When Florrie follows her sister through the dark and winding streets of London, she is shocked by what she discovers.

Del Wensley, wife of the most celebrated preacher in Harlan County, tries to mind her place. Until her husband’s infidelity pushes an already strained marriage to a breaking point. Clinging to her last hope for self-respect, Del turns her back on the rigid life she’s known. A coal train is rolling through the valley. With her eyes wide open to the unfamiliar, and to the freedom she craves, Del takes to the rails.

Evie and Thomas experience a very different war. Frustrated by life as a privileged young lady, Evie longs to play a greater part in the conflict - but how? - and as Thomas struggles with the unimaginable realities of war, he also faces personal battles back home, where War Office regulations on press reporting cause trouble at his father's newspaper business. Through their letters Evie and Thomas share their greatest hopes and fears - and grow ever fonder from afar. Can love flourish amid the horror of the First World War, or will fate intervene?

New York City, 1926. Nurse Althea Anderson's heart is near breaking when she witnesses another premature baby die at Bellevue Hospital. So when she reads an article detailing the amazing survival rates of babies treated in incubators in an exhibit at Luna Park, Coney Island, it feels like the miracle she has been searching for. But the doctors at Bellevue dismiss Althea and this unconventional medicine, forcing her to make a choice between a baby's life and the doctors' wishes that will change everything. 

Practical Melanie Middleton hates to admit she can see ghosts. But she's going to have to accept it. An old man she recently met has died, leaving her his historic Tradd Street home, complete with housekeeper, dog - and a family of ghosts anxious to tell her their secrets. Enter Jack Trenholm, a gorgeous writer obsessed with unsolved mysteries. He has reason to believe that diamonds from the Confederate Treasury are hidden in the house. So he turns the charm on with Melanie, only to discover he's the smitten one....

When a chance encounter with Theodore Camden, one of the architects of the grand New York apartment house the Dakota, leads to a job offer for Sara Smythe, her world is suddenly awash in possibility - no mean feat for a servant in 1884. The opportunity to move to America. The opportunity to be the female manager of the Dakota. And the opportunity to see more of Theo, who understands Sara like no one else...and is living in the Dakota with his wife and three young children.

Sophie Whalen is a young Irish immigrant so desperate to get out of a New York tenement that she answers a mail-order bride ad and agrees to marry a man she knows nothing about. San Francisco widower Martin Hocking proves to be as aloof as he is mesmerizingly handsome. Sophie quickly develops deep affection for Kat, Martin's silent five-year-old daughter, but Martin's odd behavior leaves her with the uneasy feeling that something about her newfound situation isn't right.

February, 1946. World War Two is over, but the recovery from the most intimate of its horrors has only just begun for Annaliese Lange, a German ballerina desperate to escape her past, and Simone Deveraux, the wronged daughter of a French Résistance spy. Now the two women are joining hundreds of other European war brides aboard the renowned RMS Queen Mary to cross the Atlantic and be reunited with their American husbands. Their new lives in the United States brightly beckon until their tightly held secrets are laid bare in their shared stateroom.  

Imprisoned in the Lodz Ghetto, Elsi discovers her mother's desperate attempt to end her pregnancy and comes face-to-face with the impossibility of their situation. Risking her own life, Elsi joins a resistance group to sabotage the regime. Blonde, blue-eyed Matilda is wrenched from her family in Romania and taken to Germany, where her captors attempt to mold her into the perfect Aryan child. Spirited and brave, she must inspire hope in the other stolen children to make her dreams of escape a reality.

In 1937, there are recesses in Appalachia no outsiders have ever explored. Two government-sponsored documentarians from Cincinnati, Ohio - a writer and photographer - are dispatched to penetrate this wilderness and record what they find for President Roosevelt’s Works Progress Administration. For photographer Clay Havens, the assignment is his last chance to reboot his flagging career. So when he and his journalist partner are warned away from the remote Spooklight Holler outside of town, they set off eagerly in search of a headline story. 

Elise Sontag is a typical Iowa 14-year-old in 1943 - aware of the war but distanced from its reach. Then her father, a legal US resident for nearly two decades, is suddenly arrested on suspicion of being a Nazi sympathizer. The family is sent to an internment camp in Texas, where behind the armed guards and barbed wire, Elise feels stripped of everything beloved and familiar, including her own identity. The only thing that makes the camp bearable is meeting fellow internee Mariko Inoue, a Japanese-American teen from Los Angeles.

Teeny, Sonny Boy and Vic have been swallowed up by the desperation and devastation of the Great Depression, but the trio is buoyed by the fantastical tales Teeny weaves around campfires in hobo jungles and migrant camps, including the story of the raffle baby. As the three navigate the ravages of poverty and prejudices, they form a family bond as strong as the forces against them. But when a solemn pact fails to protect them, their lives are forever changed. And Sonny Boy is left to tell their story, and his own.